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Clinical significance of combined detection of CRP, BNP and cTnI in patients with acute myocardial infarction

YOU Zhi-gang;HUANG Lin;JIANG Xing-hua;Department of Cardiology, the Second Affiliated Hospital of Nanchang University;  
Objective To study the clinical significance of combined detection of high sensitive C reactive protein(hs-CRP),B type natriuretic peptide(BNP) and cardiac troponin I(c Tn I) for the diagnosis of acute myocardial infarction. Methods 193 cases of AMI patients in our hospital were selected for the study and their serum levels of hs-CRP, BNP and c Tn I were determined. Major adverse cardiovascular events and levels of three indices of hospitalization and follow-up analysis(MACE)relationship were analyzed. Results The average serum levels of CRP, BNP and CTn I were 8.35 mg / L, 267.67 pg / ml, and13.74 ng / ml, respectively. With the increase in the levels, the incidence of MACE was significantly increased(P0.01); the incidence of MACE of the patients with short duration of the disease was significantly more than patients with long duration of the disease(P0.05). Conclusion The levels of CRP, BNP and c Tn I and state of illness and prognosis are closely related.Detection of these levels can improve the diagnosis rate.
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