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《Pesticides》 2005-10
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Preliminary Studies on the Mechanism of Metsulfuron Inhibition in Anabaena flos-aquae

ZHANG Xin-Ping, HU Xian-Wen, YUE Xia-Li, DONG Yuan-Yan(College of Sciences, Huazhong Agricultural University, Wuhan 430070, China)  
Susceptibility of acetolactate synthase (ALS) was compared in vitro and in vivo in Anabaena flos-aquae todetermine the mechanism of ALS inhibition by metsulfuron. In vitro ALS from A. flos-aquae was strongly inhibited bymetsulfuron, with higher concentrations producing greater inhibition and an IC50 of 0.026 mg/L. Metsulfuron at 0.001mg/L showed almost no ALS inhibition in vivo, possibly due to metsulfuron breakdown by A. flos-aquae. At metsulfuronconcentrations from 0.01 to 10 mg/L, A. flos-aquae ALS inhibition was basically equivalent to inhibition in vitro, withan IC50 of 0.714 mg/L.
【Fund】: 国家自然科学基金重点项目资助课题(No.49831005)
【CateGory Index】: S482.4;
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