Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《JOURNAL OF GUANGZHOU UNIVERSITY OF TRADITIONAL CHINESE MEDICINE》 2000-03
Add to Favorite Get Latest Update

Effect of Local Arterial Infusion of β_elemene on Breast Cancer Tissue Inhibition and Cell Apoptosis and Proliferation

TAN Min, GUO Zhitao, SHI Lingchun, WANG Bo, XIAO Chumei, ZHANG Weibing (The Second Affiliated Hospital, Guangzhou University of TCM, Guangzhou 510120, China)  
The effect of local arterial infusion of β_elemene on breast cancer tissue inhibition and cell apoptosis and proliferation was observed. The deoxyribonucleotide and labelling method mediating by end transferase and the immunohistochemical assay for cell nucleus antigen (PCNA)were employed to observe the apoptosis index (AI),cell division index and PCNA index. The mass of breast cancer was also observed.The breast cancer samples were taken from 14 cases receiving preoperative local arterial infusion of β_elemene (the treatment group) and 17 receiving operation only (control group ). The results showed that AI in the treatment group ( 7.97±1.50 ) was higher than the control group ( 2.26±0.49 ) (P 0.01 );the difference of PCNA index and division index were not significant between the treatment group ( 44.54±9.99 , 3.92±1.44 respectively) and the control group ( 42.80±6.78 ,3.88±1.08 respectively) (P 0.05 ). There is negative correlation between AI and the reduction of mass in the treatment group by degree relative analysis (r=_ 0.508 ).It is concluded that preoperative local arterial infusion of β_elemene can reduce the mass and its possible mechanism is by inducing breast cancer cell apoptosis.
【Fund】: 国家中医药管理局资助课题! (编号 :97Y0 2 8)
【CateGory Index】: R737.9
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 5 Hits
1 REN, Yun-Fenga,b CHENG, Kang-Mina,b LIU, Gui-Fenga,b SUN, Yan-Honga SHEN, Yu-Mei,a (a Radiopharmaceutical Centre, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800) (b Graduate School of the Chinese Academy of Sciences, Beijing 100049);Synthesis, Radiosynthesis and Anticancer Activity of β-Elemene Tricarbonyl Rhenium Complex[J];Acta Chimica Sinica;2008-04
2 JIA Xi-hua,TANG Han-jun~*,ZHAO Lian-chen,GENG Shu-mei(The First Central Hospital of Baoding City,Baoding,Hebei 071000,China);Antineoplastic and Anti-metastasizing Effects of Runing Ⅱ on Breas Cancer in Mice:An Experimental study[J];Clinical Misdiagnosis & Mistherapy;2006-06
3 LONG Kang-jian,HAN Feng-juan,WU Xiao-ke,WANG Xi-yue(No.1 Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine,Harbin Heilongjiang 150040);Effects of Zedoary Turmeric Oil Injection on SKOV3 Cell Proliferation and Pathological Morphological Changes in Ovarian Cancer[J];World Journal of Integrated Traditional and Western Medicine;2011-08
4 PU Lei1,ZHAO Shu-peng2(1.Liaoning Medical College,Jinzhou LIAONING 121001,China;2.Department of General Surgery,the First Affiliated Hospital of Liaoning Medical College,Jinzhou LIAONING 121001,China);Effects of zedoary turmeric oil on proliferation and apoptosis of human breast cancer cell MCF-7[J];Chinese Journal of New Drugs and Clinical Remedies;2009-05
5 XU Yi, Lu Bin, DING Zhishan, et al. Department of Gastroenterology, Zhejiang Hospital of Traditional Chinese Medicine, Hangzhou 310006, China;The extract of common turmeric induces apoptosis of gastric carcinoma cell line SGC-7901[J];Zhejiang Medical Journal;2004-07
【Citations】
Chinese Journal Full-text Database 3 Hits
