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HU Chao qun, TAO Bao hua (South China Sea Institute of Oceanology, The Chinese Academy of Sciences, Guangzhou 510301, China)  
Vibriosis is one of the diseases damaging shrimps most. Its common symptoms are red leg, yellow or black gill, shell lesion, brown spot, cloudiness of abdominal muscle, larva luminescence. It is often accompanied by sepicemia. Vibrio parahaemolyticus is the firstly discovered Vibrio sp. Thereafter more than ten species such as V. anguillarum, V. alginolyticus, V. vulnificus, V. harveyi have been successively found. Although having been studied for more than 20 years, vibriosis' pathogensis is still not clear. Usually, antibiotics are used to treat the disease, but their effective scopes are narrow and a series of bad effects follows, especially they produce antibiotic resistant strains and cause environmental pollution. So it is imperative to probe into a new treating method. The immunological defense, which puts emphasis on improving shrimps' immunity, has no harmful effects and won't bring about the environmental problems. Vaccines against vibrios have achieved preliminary success, and the main routes of immunization include intra muscular injection, oral administrations, immersion and spray. Intra muscular injection is most effective but time taking, immersion and oral administration are following, while spray is rarely used because of its harm to shrimps. So it's important to find a suitable method to vaccinate. As to the shrimps' immunological research, the immune mechanism of shrimps is still unclear. It is commonly believed that immune of shrimps is mainly non special defense, in the process of which circulating haemocytes and prophanoloxidase system play an important role. This paper will try to summarize the present research status and trend of pathogens, pathology, diagnosis, immune mechanism and the defense of immunology.
【Fund】: 广东省自然科学基金重点项目!( 963029);; 中国科学院生命科学与技术研究特别支持项目!(Y982201)资助
【CateGory Index】: S945.1
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