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《Chinese Journal of Clinical Rational Drug Use》 2016-13
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Clinical and coronary lesion characteristics in 1300 patients underwent PCI with family history of coronary heart disease

ZHOU Yan-min;SUN Zhong-hua;ZHONG Ming-hui;TEDA International Cardiovascular Hospital;  
Objective To explore the clinical and coronary lesion characteristics in patients with percutaneous coronary intervention( PCI) with family history( FH) of coronary heart disease( CHD). Methods A total of 13 800 patients,who underwent PCI,from December 2006 to June 2014 were enrolled in the study,screening patients with FH of CHD 1300 casea( positive group). Selected 1000 patients underwent PCI without FH of CHD as negative group. Compared the coronary artery disease and clinical characteristics of family history of CHD positive and negative groups. Results 1300 cases of positive family history of CHD were found among 13 800 cases of PCI patients,accounting for 9. 4% of the total PCI. Patients in positive group and negative group had no difference in BMI and the incidence of diabetes,hypertension,left main lesions and single /double / three vessel lesions( P 0. 05). The onset age and proportion of smokers of positive group were significantly lower than negative group( P 0. 05). In positive group,the proportion of men and the incidence of hyperlipidemia,acute myocardial infarction( AMI),ostial lesion,chronic total occlusion( CTO) were significantly greater than negative group,the difference were statistically significant( P 0. 05). Conclusion The positive rate of FH of CHD in patients underwent PCI are 9. 4%. The proportion of men and the incidence of hyperlipidemia,AMI and complicated coronary artery lesions in patients with FH of CHD ere greater than those no FH of CHD.
【CateGory Index】: R541.4
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