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《Chinese Journal of Cancer Prevention and Treatment》 2010-12
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Progress in research of preoperative radiotherapy for rectal cancer

YAN Hong-jiang,WANG Ren-ben Department of Radiation Oncology,Shandong Tumor Hospital,Jinan 250117,P.R.China  
OBJECTIVE:To review the research progress in preoperative radiotherapy for rectal cancer.METHODS:A total of 1 200 papers were searched with preoperative radiotherapy and rectal neoplasms as key words in Medline and CNKI databases from 1990-01 to 2009-10,and 34 papers were selected according to the included criteria:1)papers about rectal cancer indications of preoperative radiotherapy,advantages and disadvantages,and radiation pattern studies;2) papers about the significance of preoperative radiotherapy,side effects,predicting the sensitivity of preoperative radiotherapy,and preoperative chemoradiotherapy studies.RESULTS:The preoperative radiotherapy can shrink tumor volume,improve the resection rate of tumor,improve sphincter preservation rates,and reduce recurrence.The side effects of preoperative radiotherapy are mild.Compared with preoperative radiotherapy,preoperative chemoradiotherapy can further reduce the local recurrence rate and lower staging.CONCLUSIONS:Preoperative radiotherapy plays an important role in neoadjuvant therapy for rectal cancer.The problem how to stage precisely,select patterns of radiotherapy,as well as predict the sensitivity of preoperative radiation needs to be resolved urgently.
【CateGory Index】: R735.37
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 ZHANG Rong,XU Guo-liang,GAO Xiao-yan,LUO Guang-yu,LI Jian-jun,LI YinState Key Laboratory of Oncology in South China,Department of Endoscopy,Cancer Center,San Yat-sen University,Guangzhou 510060,P.R.China;Value of endoscopic ultrasonography in pre-operative staging of rectal carcinoma and after surgical resection in limited recrudesce[J];Chinese Journal of Cancer Prevention and Treatment;2009-18
2 WANG Zhong-zhao,ZHOU Zhi-xiang,BI Jian-jun,et al.(Cancer Hospital,Chinese Academy of Medical Sciences,Beijing 100021,China);An Analysis of Efficacy on Neoadjuvant Radiochemotherapy for 58 Cases with Locally Advanced Mid-Distal Rectal Cancer[J];Journal of Oncology;2009-01
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 HUANG Li ming,HU Bo nian CHEN Wei.Shaoxing People′s Hospital,Shaoxing,312000,P.R.China;The Observation of Local Recurrence relative Factors and Prevention of Rectum Cancer[J];Journal of Qilu Oncology;2001-01
2 XIA Li-jian Department of Gastrointestinal Surgery,Shandong Province Qianfoshan hoispital,Jinan 250014,P.R.China;Recent progress in treatment of local resection of rectal tumor[J];Chinese Journal of Cancer Prevention and Treatment;2008-13
3 Zhou Pinghong,Yao Liqing,He Guojie,et al Endoscopic Center,Zhongshan Hospital,Fudan University,Shanghai 200032 China;The Value of Ultrasonic Probe in the Pre-operative Staging of Colorectal Carcinoma[J];Chinese Journal of Ultrasound In Medicine;2002-02
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