Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Qilu Oncology》 2003-03
Add to Favorite Get Latest Update

Value of CEA,NSE and CYFRA21-1 in Patients with Advanced Lung Carcinoma

SONG Li hua,SONG Xian rang,ZHANG Xi qin,et al.Shandong Tumor Hospital & Institute,Jinan 250117,China  
Objective To evaluate the value of CEA,NSE and CYFRA21 1 in patients with advanced lung carcinoma.Methods These tumor markers in serum were measured in 79 patients with advanced lung carcinoma using biotin strepavidin EIA.Results The level of CEA,NSE and CYFRA21 1 in patients with advanced lung carcinoma before treatment was significantly higher than that in controls.Single analysis showed that CEA for adenocarcinoma,NSE for small cell lung cancer and CYFRA21 1 for squamous carcinoma had higher positive rate.Combination of these tumor markers increased sensitivity.After chemotherapy (curative effects:CR PR),the serum levels of the markers in patients with object remission was decreased significantly.Conclusions Measurement of CEA,NSE and CYFRA21 1 in serum provides useful information for diagnosis and evaluation of disease extent in patients with advanced lung cancer.The ratio of NSE to CYFRA21 1 is a wonderful index correlated to the pathologic type.The changement of biomarkers serum level reflects the effects of chemotherapy. China J Cancer Prev Treat,2003,10(3):272-275
【CateGory Index】: R734.2
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 8 Hits
1 Wang Hongyu Qu Fenglian # Zhang Xiangru Zhou Yunfei et al Cancer Institute & Hospital,CAMS & PUMC,Beijing 100021,China;A study of correlation between serum CEA,NSE,Cyfra21-1 levels and stage,response and survival in patients with lung cancer[J];Oncology Progress;2004-04
2 CHEN Wu,SUN Yan-li,XI Yan(Dept.of Nuclear Medicine,Jilin Provincial Cancer Hospital,Changchun 130012,China);Correlation Between Serum Tumor Marker Level and Stage,Therapeutic Response and Survival in Patients with Lung Cancer[J];Labeled Immunoassays and Clinical Medicine;2008-04
3 Guo Nan-nan1,2,Tang Jian2,Li Jie2,Yu Jian-qi2,Wei Cheng-ze1,Yu Chang-hai2(1.Academy of military medical sciences Beijing 100850,China,2.Department of Thoracic-cardio Surgery,the First Affiliated Hospital of PLA General Hospital,Beijing 100048,China);The clinical correlation between prognosis of NSCLC and its serum tumor marker changes of pre-operation and post-operation[J];Clinical Journal of Medical Officers;2011-02
4 WEI Bin,CAO Cheng-qi,WEI Ya-ping Department of Oncology,Fuxing Hospital,Capital University of Medical Sciences,Beijing 100038,China;Correlation between serum CEA level and stage,response,survival in patients with lung cancer[J];Journal of Modern Oncology;2009-11
5 MAO An-hua,LI Lian-kun(Department of Clinical Laboratory, Hunan Provincial Maternal and Child Heath Hospital,Changsha 410008,Hunan);Evaluation of Clinical Validity of Combination Measurement of Tumor Markers in Diagnosis of Lung Cancer[J];Practical Preventive Medicine;2006-02
6 XIAO Ling(The People's Hospital of Xiangxi Autonomous Prefecture,Jishou 416000,Hunan);Clinical Significance of Combination Measurement of Tumor Markers in Diagnosis of Lung Cancer[J];Practical Preventive Medicine;2009-04
7 YANG Hong-mei1,LI Fang2,WANG Xiang-chen1,LU Li-you1(1.Department of Medical Laboratory,Yantai China-France Friendship Hospital,Yantai 264001,China;2.Department of Immunology,Dalian Meical University,Dalian 116044,China);Detection and clinical significance of serum CEA,CYFRA21-1 and NSE in patients with lung cancer[J];Chinese Journal of Microecology;2010-07
8 Ma Shuping Qin Jianwen Zhou Jingmin et alDepartment of Thoracic Medicine,Tianjin Chest Hospital, Tianjin;Clinical Evaluation of Tumor Markers in Chemotherapy on Lung Cancer[J];Chinese Journal of Clinical Oncology;2005-10
【Co-citations】
Chinese Journal Full-text Database 1 Hits
1 Feng XUE1,Liyan WANG1,Mingyan ZHANG2,Li CAI2 1Department of Medical Oncology,Heilongjiang Provincial Hospital,Harbin 150001,China;2Department of Medical Oncology,the Third Affiliated Hospital of Harbin Medical University,Harbin 150040,China;Clinical Significance of Detection of Serum Values of Neuron Specific Enolase Before and After Treatment for Small Cell Lung Cancer[J];Chinese Journal of Lung Cancer;2011-09
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 PAN Qiang-rong1*,ZHANG Xing1,XU Ze-feng1,ZHENG Shu21.Clinical Experimental Research C enter,The Second Affiliated Hospit al,School of Medicine,Zhejiang University,Hangzhou 310009,P.R.China2.Cancer Research Institute,Zheji ang University,Hangzhou 310009,P.;Significance of Combined Determination of CK19mRNA,Carcinoembryanic Antigen,Neuron-Specific Enolase,and Tissue Polypeptide Antigen in Peripheral Blood of Patients with Lung Cancer[J];Chinese Journal of Cancer;2002-02