1 Guo Zhitao,Yang Zhigang,Qin You,et al Guang Dong Provincial Hospital of T.C.M,Guangzhou (510120);Preoperative Super Intra arterial Continuously Infusion Chemotherapy with Embolization in the Treatment of Locally Advanced Breast Cancer[J];CHINESE JOURNAL OF SURGERY OF INTEGRATED TRADITIONAL AND WESTERN MEDICINE;1999-05
2 Gao Jiechun, Qian Baoping, Jin Baixiang. Department of Surgery, Children's Hospital, Shanghai Medical University, Shanghai 200032;The Effect of Preoperative Chemotherapy on Apoptosis and Proliferation of Neuroblastoma Cells[J];CHINESE JOURNAL OF PEDIATRIC SURGERY;1998-04
3 Zuo Yunfei,et al.;The Effect of Elemene on Induction Apoptosis of Ascites Hepatoma Cell Line HcaF25/CL16A3[J];PHARMACOLOGY AND CLINICS OF CHINESE MATERIA MEDICA;1998-02
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LIANG Guang,LI Xiao-kun,LIU Min,HUANG Zhi-feng (School of Pharmacy,Wenzhou Medical College,Wenzhou Zhejiang 325035);Progress on pharmacological properties of zedoary turmeric oil[J];Anhui Medical and Pharmaceutical Journal;2006-12
2 ZHOU Lin, AI Zhong li, LIU Zhi su,et al Department of General Surgery of the Second Affiliated Hospital of Hubei Medical University, Wuhan 430071, P R China;An in vitro study of effect of Kushen compound preparation on human colon cancer cell line SW480[J];CHINESE JOURNAL OF CANCER;2000-04
3 ZHANG Yuhong1) CHAI Weizhong2) ZHAO Jianxiong3)(1)The Hospital of Beijing Normal University,100875,Beijing,China;2)Public Health School of Peking University,100083,Beijing,China;3)Institute of Traditional Chinese and Western Integrated Medicine,Lanzhou University Medical College,730000,Lanzhou,China);FUZHENG-YILIU DECOCTION ON TUMOR CELL TELOMEREASE AND BLOOD VISCOSITY IN TUMOR-BEARING MICE[J];Journal of Beijing Normal University(Natural Science);2008-03
4 Zuo Yunfei,Zhang Yaozheng,Zheng Yun [WT5BX]Department of Laboratory,Dalian Medical University,Dalian,China;The study of the antitumor activity of elemene by flow cytometry(FCM)[J];JOURNAL OF DALIAN MEDICAL UNIVERSITY;2000-01
5 WANG Jin, YIN Jun-qiang, SHEN Jing-nan, JIA Qiang, HUANG Gang, JIN Song, ZOU Chang-ye Department of Musculoskeletal Oncology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China;In vitro screening of 32 traditional Chinese herbal extracts against U_2OS human osteosarcoma cells[J];Journal of Southern Medical University;2006-09
6 Xingqin ZHOU,Bin JI Department of Radiotherapy,Affiliated Hospital of Nantong University,Nantong 226001,China;Current Treatment of Brain Metastases from Lung Cancer[J];Chinese Journal of Lung Cancer;2009-10
7 Lu Bufeng, Yu Limin, Bian Chunxiang, Shao Shujuan, Zhu Zhengmei, Yang Peiman (Key Laboratory of Cellular and Molecular Biology of Liaoning Province, Dalian Medical University, Dalian 116027,China);EXPERIMENTAL STUDIES ON ANTI CANCER FUNCTION OF PIC-BE[J];CHINESE JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY;2000-01
8 Wei Wei, Luo-Sheng Tang, Li Li, Yi-Tao Yang, Wen-Jun Wang Department of Ophthalmology, Xiangya Second Hospital, Central-South University, Changsha 410011, Hunan Province, China;Effect of elemene and/or etoposide on the expression of survivin and apoptosis of retinoblastoma HXO-RB44 cells[J];International Journal of Ophthalmology;2007-01
9 YANG Chuanbiao XU KechengGuangzhou Fuda cancer hospital;Function of Anti-tumor of Chinese Medication[J];International Medicine & Health Guidance News;2004-18
