Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
Add to Favorite Get Latest Update

Anti_HBV Effect of Phyllanthus Simplex Extracts in Vivo and in Vitro

HUANG Zhengchang, DENG Xuelong, ZHU Yutong, ZHANG Meiyi, LIU Ni, LI Fengxian (Tropical Medicine Institute, Guangzhou University of TCM, Guangzhou 510405, China)  
Anti_HBV effect of water extract and alcohol extract of Phyllanthus simplex Retz. from Taiwan was investigated in vivo and in vitro by means of 2215 cell strain and duckling infected with DHBV. The results showed that the water extract and alcohol extract had a certain inhibitory effect on HBsAg, and the alcohol extract showed no inhibitory effect on HBeAg. In vivo, the water extract at the dosage of 10g.kg -1 .d -1 and 5g.kg -1 .d -1 had an obvious inhibitory effect on DHBV_DNA on the fifth and the tenth day during treatment and the third day after treatment, while the alcohol extract showed no above effect. It is indicated that the water extract of Phyllanthus simplex Retz. exerts an anti_HBV effect.
【CateGory Index】: R285
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 6 Hits
1 LI Xiu-li~1,YE Feng~2, YU Teng-fei~3(1.Medical School of Chifeng College,Chifeng,Inner Mongolia 024000,China;2.Institute of Materia Medica,Chinese Academy of Medical Sciences,Beijing 100050,China;3.Pharmacetical School of Inner Monglia Medical College,Huhehaote 010000,China);Research Advancement on Pharmacological Effects of Phyllanthus emblica[J];LiShiZhen Medicine and Materia Medica Research;2006-02
2 ZHANG Jun feng,TAN Jian,LIU Ying hua,MENG Yi wen ( Chendu Institute of Biology,Chinese Acedemy Science ,Chengdu 610064,China);ADVANCE IN THE RESEARCH OF HERBS AND NATURAL PRODUCTS ON ANTIVIRAL AGAINST HEPATITIS B VIRUS[J];Natural Product Research and Development;2002-04
3 ZHANG Chao*,LUO Min,LING Qing-zhi,CHEN Tian-yi.*Medical College,Anhui University of Science and Technology,Huainan,Anhui 232001,China;Therapeutic effects of polysaccharide from B.Jiangsiensis against hepatitis B virus in vivo and vitro[J];Chinese Journal of Primary Medicine and Pharmacy;2006-04
4 LIANG Chen-yan ,ZHEN Han-shen ,MA Wen-Fang ,LIU Yuan-yuan, CHEN Mei-an (Guangxi Chinese Traditional Medical University,Nanning ,530001);RP-HPLC Determination of Quercetin and Kaempferol in the Leaves of Phyllanthus emblica L[J];Chinese Journal of Experimental Traditional Medical Formulae;2010-08
5 MAO Jian;LIU Zhen-jie;Department of Clinical Pharmacy,People′ s Hospital of Fuchuan County in Guangxi Zhuang Autonomous Region;Child Care Center,Institute of Medicinal Plant Development in Guangxi Zhuang Autonomous Region;;Simultaneous measurement of quercetin content and kaempferol content in Phyllanthus emblica leaf based on HPLC[J];China Modern Medicine;2014-19
6 MAO Jian;LIU Zhen-jie;Department of Clinical medicine,People′s Hospital of Fuchuan County in Hezhou City of Guangxi Zhuang Autonomous Region;Conservation Center,Guangxi Institute of Medicinal Plant,Guangxi Zhuang Autonomous Region;;Study on HPLC fingerprint analysis of Phyllanthus emblica L[J];China Modern Medicine;2014-17
Chinese Journal Full-text Database 1 Hits
1 Liu Zhuang, Fu Xixian, Zhang Nailin, et al. The First Teaching Hospital, Beijing Medical University 100034;The inhibitory effect of Chinese herb Phyllanthus on hepatitis B Virus in vitro[J];CHINESE JOURNAL OF EXPERIMENTAL AND CLINICAL VIROLOGY;1997-03
Chinese Journal Full-text Database 10 Hits
1 WEI Ti-man1,YU Jie2,YU Si-jiu1,XING Xiao-ling2,QIN Feng2,HONG Wei-ming2,WANG Da-da2,ZHU Zheng-sheng1 1.College of Veterinary Medicine,Gansu Agricultural University,Lanzhou 730070;2.Animal Pharmaceutics Department,Jiangsu Animal Husbandry & Veterinary College,Taizhou 225300;Screening of Anti-Newcastle Disease Virus Ingredients of Phyllanthus urinaria[J];畜牧与饲料科学(英文版);2009-02
2 WEI Ti-man et al(College of Veterinary Medicine,Gansu Agriculture University,Lanzhou,Gansu 730070);Screening of Anti-Newcastle Disease Virus Ingredients of Phyllanthus urinaria[J];Journal of Anhui Agricultural Sciences;2009-18
