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《Journal of Sichuan University (Natural Science Edition)》 2005-06
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The Research on the Inhibiting Tumor Effect of D.denneanum in Vivo

LUO Ao-xue~(1,2,3),SONG Guan-bin~(1,3),FAN Yi-jun~1,LUO Aoshuang~3,CHUN Ze~(2)(1.College of Bioengineering,Chongqing University,Chongqing 400044,China;2.Chengdu Institute of Biology,Chinese Academy of Sciences.Chengdu 610041,China;3.Department of Resources and Environment,Sichuan Agriculture University,Sichuan Dujiangyan 611830,China;4.College of Life Science,Sichuan University,Chengdu 610064,China)  
To explore the inhibiting tumor effect of D.denneanum in vivo.The tumor S180 loading mouse model was established.Investigated the antitumor activity of D.denneanum by observing the tumor、spleen and thymus weight of these mice after administrating the drug for 10 days.Results: The ratio of inhibiting tumor of polysaccharides are over 50%,the ratio of inhibiting tumor of ethanol extracts are 64.81%,57.26%.Compared with the positive group,the index of spleen and the index of thymus of polysaccharides have obviously rise.Conclusion: The polysaccharides of D.denneanum can inhibiting tumor and advance immunity of mouse bearing tumor.The ethanol extracts of D.denneanum can inhibiting tumor too,and can advance immunity of mouse bearing tumor in some degree.
【Fund】: 四川省重点科技攻关项目(04NG001-022-4)
【CateGory Index】: R285
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