2 Pan Huizhong  Huang Peiqi  Su BoShanghai First Pneumology Hospital, Shanghai, 200433  ;The significance of CYFRA211 in diagnosis,commenting therapeutic value and prognosis for pulmonary carcinoma[J];CHINESE JOURNAL OF CANCER;1998-01
3 Wang Hongyu Qu Fenglian # Zhang Xiangru Zhou Yunfei et al Cancer Institute & Hospital,CAMS & PUMC,Beijing 100021,China;A study of correlation between serum CEA,NSE,Cyfra21-1 levels and stage,response and survival in patients with lung cancer[J];Oncology Progress;2004-04
4 CHEN Wu,SUN Yan-li,XI Yan(Dept.of Nuclear Medicine,Jilin Provincial Cancer Hospital,Changchun 130012,China);Correlation Between Serum Tumor Marker Level and Stage,Therapeutic Response and Survival in Patients with Lung Cancer[J];Labeled Immunoassays and Clinical Medicine;2008-04
5 ;Magnetic Resonance Imaging Guided Interventional Procedure: Advance in clinical Application[J];China Comtemporary Medicine;2002-03
6 LU Jun-yan,TAN Ai-guo,JIANG Zhi-gang.Department of Clinical laboratory,Beijing Hospital Beijing 100730,China;The Study on the Serum Tumor Markers Used to Diagnose Lung Cancer[J];Journal of Chinese Physician;2001-11
7 Yang Xiao-wei (Department of internal medicine,Tianjin Tianhe Hospital, Tianjin 300050);Evaluation of Clinical Value of Combined Tumor Markers Detection in Diagnosis of Lung Cancer[J];Chinese Journal of Medicinal Guide;2003-04
8 WANG Zhi xin, GAO Ming fa (Oncology Center of PLA, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China);Clinical significance of carcinoembryonic antigen expression in non-small cell lung cancer[J];Acta Academiae Medicine Militaris Tertiae;2001-01
9 ZHENG Hang, HE Ben-fu, LUO Rong-cheng Department of Oncology, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China;Diagnostic value of combined detection of TPS,NSE and CEA in lung cancer[J];Journal of First Military Medical University;2003-02
10 XUE Chengyan, LI Min, SONG Ligang, SUN Lixin. Central Laboratory, Affiliated Hospital, Chengde Medical College, Chengde, Hebei 067000, P.R.China;Detection and diagnostic significance of carcinoembryonic antigen messenger ribonucleic acid in lung cancer tissues[J];Chinese Journal of Lung Cancer;2001-06
【Secondary References】
Chinese Journal Full-text Database 8 Hits
1 Xinlin MU,Zhancheng GAO,Ruanjian YE Department of Respiratory Medicine,Peking University People's Hospital,Beijng 100044,China;Correlation between Changes in Serum Level of CEA and CYFRA 21-1 and Objective Response of Chemotherapy[J];Chinese Journal of Lung Cancer;2009-09
2 Xu Junying,Liu Chaoying,Li Jiang,et al.Department of Oncology,Wuxi Municiple People's Hospital,Wuxi,Jiangsu(214023);Clinical Applicability of Determination of Serum Tumor Markers(CEA,CA15-3 and CA125) Levels Changes for Assessment of Efficacy of Chemotherapy in Patients with Breast Cancer[J];Journal of Radioimmunology;2009-02
3 FENG Xiaoshan,HAN Jing,GAO Shegan,et al.Department of Oncology,The First Affiliated Hospital of Henan University of Science and Technology,Henan Luoyang 471003;The relationship between 12 tumor markers and the progress of lung cancer[J];Hebei Medical Journal;2008-04
4 MENG Zhong-xue,ZHOU Qi-rong(Hospital of Youjiang Mining Bureau,Tiandong couty of Guangxi,Tiandong couty 531500 China);Application values of serum tumor markers detection in the diagnosis of lung cancer[J];Internal Medicine of China;2011-05
5 SUN Hong-ying1,FANG Fei1,ZHAO Lu-jing2,XING Guo-jie1,SHEN He-bai1△(1 college of life and environment sciences,shanghai normal university,shanghai,200234,China; 2 BIO-NANO THECHNOLOGY,Shanghai,201801,China);Joint Detection of Neuron-specific Enolase and Carcinoembryonic Antigen with Gold Immunochromatography Assay(GICA)[J];Progress in Modern Biomedicine;2011-07
6 Gui-ying Yan1,Zhen-ye Xu2,Hai-bin Deng2,Zhi-yong Wan1,Lei Zhang1,Jiao-yu Zhu31. Department of Oncology,Punan Hospital of Pudong New District,Shanghai 200125,China2. Department of Oncology,Longhua Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China 3. Department of Emergency,Shanghai TCM-integrated Hospital,Shanghai 200082,China;Effects of chemotherapy combined with Chinese herbal medicine Kangliu Zengxiao Decoction on tumor markers of patients with advanced non-small-cell lung cancer:a randomized,controlled trial[J];Journal of Chinese Integrative Medicine;2011-05
7 DUAN Hui-jie,HUANG Xiang-zeng (Department of MICU,Affiliated Tumor Hospital,Xinjiang Medical University,Urumqi 830000,China);Clinical significance of tumor marker CYFRA21-1 in patients with non-small cell lung cancer[J];Journal of Xinjiang Medical University;2009-02
8 MA Xiao-zhong,ZHANG Gen,SUN Rong-bing(Institute of Occupational Health of Dongfeng,Shiyai 442000,China);Analysis of measurement results of tumor marker in 1400 blood serums[J];Chinese Journal of Health Laboratory Technology;2010-12
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved