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A STUDY ON ANTI-TUMOR EFFECTS OF ABALONE POLYSACCHARIDE(AP) FROM HALIOTIS DISCUS HANNAI INO

Xu Donghui Xu Shibo Wang Bing (Department of Pharmacy,Zhongshan University,Guangzhou 510275) Lin Yongcheng Shao Zhiyu (Department of Chemistry,Zhongshan University,Guangzhou 510275)  
The effects of abalone polysaccharide (AP) extracted from Haliotis discus hannai Ino on tumor inhibition were studied.AP did not exhibit cytocidal action on S 180 and HepA cells cultured in vitro. AP prolonged the survival time of the HepA mice and inhibited the growth of S 180 markedly.While inhibiting the growth of S 180 ,AP increased the weights of the thymus and spleen,decreased the level of Hepatic LPO in tumor bearing mice obviously.It was suggested that AP gave play to its anti tumor activity by increasing the immunity and anti oxidation of host.
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