Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Nantong University(Medical Sciences)》 2006-02
Add to Favorite Get Latest Update

Experimental study on anti-tumor effect of Fufang Tiangjian Wan,a Chinese drug on mice with transplanted tumors

LI Feng, ZHANG Wei, WANG Yuqin ,et al (Department of pharmacology, Nantong University, Nantong 226001)  
Objective:To investigate the effect of Fufang Tianjian Wan ,pill of a Chinese drug on tumors,and on the immune system of mice with transplanted tumors.Methods:The tumor-inhibited rate of S180 and Lewis transplanted tumor, and the life-prolonging rate of EAC and HepA tumor-carrying mice were investigated to evaluate the inhibitory effect of Fufang Tianjian Wan on transplanted tumors. The serum half hemolysis value、the function of mononuclear phagocyte、the serum IgG level and the weight of spleen and thymus were detected to evaluate the actions of Fufang Tianjian Wan on mouse humoral immunity system and cellular immunity system. Results:Contrasted with control group, the results of anti-tumor effects revealed the pill(5,2.5g/kg) would inhibit the transplanted tumor growth of S180、Lewis、EAC、HepA remarkably, which showed a dose-dependent effect. Contrasted with control group, the pill could improve the function of mononuclear phagocyte dramatically, which indicated the pill could improve their cellular immunity system; and it could improve mouse serum half hemolysis value depressed by transplanted tumor dramatically, which revealed the pill could improve the mouse humoral immunity system. Conclusion:The mechanism of tumor - inhibition by the pill due to enhance the immune function.
【CateGory Index】: R73-3
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 1 Hits
1 MI Bao-ming et al (Animal Medical College,Gansu Agricultural University,Lanzhou,Gansu 730070);Effects of Chanfukang(Chinese Medicine) on the Cytokine Level of Immunosuppressive Mouse[J];Journal of Anhui Agricultural Sciences;2009-13
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 WANG Mei,QIN Xiao-mei (Department of Respiratory Diseases, The Affiliated Hospital of Qingdao University Medical College, Qingdao 266003, China);;AN EXPERIMENTAL STUDY ON THE ANTITUMOR ACTIVITY OF TRADITIONAL JHL COMPOUND[J];Acta Acadimae Qingdao Umvesitatis;2004-02
2 Wang yong,Hu zhiqian,Chen zhigang,Zhang lingzhen,Wang yuanhe,Department of General Surgery,Chang Zheng Hospital,Second Miliary Medical University.Shanghai 200003;EFFECT OF ASTRAGALUS ON CELLULAR IMMUNE FUNCTION OF RATS WITH OBSTRUCTIVE JAUNDICE[J];JOURNAL OF HEPATOBILIARY SURGERY;2000-01
3 Liang Shaohua Li Minjiang Li TingguanThe Second Affiliated Hospital,Guangxi Medical University of TCM;CLINICAL OBSERVATION ON TREATMENT THE REACTION OF SIDE EFFECTS IN THEPOSTOPERATIVE BREAST CANCER CHEMOTHERAPY WITH SHENG XUE HE ZHONG TANG[J];Guangxi Journal of Traditional Chinese Medicine;2002-04
4 Tian Weiyi,Ma Chun Ling,Bai Hui Qing Department of Immunology, Guiyang College of TCM, Guiyang 550002;Effects of Radix Trichosanthis and its contents on NK Cells' killing activity of mice[J];Guizhon Medical Journal;2001-11
5 ZHOU Yuefen. Lishui District Hospital, Zhejiang Province 323000;Clinical effects of the modified Buyang Huanwu Decoction on postoperative tumefaction of upper limb secondary to the radical mastectomy[J];HEBEI JOURNAL OF TRADITIONAL CHINESE MEDICINE;2000-02
6 LI Hanzhong,HUANG Zhifen,ZHANG Zuojun,et al.Department of Combination of TCM with Western Medicine,Affiliated Tumor Hospital of Guangxi Medical University,Nanning 530021;Clinical observation of electro-acupuncture combined with compound Salvia miltiorrhiza injection in treating lymphatic edema of upper limb of postoperation in the patients with mammary cancer[J];Hebei Journal of Traditional Chinese Medicine;2002-04
7 Zhang Yonghong;Jin Shuwen ( Nanjing University of TCM. Nanjing 210029);Clinical Observation on Antitumor Synergy of Hepatocarcinoma Used with Bugan Ruanjian Decoction[J];SPONSORED BY GUBEI COLLEGE OF TRADITIONAL CHINESE MEDICINE;1998-01
8 ZHANG Xiu-juan 1 ,JI Yu-bin 2 (1.Department of Pharmaceutical Engineering,Harbin University of Commerce,Harbin150076,China;2.Institute of Pharmaceutical Research,Harbin University of Commerce,Harbin150076,China);Studies on Immunological Pharmacology of Fungal Polysaccharides[J];Journal of Heilongjiang Commercial College (Natural Sciences Edition);2002-01
9 REN Delian,ZHONG Desheng,XU Xiaoyu Department of Microbiology and Immunclogy,Luzhou Medical College,Luzhou 64600 China;STUDY ON EFFECTS OF ASTRAGALUS MEMBRANACEUSAND REHMANNIA GLUTINOSA ON THE PROLIFERATION AND THE SPECIFIC ANTITUMOR ACTIVITIES OF TIL FROM ESOPHAGEAL CANCER[J];WEST CHINA JOURNAL OF PHARMACEUTCAL SCIENCES;2000-03
10 YANG Jin giao,ZHAO Jun ling,FAN Wei First University Hospital,West China University of medical Sciences,Chengdu,610041.;Immunodetections of Breast Cancer Patients by Flow Cytometry and Its Clinical Significance[J];WEST CHINA MEDICAL JOURNAL;1999-01
【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
1 YANG Lan 1,YANG Ping di 2,LIANG Rong 1,et al 1 Department of Hematology,Xijin Hospital,The Fourth Military Medical University, Xian 710032, P R China 2 Department of Hematology and Oncology, Naval General Hospital, Beijing 100037, P R;Study on reversal of multidrug resistance in leukemia by tetramethylphylpyrazine combining with cyclosporin A[J];CHINESE JOURNAL OF CANCER;2000-04
2 Liang Jiheng, Zhang Lisheng, Zhang Litu, et al Affiliated Tumor Hospital of Guangxi Medical University, Guangxi Cancer Institute(Nanning 530021);Clinical study on 313 patients of malignant tumor treated with placental immunoregulating factor[J];GUANGXI MEDICAL JOURNAL;1999-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved