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《Sichuan Medical Journal》 2011-10
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Curative effect of zine glycyrrhizate in treating the rotavirus infectious enteritis in chidren

ZHANG Li-xia1,LV Chun-yan2.1.The Second People's Hospital of Shuangliu,Shuangliu,Sichuan,610213;2.The Affiliated Hospital of Chengdu Tranditional Medicine University,Chengdu,Sichuan 610072,China  
Objective To study the curative effect of trace element zinc in treating the rotavirus infectious enteritis in children.Methods 125 children with rotavirus infectious enteritis who were treated from January 2009 to May 2010 were divided into treatment group(63 cases) and control group(62 cases).Balanced diet,microbial therapy,antiviral treatment,rehydration to maintain Water-Electrolyte,acid-base balance and other treatments were given to both two groups.Zine glycyrrhizate was given to children in treatment group only,0.75g/ each time,two times per day.Results The markedly effective rate was 44.4%(treatment group) and 24.2%(control group).The total effective rate was 92.1%(treatment group) and 66.1%(control group).Five cases in treatment group(7.93%) and 21 cases in control group(33.9%) were in effective.Significant difference between two groups indicates that curative effect in treatment group is better than that in control group.Conclusion Trace element zinc is a good assistant in treating the rotavirus infectious enteritis.
【CateGory Index】: R725.1
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【Citations】
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1 DENG Zhao-hui~2 XU Chun-di~1 CHEN Shun-nian~1 (1.Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine,Shanghai 200025,China; 2.Shanghai Children's Medical Center Affiliated to Shanghai Jiaotong University School of Medicine,Shanghai 200127,China);Establish rotavirus diarrhea model in neonatal mice and investigate the pathological pathogenesis[J];Journal of Clinical Pediatrics;2008-10
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