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《Sichuan Medical Journal》 2009-09
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The comparison study of nicergolent and piracetam in treatment with vascular dementia.

XU Hong-hua.Affiliated Gulou Hospital of Nanjing University Medicine College,Nanjing,Jiangsu 210008,China  
Objective To compare and observe the clinical effects of nicergolent and piracetam in treatmem with vascular dementia(VD).Methods From January 2007 to January 2009,98 cases patients with VD were randomly classified into nicergnlent group with 49 cases and piracetam group with 49 cases.To compare the MMSE,WMS,CGI,ADL and clinical effect between the two groups.Results Compared with pre-treatment,the MMSE and WMS were significantly increased(P0.05),SI and ADL were significantly decreased(P0.05) after treatment in two groups.Moreover,the MMSE,WMS,SI and ADL in nicergolent group were significantly better than those in piracetam group(P0.05).The total effective rate(89.8%) in aleergnlent group were significantly higher than that(67.3%) in piracetam group(P0.05).There were no significant untoward reactions in both two groups.Conclusion Nicergolent was an effective drug in treatment with VD and more effective than piracetam.
【CateGory Index】: R743.3
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 Hai li bi nu er, WANG Yin hua, ZHAO Fa guo (Department of Neurology, The First Hospital of Peking University, BEIJING 100034, China);Randomized double-blind controlled study of oxiracetam vs piracetam in treatment of vascular dementia[J];Chinese Journal of New Drugs and Clinical Remedies;2003-11
【Co-citations】
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1 SHU Kai, XI Gui-fa, NIU Hong-quan, DONG Zhen, YU Jia-sheng, LEI Ting, LI Ling. Department of Neurosurgery, Tongji Hospital, Tongji Medical College, H uazhong University of Science and Technology, Wuhan 430030, China;Clinical evaluation of Oxiracetam in the treatment of craniocerebral trauma[J];Chinese Journal of Neuromedicine;2005-05
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4 WANG Shu-zhen~(1*) CHI Zhao-fu~1 MA Lin~1 ZHANG Yong~2 DI Qing~3 HAN Zhao~4 YU Hao~5 HAN Ting~6 (1.Department of Neurology,Qilu Hospital of Shandong University,Ji-nan SHANDONG 250012,China:2.Department of Neurology,Shandong Provincial Hospital,Ji-nan SHANDONG 250021,China;3.Department of Brain Hospital of Nanjing Medical University,Nanjing JIANGSU 210029,China;4.The First Affiliated Hospital of Wenzhou Medical College,Wenzhou ZHEJIANG 325000,China;5.Department of Epidemiology and Biostatistics School of Public Health,Nanjing Medical University,Nanjing JIANGSU 210029,China;6.Shijiazhuang Pharmaceutical Group Ouyi Pharmaceutical Company,Shijiazhuang HEBEI 050051,China);A randomized double-blind controlled multicenter study with oxiracetam for injection in treatment of organic brain syndrome[J];Chinese Journal of New Drugs and Clinical Remedies;2007-04
5 Zhang Yuhua~1 Li Yanli~2 Geng Jilu~2 1.Department of Pharmacy,81 Hospital of PLA,Nanjing 210002,China 2.Second Affiliated Hospital of General Hospital of PLA;Clinical Investigation of Efficacy and Safety of Nicergoline and Aniracetam in the Treatment of Vascular Dementia[J];Chinese Journal of Pharmacoepidemiology;2008-03
6 HUA Jin-bao (Zhejiang Province Anji the Third People's Hospital,313301,China);Clinical observation on oxiracetam's effects on rehsbitation of cognitive function in patients of hypertensive cerebral hemorrhage[J];Chinese Journal of Hospital Pharmacy;2008-14
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