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《Practical Journal of Medicine & Pharmacy》 2011-02
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Clinical evaluation on the diagnosis value of LN level in serum for hepatic fibrosis

WANG Jun,ZHAO Quan,LU Ying,et al.Dept.of Medical Examination,the 401st Hospital of PLA,Qingdao,Shandong 266071,China  
Objective To research for the diagnostic value of LN for hepatic fibrosis.Methods Chemi-luminescence immunoassay(CLIA) was used to measure the level of LN in serum of 92 patients with virus hepatitis and 70 healthy people.The data combined with the pathological alteration were analyzed.Results The level of LN in serum of patients with medium chronic hepatitis obviously heightened,and the LN level of hepatocirrhosis were the highest.Differences anong these 4 groups and with the control groups were significant(P0.05).The increased degree was positively related to the degree of hepatic fibrosis and severity of liver disease,but the correlation with the degree of liver's inflammation and necrosis was not obvious.Conclusion Detecting the level of LN in serum dynamicly can reflect the fibrosis degree of chronic liver disease and the prognosis of patients.
【CateGory Index】: R575.2
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