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《Journal of Shandong University of Technology(Natural Science Edition)》 2009-05
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Effects of compound nutrients on anti-oxidation and anti-fatigue in senile female mice

CHEN Yan-zhen(School of Life Science and Technology,Shandong University of Technology,Zibo 255049,China)  
To investigate the effects of compound nutrients on anti-oxidation and anti-fatigue in female mice,fifty Kunming female mice were randomly divided into control group,model group,low,medium,distilled water,high of compound nutrients groups,which were respectively given with distilled water and the compound nutrients at 0.09,0.18 and 0.36g/kg for 56 d.Aging mouse models were established by subcutaneous injection of 400 mg / kg of D-galactose at the nape,the control group received the same volume of saline.After 7 weeks,the loaded-swimming time was recorded and serum urea nitrogen was measured.After 8 weeks,liver glycogen,the contents of MDA,the activities of SOD in serum and liver were measured.Compared with the model group,loading swimming time,liver glycogen and the activities of SOD increased while the contents of MDA and serum urea nitrogen decreased in the experimental group dose-dependently.Compound nutrients can promote the abilities of anti-oxidation and anti-fatigue of senile female mice.
【Fund】: 山东省自然科学基金资助项目(2004ZX27)
【CateGory Index】: R151
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