3 ZHANG Xiao-bin et al(Department of Biomedical Engineering,Shangluo University,Shangluo,Shaanxi 726000);Investigation of Phyllanthus Plants Resources in Qinling Mountains[J];Journal of Anhui Agricultural Sciences;2011-06
4 LAN Jun-feng et al(Department of Chemistry and Life Science,Liuzhou Teachers College,Liuzhou,Guangxi 545004);Optimization of Extraction Process of Flavonoids from Phyllanthus urinaria L. by Response Surface Methodology[J];Journal of Anhui Agricultural Sciences;2011-20
5 Yu Miao, Harbin Phamaceutical Group R & D Center(150020);Test the Remaining Content of Calf Serum in Recombinant Human Erythropoietin(EPO)by Reverse Indirect Hemaggltination[J];Heilongjiang Medical Journal;2002-03
6 CHEN Guang-ying HAN Chang-ri SONG Xiao-ping WEN Li-jun CHEN Lai-guo(Department of Chemistry,Hainan Normal University,Haikou 571158,China);THE RESOURCES AND CURRENT EXPLOITATION OF THE GENUS PHYLLANTHUS IN HAINAN PROVINCE[J];Journal of Hainan Normal University(Natural Science);2000-01
7 Chen Zhengtu 1 Zhu Yutong 1 Fang Hongxun 2,et al. 1.Tropical Medicine Institute Guangzhou University of TCM 510407 2.City University of Hongkong;A Study on the Anti_HBV Activity of Three Kinds of Phyllanthus Plant in Vitro[J];JOURNAL OF GUANGZHOU UNIVERSITY OF TRADITIONAL CHINESE MEDICINE;1997-02
8 JIANG Jingrong,ZHANG Tianhong,ZHONG Sen△(Department of Infectious Diseases,Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610000,China);Clinical Application and the Mechanism of Phyllanthus for Chronic Hepatitis B[J];Journal of Practical Traditional Chinese Internal Medicine;2013-04
9 He Langchong, Qi Lin, Lu Juxian and Niu Xiaofeng(Department Of Pharmacy, Xi'an Medical University, Xi'an 710061);harmaceutical developing of Shaanxi phyllanthus urinaria L.Ⅲ Inactivation of HBV antigen in vitro by theextracts and constituents[J];NORTHWEST PHARMACEUTCAL JOURNAL;1996-01
10 ZHANG Wei, WANG Yu-qun, JI Guang, XING Lian-jun, ZHANG Guang-ye (Longhua Hospital Affiliated of Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China);Pharmacodynamics study of Qihuang granula on anti-virus of 2.2.15 cells in vitro[J];Modern Jorunal of Integrated Traditional Chinese and Western Medicine;2005-09
Chinese Journal Full-text Database 10 Hits
1 Gao Ling,Wang Yixian,Zhang Qinfen Jiangsu Institute of Cancer Research,Nanjing 210009;ANTITUMOR EFFECT IN VITRO OF TRADITIONAL CHINESE MEDICINE 901[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;1997-04
2 Sheng Wan mei1 et al.(1Changzhou Technical Institute of Tourism &Commerce,Jiangshu,Changzhou,213000;2 Department of Chemistry Engineering,Huainan Union University,Huainan,232001);Study on Antioxidation of Total Falvones from Pom Egranate Leaf[J];Anhui Agricultural Science Bulletin;2008-21
3 XIAO Lin et al (Chemistry and Chemical Engineering School,Shanghai Jiaotong University,Shanghai 200245);Application of Enzyme Method for Extracting Botanic Ingredient[J];Journal of Anhui Agricultural Sciences;2006-08
4 LI Li et al (Huanghuai University,Zhumadian,Henan 463000);Research on the Determination of the Anti-oxidability of Apple Polyphenol[J];Journal of Anhui Agricultural Sciences;2006-21
5 ZHU Deng-xiang et al(Experimental Center,Hebei North University,Zhangjiakou,Hebei 075000 );Study on the Extraction Technology of Polyphenol Substances from Grape Seeds[J];Journal of Anhui Agricultural Sciences;2008-17
6 LV Qun-jin et al (Food College,Shanghai Ocean University,Shanghai 201306);Study on the Extraction Technologies of Polyphenols from Carambola Dregs by Microwave Method[J];Journal of Anhui Agricultural Sciences;2009-15
7 Xie Bingfen Liu Zongchao Hao Donglei, et alCancer Institute, Sun Yat Sen University of Medical Sciences, Guangzhou, 510060;The studies of cytotoxic effect and antitumor effect by TP[J];CHINESE JOURNAL OF CANCER;1998-06
