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《Journal of Guangzhou University of Traditional Chinese Medicine》 2002-02
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Effect of Xinmaitong Capsule on Serum Level of Vascular Endothelial Growth Factor

MENGJun, FENG Jun , QIU Ruixiang, LAN Jim, HE Jingbo(1. Dept. of TCM, First Affiliated Hospital, Sun Yat-sen University of Medical Sciences, Guangzhou 510080, China;2. Dept. of Angiocardiopathy, Dongguan Shilong People's Hospital, Dongguan 523321, Guangdong, China;3. Dept. of TCM, Shenzhen Baoan People's Hospital, Shenzhen 518000, Guangdong, China)  
[ Objective] To explore the effect of Xinmaitong capsule on the expression of vascular endothelial growth factor (VEGF) in patients with acute myocardial ischemia (AMI). [Methods] Forty-six cases of AMI were randomly allocated to Group A (n = 23, treated with routine treatment combined with Xinmaitong capsule) and Group B (n = 23 cases, only routine treatment) . Serum VEGF level in different time before and after percutaneous transluminal coronary angio-plasty (PTCA) was examined. [Results] There is a significant difference between two groups. Serum VEGF level in Group A after a week of treatment differed that in Group B (P 0.05). [Conclusion] Xinmaitong capsule can promote the expression of VEGF and induce neo-vascular formation.
【CateGory Index】: R259.4
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