10 Fang Ling, Cheng Daixong, Wang Haiyang. Cellular engineering Laboratory, Affiliated Hospital of Zunyi Medical College, Zunyi 563003;Early apoptosis of mice hepatoma HcaF cells induced by β-elemene[J];Guizhon Medical Journal;2001-12
China Proceedings of conference Full-text Database 1 Hits
1 Oncology Department, Beijing Hospital of TCM, Beijing, 100010 Wang Xiao-Min, Yang Guo-Wang;Progress of TCM Diagnosing and Treating of Lung Cancer[A];[C];2004
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 LI Ping,ZHANG Mei (Dept.of TCM,Anhui Provincial Hospital,Anhui Hefei 230001,China);EFFECTS OF ASTRAGALUS ON APOPTOSIS RELATED GENE EXPRESSION IN RATS AFTER CEREBRAL ISCHEMIA[J];Journal of Anhui Traditional Chinese Medical College;2001-04
2 CHEN Rui chuan, SU Jin hua, MA Sheng ping, et al Cancer Research Center of Xiamen University, Xiamen 361005, P R China;Induction of human gastric cancer MGC 80-3 cell apoptosis by photoactivated curcumin[J];CHINESE JOURNAL OF CANCER;2000-04
3 ZHOU Jun min, CAO Jian guo, LIAO Duan fang Department of Pharmacology, Hengyang Medical College, Hengyang 421001, P R China;Effects of etoposide on growth proliferation and apoptosis in human HIC/S cells[J];CHINESE JOURNAL OF CANCER;2000-04
4 ZHOU Lin, AI Zhong li, LIU Zhi su,et al Department of General Surgery of the Second Affiliated Hospital of Hubei Medical University, Wuhan 430071, P R China;An in vitro study of effect of Kushen compound preparation on human colon cancer cell line SW480[J];CHINESE JOURNAL OF CANCER;2000-04
5 RONG Yu* , LIANG Fu you, CHEN Li, DU Hai jun, LIU Le yao, SUN Hong liu, AN Wei Department of Cell Biology, Capital University of Medical Sciences, Beijing 100054, P.R.China;Norcantharidin induces apoptosis in human breast cancer cell line[J];Chinese Journal of Cancer;2000-12
6 TU Shui ping* , JIANG Shi hu, QIAO Min min, WANG Li fu, ZHANG Shu, YUAN Yao zong, WU Yun li,WU Yu xin. Department of Gastroenterology, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025,P.R.China;Induction of apoptosis by trichosanthin in gastric cancer cell MKN-45[J];Chinese Journal of Cancer;2000-12
7 MA Jing1, FU Nai yang2, LI Yu mei3, PENG Wen lie1, XU An long1*1.Department of Biochemistry and Center for Biopharmaceutical Research, College of Life Science, Zhongshan University, Guangzhou 510275, P.R.China2.Institute for Drug Control of Guangdong;Glycyrrhiza uralensis Fisch Extract Selectively Induces Apoptosis in Several Human Cancer Cell Lines in Vitro[J];Chinese Journal of Cancer;2001-08
8 SI Wei ke*, GAO Li hong, LIU Bing, CHENG An, LI Peng, YAO JieDepartment of Clinical Biochemistry, the Third Military Medical University, Chongqing 400038, P.R.China;Regulation of G_1 Phase Cell Cycle Regulation Factors in Differentiation and Apoptosis of Matrine Induced Hepatoma Cells[J];Chinese Journal of Cancer;2001-08
9 YANG Ping, YU Ting xi, MA Run di, YU Li jian*, SU Wei ming, SHAO Hai yan, LIAO Ming neng, HUANG Lai zhen Guangdong Provincial Key Laboratory of Marine Pharmacy,Zhanjiang Ocean University, Zhanjiang 524025,P.R.China;Cell Cycle Arrest and Apoptosis Induced by Tubeimoside in HeLa Cell[J];Chinese Journal of Cancer;2002-04
10 DING Xue qiang1*, WANG An xun1, KONG Qing yu2, CHEN Hui zhi3, CHEN Yu11 Department of Stomatology,The First Affiliated Hospital,Sun Yat sen University ,Guangzhou 510080,P.R.China2 Department of Medicine,The First Affiliated Hospital,Sun Yat sen Un;Anticancer Effect of Hydroxycampothecin on OralSquamous Carcinoma Cell Line[J];Chinese Journal of Cancer;2002-04
