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《Acta Academiae Medicinae Nantong》 2009-06
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The clinical study of serum lipids in patients with type 2 diabetes mellitus

YUAN Meiling1,NI Hongbing2(1Department of Otorhinolaryngology,2The Center of Laboratory Medicine,Affiliated Hospital of Nantong University,Nantong 226001)  
Objective:To study the application of lipoprotein,apolipoprotein ApoA1,ApoB100 level and the ratio of ApoA1/ApoB100 in type 2 diabetes mellitus patients associated with cardiovascular disease.Methods:Fifty-five cases of type 2 diabetes mellitus patients were enrolled in this study which were divided into four groups(no complication,one type of complication,two types of complications,three types of complications).Take 47 cases healthy volunteers as control group.All groups of TG,TC,LDL-C,HDL-C,ApoA1,ApoB100 and the ratio of ApoA1/ApoB100 were measured by HITACHI 7600-020 automatic biochemistry analyzer.The results between different groups were compared.Results:Compared with control group,TG,TC,LDL-C,ApoB100 in type 2 diabetes mellitus patients were significantly higher(P0.01),HDL-C and apoA1/ApoB100 significantly lower(P0.05),no significance changes found on ApoA1(P0.05).Compared with type 2 diabetes mellitus patients with no complication,LDL-C and ApoB100 were significantly increased in those associated with complications groups,the ratio of ApoA1/ApoB100 decreased(both P0.05),no significant changes found on TG、TC、HDL-C、ApoA1(P0.05).Conclusion:To check the blood lipids,especially ApoB100 and ApoA1/ApoB100 regularly is very significant for predicting whether there are combined cardiovascular complications in patients with diabetes.
【CateGory Index】: R587.1
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