Analysis of Effect of Vinorelbine Combined with Cisplatin in Treatment of 39 Patients with Advanced Breast Cancer
QU Yuan-jiao,LIU Tao-wen,CAO Yi-lin,et al. (Nanxishan Hospital of Guangxi Zhuang Autonomous Region,Guilin 541002,China)
Objective: To evaluate the therapeutic effect and adverse effects of vinorelbine(NVB) and cisplatin on advanced breast cancer.Methods: 39 cases of pathologically confirmed advanced breast cancer were treated with combined chemotherapy including vinorelbine and cisplatin,NVB 25mg/m2 iv drip day 1 and day 8,cisplatin 30mg/m2 iv drip day 1 to day 3,a cycle was 21 to 28 days.Efficacy was evaluated after 3 cycles.Results: 4 cases obtained CR,16 had PR,13 had NC and 6 had PD.Main toxicity reactions were myelosuppression,gastrointestinal tract reaction.Conclusion: The combined chemotherapy containing NVB and DDP is effective and safe in the treatment of advanced breast cancer.
【CateGory Index】： R737.9