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《Foreign Medical Sciences Section of Maternal and Child Health》 2004-05
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Progress in study on fetal cell-free nucleic acid in maternal peripheral blood

JIA Yi-fang,WU Ai-hua,ZHANG Ai-dong (Key Laboratory of Eugenic Technique, Shandong Provincial Research Institute for Family Planning,Shandong Jinan 250002,China)  
Noninvasive prenatal diagnosis is a long-sighted goal of human genetics. The fact that fetal DNA can be found in noncellular fractions, i.e.plasma and serum of maternal peripheral blood provides a possibility to perform noninvasive prenatal diagnosis .The subsequent development of real-time quantitative PCR technique has allowed close to 100% of sensitivity and specificity for fetal DNA detection in maternal plasma/serum. Meanwhile, this technique also has developed a detection for fetal RNA and fetal epigenetic markers from maternal plasma.
【CateGory Index】: R714.5
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【Co-references】
Chinese Journal Full-text Database 6 Hits
1 Shi-xiu LIAO 1* , Fei-fei HUANG 2, Yan-li YANG 2, Zi-bo SONG 2, Ying-tai WANG 2, Zhao-cai WANG 2, Xian-zhong QU 3, Han-ping CHEN 1△ (1.Department of Gynecology and Obstetrics,Affiliated Tongji Hospital,Tongji College,Huazhong University of Technology,Wuhan 430030,China;2.Medical Genetics Institute ,the People’s Hospital of Henan Province;3. Department of Ultrasound, the People’s Hospital of Henan Province);Screening for chromosomal abnormalities using nuchal translucency measurement with materal serum biochemistry markers in first trimester[J];Journal of Peking University(Health Sciences);2005-01
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1 WU Qing-ming1,ZHOU Jin2,LIU Wei1,WANG Rui3,YANG Liu3,YU Liang-kuai 2 (1 Medical College of Shihezi University Shihezi, Xinjiang 832000, China 2 Department of Obstetrics&Gynecology, Urumuqi General Hospital of Lanzhou Military region, Urumuqi 830000, China 3 Station of cliniccal research, Urumuqi General Hospital of Lanzhou Military region, Urumuqi 830000, China);Result Analysis of 1641 Prenatal Screening and 95 Prenatal Diagnosis in Second Trimester[J];Progress in Modern Biomedicine;2010-14
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