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《JOURNAL OF SICHUAN CONTINUING EDUCATION COLLEGE OF MEDICAL SCIENCES》 1999-03
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The Experimental Study on L cell Regulate Hematopoiete Effected by IL 1

Huang Xiaoqin,Zhu Bide∥Sichuan Continuing Education College of Medical Science,Cheng du 610041  
Objective:To explore the relationship between IL 1 and L cell in hematopoiesis,provide experimental fact to theory of stramal cell regulate hematopoiete.Methods:Use L cell conditioned medium induced by different concentration IL 1(LcCM IL 1 )or not (LcCM) as well as LcCM and IL 1 (LcCM+IL 1) in stead of exogeneous hematopoitic growth facter in hemato poitic progenitor culture in vitro,then compare the progenitor colony numbers.Results:The numbers of progenitor colony in group of LcCM were:CFU GM:52±8.4,BFU E:34±6.6,CFU E:100±13,in the group of LcCM IL 1 were CFU GM:24±7.5,BFU E:32±6.3,CFU E:146±11.2,the P 0.05 in CFU GM and CFU E.In the group of LcCM+IL 1,the numbers were CFU GM:54±8.9,BFU E:31±5.9,CFU E:121±12.4,all the P 0.05 compared with the group of LcCM.Conclusion:IL 1 can induce L cell produce hematpoitic inhibit facter witch inhibit CFU GM only and hematopoitic growth facter which stimulate CFU E.There is no cooperation between IL 1 and the hematopoietic regulate facter which produce by L Cell,The effection of IL 1 on Fibroblast regulate hematopoiete was different as diffrent source of Fibrblast.
【Fund】: 国家自然科学基金
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【Citations】
Chinese Journal Full-text Database 3 Hits
1 Guo Ruiqing, Zhu Bide~* (The Second Affiliated Hospital of Qingdao Medical College, Qingdao, Chongqing University of Medical Science, Chongqing~* );THE EFFECT OF PERITONEAL MACROPHAGE CULTURE SUPERNATANTS ON MOUSE HEMOPOIESIS[J];Acta Anatomica Sinica;1992-03
2 Huang Xiaogin Zhu BideDepartment of Anatomy, Sichuan Continuing EducationCollege of Medical Sciences, Chengdu 610041;An Experimental Study on L-cell HRF Induced by TSPG[J];Sichuan Journal of Auatomy;1998-04
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【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Xia Tian Jiang Dezhao(Research Laboratory of Blood Physiology, Hunan Medical University, Changsha 410078);Culture of murine HPP-CFC in vitro using conditioned mediumsubstitute for recombinant growth factors[J];BULLETIN OF HUNAN MEDICAL UNIVERSITY;1998-02
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3 ;Effect of Mononuclear Phagocyte on Hemopoiesis[J];Henan Medical Research;1997-03
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8 FU Li1), ZHANG Yuming2) ,LIU Jianfeng1),HAN Fen1),LIU Lu1),QUAN Hongxun2)1)Department of Pathology,Zhengzhou Railway Vocational and Technical College,Zhengzhou 450052 2)Department of Histology and Embryology,Henan Medical College for Staff and Workers,Zhengzhou 450003;Effects of three types of macrophages culture supernatant on burst forming unite-erythroid and colony forming unite-erythroid in mice[J];Journal of Zhengzhou University(Medical Sciences);2009-05
9 QUAN Hong-xun,FU Li,ZHAO Feng-chen,et al.Henan Medical College for Staff and Workers,Zhengzhou 450003 China.;The Effects of Three Types of Macrophages Culture Supernatant on CFU-GM in Irradiated Mice[J];Chinese Journal of Radiological Health;2008-02
10 Huang Xiaogin Zhu BideDepartment of Anatomy, Sichuan Continuing EducationCollege of Medical Sciences, Chengdu 610041;An Experimental Study on L-cell HRF Induced by TSPG[J];Sichuan Journal of Auatomy;1998-04
【Secondary Citations】
Chinese Journal Full-text Database 5 Hits
1 Guo Ruiqing, Zhu Bide~* (The Second Affiliated Hospital of Qingdao Medical College, Qingdao, Chongqing University of Medical Science, Chongqing~* );THE EFFECT OF PERITONEAL MACROPHAGE CULTURE SUPERNATANTS ON MOUSE HEMOPOIESIS[J];Acta Anatomica Sinica;1992-03
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5 WANG Cheng-Long LI Wei-Min WANG Qi-Ru (Experimental Hemophysiology Laboratory, Hunan Medical University Changsha 410078);BIOLOGICAL CHARACTERISTICS OF L929 CELL LINE[J];Journal of Experimental Hematology;1995-04
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