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Neuroactivities Basis of BA-JI-SU in Invigorating Kidney to Improve Mental Power

CHEN Jiewen, WANG Yong, TAN Baoxuan, CHEN Chaofeng (Dept. of Physiology, Guangzhou University of TCM, Guangzhou 510405,China)  
BA-JI-SU is a kind of monosaccharide extracted from Radix Morindae Officinalis. In this study, hippocampal slices of rats were employed to investigate the effects of BA-JI-SU on memory and neurons in anoxic condition and its mechanism. The results showed that BA-JI-SU could enhance the long_term potentiation(LTP),prolong the starting decreasing time and disappearing time of the amplitude of population spike(PS) in anoxic condition,increase the recovery rate after reoxygenation.Its mechanism was in relation with the level of nitric oxide(NO) in hippocampus. These results indicated that BA-JI-SU could increase the memory and protect neurons from anoxic injury. These supply experimental evidences for the clinical practice of BA-JI-SU.
【Fund】: 国家中医药管理局科研基金课题!编号: 97L025
【CateGory Index】: R285.5
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