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《Journal of Guangzhou University of Traditional Chinese Medicine》 2015-06
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Study on Chemical Constituents of Flavonoids from Laggera pterodonta(DC.) Benth.

LI Tiantian;LI Jing;YU Haofei;YANG Zifeng;HUANG Qinghui;MA Hongxia;WANG Xinhua;ZHANG Rongping;School of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Natural Products , Kunming Medical University;State Key Laboratory of Respiratory Disease , the First Affiliated Hospital of Guangzhou Medical University;Kunming Biomedical Engineering Research Center;  
Objective To study the chemical constituents of Laggera pterodonta( DC.) Benth.. Methods Various chromatographic methods were applied to isolate and purify the ethnol extract of the aerial parts of Laggera pterodonta. Their structures were identified by chemical and spectral analysis. Results Six flavonoids were obtained and their structures were elucidated as 5,6-dihydroxy-3,7,4'-trimethoxyflavone(1), artemitin(2),casticin(3), 5,4'-dihydroxy-6,7-dimethoxyflavone(4), penduletin(5) and chrysosplenetin B(6). Conclusion Compounds 1, 3 and 4 were isolated from the plant for the first time.
【Fund】: 国家地区自然科学基金资助项目(编号:81460593);; 云南省重点项目(编号:2014FA031);; 云南省科技厅—昆医联合专项(编号:2015FB003)
【CateGory Index】: R284.2
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