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《Ningxia Medical Journal》 2012-06
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Clinical study of knee osteoarthritis by manipulation combined with ozone injection

ZHOU Yu,et al.Ningxia People's Hospital,Yinchuan 750021,China  
Objective To study efficacy of knee osteoarthritis treatment by single manipulation therapy and manipulation therapy with ozone injection in joint cavity.Methods Selected 60 cases of knee osteoarthritis patients randomized divided into manipulation therapy group(A group) and manipulation therapy group with ozone injection in joint cavity group(B group).Group A applied Donovani manipulation method,each time 20min,weekly 2 times.Group B applied manipulation therapy with ozone injection in articular cavity 40μg/ml once a week,20ml/each time,course of treatment 20 weeks.Evaluation of through VAS score,HSS score and Noyes loss of joint cartilage score.Results There was a self compared significant differences in pre and post therapy of each group by VAS score,HSS score,Noyes loss of joint cartilage score(P0.05).VAS score in group A was 3.18±0.76 and was 2.62±0.55 in group B.There was a significant differences between two groups(P0.05).There was no significant differences in HSS score between two groups(P0.05).Group A of post treatment of Noyes loss of joint cartilage score was 3.32±0.98,and group B was 2.79±1.2.There was a significant differences(P0.05).Conclusion There is an effective result in single manipulation therapy and manipulation therapy with ozone injection in joint cavity.There is a treatment effectiveness of manipulation therapy with ozone injection in joint cavity than single manipulation therapy in pain control and promotion of compound joint cartilage repair and worth for further study.
【Fund】: 宁夏自然科学基金资助项目(NZ09158)
【CateGory Index】: R684
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