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《Journal of Fisheries of China》 2002-04
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The effect of environmental stress to fish immune system

WANG Wen-bo, LI Ai-hua ( State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences , Wuhan 430072, China )  
Environmental stress can increase the plasma cortisol level of fish and long - term elevation of this hormone in plasma would inhibit immune function, hurt immune organs, increase the susceptibility of fish to pathogens. The numbers of fish lymphocytes decrease after cortisol administration. But when neutrophils, macrophages, non-specific cytotoxic cells, antibody-producing cells and plague-forming cells are concerned, the stress or cortisol administration may activate or restrain their activities. Humoral immune factors, such as lysozyme and complement of fish, are often suppressed by environmental stress. When fish encounter stress, some parts of immune system of fish may be suppressed immunologically, while the others boosted up as compensation to overcome the stress.
【Fund】: 中科院生物学及生物技术特别支持费(2001);; 中国科学院水生生物研究所知识创新工程领域前沿项目
【CateGory Index】: X174
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