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《JOURNAL OF DERMATOLOGY AND VENEREOLOGY》 1998-01
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Serum levels of cytokines in Vitiligo

Xu Bing et al(Departmet of Dermatology, First Affiliated Hospital, Zhejiang Medical University)  
The concentrations of interleukin 2(IL-2), soluble interleukin-2 receptor(sIL-2R) and tumor necrosis factor (TNFα)were measured in the sera of patients with non-segmental vitiligo (n=41)and in healthy controls (n=30) by and ELISA technique in order to investigate the changes in cellular immunity in vitiligo. The results showed that serum IL-2 levels were significantly decreased and serum levels of sIL-2R and TNFα were significantly elevated in vitiligo group compare with normal controls. These results indicate that deficiencies in cellular immunity may be present in non-segmental vitiligo patients, and suggest that immune mechanisms may be involved in the pathogenesis of vitiligo.
【Key Words】: Vitiligo interleukin tumor necrosis factor
【CateGory Index】: R758.41
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Chinese Journal Full-text Database 1 Hits
1 ;Research Progress in Treatment of Vitiligo[J];Hunan Guiding Journal of Traditional Chinese Medicine and Pharmacology;2004-12
【Citations】
Chinese Journal Full-text Database 1 Hits
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【Co-citations】
Chinese Journal Full-text Database 1 Hits
1 Tu Caixia, Fu Hongwen, Lin Xiran. Department of Dermatology, The First Affiliated Hospital of Dalian Medical University, Dalian 116011;Levels of Soluble Interleukin-2 Receptor in the Sera and Skin Tissue Fluids of Patients with Vitiligo[J];Chinese Journal of Dermatology;1997-04
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Chinese Journal Full-text Database 10 Hits
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