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 LIANG Guang,LI Xiao-kun,LIU Min,HUANG Zhi-feng (School of Pharmacy,Wenzhou Medical College,Wenzhou Zhejiang 325035);Progress on pharmacological properties of zedoary turmeric oil[J];Anhui Medical and Pharmaceutical Journal;2006-12
2 JIN Hai-feng1,LV Bin1,CHEN Zhe1,MA Zhong-jun2(1He Frist Affi liated Hospital,Zhejiang Chinese Medical University,Hangzhou 310006,China;2College of Pharmacy,Zhejiang University,Hangzhou 310058,China);Effect of diterpenoid C from Radix Curcumae on proliferation of human gastric cancer cells SGC-7901[J];China Journal of Traditional Chinese Medicine and Pharmacy;2010-05
3 JIN Hai-feng1,LV Bin1,CHEN Zhe1,MA Zhong-jun2,WANG Lou-Lei3(1The First Affiliated Hospital,Zhejiang Chinese Medical University,Hangzhou 310006,China;2College of Pharmacy,Zhejiang University,Hangzhou310058,China;3The First Affiliated Hospital of Medical School of Zhejiang University,Hangzhou 310003,China);Influence of diterpenoid curcumrinol C from ether extract of Radix Curcumae on human gastric cancer cell SGC-7901 in expression of Caspase-9,3,7,and PARP(89KD)[J];China Journal of Traditional Chinese Medicine and Pharmacy;2011-02
4 DOU Yu-qin1, LIU Yu-xin1, YAN Hui-fang2, LU Hong-qi2 (1. Dalian Institute of Medical and Pharmaceutical Sciences, Dalian 116013, China; 2. Laboratory of Pharmacology, Shanghai Institute of Pharmaceutical Industry,Shanghai 200437, China);Anti-tumour activity of concentrated elemene injection in vitro[J];Journal of Dalian Medical University;2005-06
5 XU Tao,XU Rui-an(Institute of Molecular Medicine,Huaqiao University,Quanzhou 362021,China);Progress on Ati-Tumor Mechanism of Chinese Medicine and Its Active Ingredients[J];Journal of Huaqiao University(Natural Science);2009-04
6 Zhang Shujia,Zhou Peng,Duan Huaxin,Yuan Han(Key Laboratory of Bioorganic Chemistry of Liaoning Province,College of Environment Science and Chemical Engineering,Dalian University,Dalian 116622);Progress of β-Elemene and its Derivatives[J];Chemistry;2010-06
7 ZHAN Xiao-ri1,ZENG Zhao-wu1,MENG Fan-li2,WANG Shu-ling1,XIE Tian1(1.Center of Biomedicine and Health,Hangzhou Normal University,Hangzhou 311121,China; 2.College of Medicine and Health Management,Hangzhou Normal University,Hangzhou 310036,China);Pharmaceutical Researches on Zedoary Turmeric Oil[J];Journal of Hangzhou Normal University(Natural Science Edition);2011-05
8 JU Jian-feng,YU Wei-ping,FU Chun-sheng,MA Li-ming1(Teaching Hospital of Shangdong University of Traditional Chinese Medicine,Ji′nan 25011;1.Shandong Institute of Pharmaceutical Industry,Ji′nan 250100);Modern research and clinical application of β-elemene[J];Qilu Pharmaceutical Affairs;2008-09
9 SONG Jinxin,LI Guorong Key Laboratory of Animal Resistant Biology of Shandong Province,College of Life Science,Shandong Normal University,Ji’nan 250014,China;The mechanism of tumor suppressor gene DLC1 in breast cancer[J];Chemistry of Life;2011-02
10 CAI Yu, FENG Xiaozhen;THE ACTUALITY OF RESEARCHING THE REVERSION OF MULTI-DRUGS RESISTANCE OF TUMOR WITH CHINESE TRADITIONAL MEDICINE[J];Modern Hospital;2007-01
China Proceedings of conference Full-text Database 1 Hits
1 LI Xiang-qi (the Affiliated Hospital of Taishan Medical College,Tai-an 271000,China);Effects of Zedoray Turmeric Oil oil on Fas/FasL expression of rats breast cancer precancerous lesions tissue[A];[C];2011
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved