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《Journal of Qilu Oncology》 2003-03
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Study on Aloe Extract C Induced TNF in Mice

HE Shen,MENG Sheng nan,XIE Guang lin,et al.College of Basic Medical Science,China Medical University,Shenyang 110001,China  
Objective To study the effect on Aloe Extract C (AE C) inducing TNF in mice.Methods Mice were injected with AE C into abdominal cavity for 5 days,obtaining blood and separating serums in the sixth day.Y 99 ,L 929 and A 549 tumor cell lines were used as target cells to assay TNF activity in the serums,the activity in sensitizing for temperature and concentration of the serums.Results AE C induced TNF in BALB/C mice,and as compared with control it had a significant difference ( P 0 01).TNF activity reached a peak in 24 hours after injecting AE C and began to drop in the fouth day.The sample of serums had not activity after 5 days in room temperature and had still activity when it be diluted by 200 times.Conclusion AE C has the effect by inducing TNF in BALB/C mice. China J Cancer Prev Treat,2003,10(3):247-249
【Fund】: 辽宁省科委课题 ( 982 2 5 0 0 3 )
【CateGory Index】: R73-36
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