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《China Dairy Industry》 2002-03
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The state of the art on the mechanisms of lactic acid bacteria in reducing chole sterol

HAN Jun-hua1,SHENG Xiao-gan2,DONG Cai-feng1,GE Chun-mei1,ZHANG Bo-lin1(1.Hebei Agricultural University,Baoding 071001,China;2.Howell Biotechnology Co.Ltd.,Lanzhou 730070,China)  
Ever-growing evidences in vivo and in vitro have shown that administ ration of lactic acid bacteria(LAB)preparations and related products are able to reduce serum cholesterol,offering potential benefits to hypercholesterol indivi duals.However,the three different mechanisms by which LAB induced the lowing of cholesterol have been established due to the diverse scientific reports from bot h at home and abroad.They are:1assimilation of cholesterol;2de-conjugation of b ile salts;3other mode of action like inhibiting the key enzymes required for bi osynthesis of cholesterol.Some problems associated with research into the decrea se of cholesterol by LAB were also considered.
【Fund】: 国家教育部归国留学人员基金
【CateGory Index】: TS252.1
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