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《Foreign Medical Sciences Section of Maternal and Child Health》 2005-04
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Comparison of phytoestrogens therapy with hormone replacement therapy

ZHANG Yan, HU Ya-li(Department of Gynecology and Obstetrics, The Affiliated Drum Tower Hospital of Nanjing University, Jiangsu Nanjing 210008, China)  
Large amount of evidences over the past decade proved that risks caused by HRT overwhelm any benefits of it. Phytoestrogens, such as soy isoflavones and red clover products and/or cimicifuga racemosa(CR), are newly found selective estrogen receptor modulators(phyto-SERMS). In this article, we discussed their mechanisms of action and reviewed the literatures on effect of these bio-active compounds. They exert benificial roles in improvement of postmenopausal symptoms such as hot flash, prevention of osteoporosis and urinary incontinence. But meanwhile, they increase risks of heart disease, breast cancer and endometrial cancer. Furthermore, whether they influence the cognitive function and fertile ability is controversial till now.
【CateGory Index】: R458.7
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