8 Zhang Junwei Bao Manzhu Chen Longqing (Department of Forestry, Huazhong Agricultural University, Wuhan,430070,P.R.China);Analysis of Prunus mume, P.persica, P.salicina, P.armeniaca, P.subhirtella and P.lannesiana by RAPD[J];JOURNAL OF BEIJING FORESTRY UNIVERSITY;1998-02
9 GAO Shi qi 1△ ,CHI Bao rong 1,WANG Feng 2,LIU Xiao dong 3,JIN Zhen xun 2,HE Hong 2 (1. Dept.of Digestive Disease,The First Hospital,Jilin University,Changchun 130021,China; 2. Dept.of Infectious Disease,The First Hospital,Jilin University; 3. Dept.of Radiobiology, School of Public Health,Jilin University);Effect of the Extract of Syringa on the Secration of HBsAg and HBeAg in HepG2.2.15 Cells[J];Journal of Jilin University of (Medicine Edition);2003-04
10 Cheng Mingliang et al. (Affiliated Hospital of Guiyang Medical College, Guiyang);Clinical and Experimental Study of Treatment of Chronic Hepatitis B with “Yigansan”[J];China Journal of Traditional Chinese Medicine and Pharmacy;1997-03
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 CHENG Xiao-mei et al (Southwest Jiaotong University School of Life Science and Engineering,Chengdu,Sichuan 610031);Research Progress on Phyllanthi fructus[J];Journal of Anhui Agricultural Sciences;2010-24
2 YIN Ying-song,CHEN Si-ping,ZHAO Gui-qin(Institute of Chinese Mateia Medica,Chengde Medical College,Hebei Chengde 067000,China);STUDY ON INTERNAL STANDARD AND CHROMATOGRAPHIC CONDITION IN DETERMINATION OF OLEUROPEIN CONTENT BY HPLC[J];Journal of Chengde Medical College;2011-04
3 DONG Kun1,LI Chang-Wei2,QU Hui3,ZHAO Jing-Nan41Northwestern Polytechnical University,Xi'an 710072,China,2Shanghai University of Sport,Shanghai 200438,China,3Engineering College of Armed Forces,Xi'an 710086,China,4Xi'an Military Academy,Xi'an 710108,China;Effect of phyllanthus emblica L on the expression of protein kinase B and glucose transporter4 mRNA in the skeletal muscle of insulin resistance rat[J];Journal of the Fourth Military Medical University;2009-21
4 Fu Ruo-nong(Depertment of Chemistry,Beijing Institute of Technology);The advances of gas chromatography in recent two years[J];Chinese Journal of Analysis Laboratory;2011-05
5 XU Rong,GUO You-hong,HUANG Qing-ru(Department of Pharmacy,Quanzhou Medical College,Quanzhou 362000,China);The Research of Phyllantthus emblica L.[J];Strait Pharmaceutical Journal;2012-01
6 CHEN Jia 1,XU Zhaofa 1,OUYANG Hongtao 2,PENG Minyuan 3,WU Ting 1,LIU Jing1,LIU Yanping 1,YAN Huiwen 1(1.School of Biological Science and Technology,Central South University,Changsha 410013;2.Second People's Hospital of Hunan Province,Changsha 410007;3.Department of Hematology,Xiangya Hospital,Central South University,Changsha 410008,China);Effect of extracts from Radix Trichosanthis on the expression of HBsAg and HBeAg in HepG2.2.15 cells[J];Journal of Central South University(Medical Science);2012-01
7 Xi Xiaorong,Xing Haijing,Zhao Wenjuan,Peng Jing,Han Niping(yunnan college of basic medicine,kunming,yunnan 650500);Compound Phyllanthus emblica Streptococcus throat lozenges and the population of saliva SIgA[J];Guiding Journal of Traditional Chinese Medicine and Pharmacy;2010-12
8 Wang Min,Wang Weimin,Chen Liang (College of Food Science,Guangdong Ocean University,Zhanjiang,Guangdong 524025,China);Determination of the Total Content of Flavonoid in Golden Mango Offal[J];Academic Periodical of Farm Products Processing;2006-12
9 QIN Shuai-ji,LUO Su-qin,ZHANG Zhen-tao,et al. (Inner Mongolia Medical College,Hohhot 010059 China);THE RESEARCH ON ANTI-HEPATITIS B VIRUS DRUGS[J];Acta Academiae Medicinae Neimongol;2010-S3
10 GUO Yun-ping,YANG Shuo,YIN Rui,YAO Jian-ju,YANG Rong-jun,LIU Bo(School of Pharmaceutic Science and Yunnan Key Laboratory of Pharmacology for Natural Products,Kunming Medical University,Kunming Yunnan 650500,China);Study on the Content of Total Flavonoid and SOD Activity in Fructus Phyllanthi[J];Journal of Kunming Medical University;2012-06
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved