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《Chinese Journal of Radiological Health》 2008-02
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The Effects of Three Types of Macrophages Culture Supernatant on CFU-GM in Irradiated Mice

QUAN Hong-xun,FU Li,ZHAO Feng-chen,et al.Henan Medical College for Staff and Workers,Zhengzhou 450003 China.  
Objective To study the effects of peritional macrophyge(PM),alveolar macrophage(AM),and Kupffer cell(KC)on colony forming unite granulacyte/macrophage(CFU-GM)in irradiated mice.Methods Using techniques of hemopoietic progenitors in vitro,the authors studied the effects of three types of macrophages culture supernatant on CFU-GM.Results It is shown that three types of macrophages culture supernatant may stimulate proliferation and differentiation of CFU-GM in irradiated mice,and KC is the best one in comparison to others.Conclution three types of macrophages culture supernatant may protect CFU-GM irradiated mice with KC being the best method.
【Fund】: 河南省教育厅自然科学研究项目:2007310026
【CateGory Index】: R392
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