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《Journal of Tropical Medicine》 2011-12
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Monitoring and analysis on vaccination reactions of the vaccines included in the National Immunization Program in Yangzhou in 2010

YANG Dong-mei,ZHU Dao-jian, HUANG Yao (Yangzhou Center for Disease Control and Prevention, Jiangsu,Yangzhou 225002, China)  
Objective To monitor the reactions associated with the vaccines included in the National Immunization Program. Method Monitoring data of vaccination reactions in Yangzhou were studied and analyzed by descriptive epidemiology. Results The vaccines included in the National Immunization Program performed in Yangzhou in 2010 were 11 kinds. 741 552 vaccinations were performed. 363 cases of vaccination reactions were reported, with an incidence rate of 4.90/10 000,and Jiangdu had the highest rate,6.77/10 000, while Kaifa had the lowest rate,3.31/10 000.The incidence rates were significantly different in different districts(χ2=25.17,P0.01).The highest incidence rate was 14.23/10 000 in July, and the lowest incidence rate was 1.32/10 000 in February. The incidence rates in different months had significant difference(χ2=163.99,P0.01). All the 11 kinds vaccines had the vaccination reactions reported,and the DPaT had the highest incidence rate , 13.49/10 000,while the PV had the lowest incidence rate, 0.46/10 000,and there were significantly differences of vaccination reaction incidence among different kinds of vaccines(χ2=365.44,P0.01).Fever was the main symptom of the common vaccination reactions. Among the adverse vaccination reactions, allergic skin rashes was the main symptom. The rate of the suspected vaccination reactions being reported within 24 hours, the investigation rate within 48 hours, the diagnostic classification rate and the standard handling rate were all 100%. Conclusions Yangzhou vaccination reaction monitoring system was perfect, and the vaccination reaction incidence rate was low. There were no statistical differences of abnormal vaccination reaction incidence among different districts, seasons, and genders. It was suggested to strengthen vaccination reaction monitoring, standardize immunization work and training, enhance our sense of responsibility, improve vaccination reaction response ability, and increase funds for handling vaccination reactions.
【CateGory Index】: R186
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