Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Shandong Univenity(Health Scicnes)》 2005-10
Add to Favorite Get Latest Update

Inhibitory effect of chanfuning serum on the apoptosis of PC12 cells induced by 6-hydroxydopamine

MENG Hai-wei1, LIU Shu-wei1, XU Ji-ping2, FENG Lei1, HU Jian-li1, HOU Zhong-yu1, CHENG Bao-hua1(1.Department of Anatomy, School of Medicine, Shandong University, Jinan 250012, Shandong, China;2.Department of Neurology, Second Hospital of Shandong University, Jinan 250033, Shandong, China)  
Objective: To study the inhibitory effect of chanfuning serum on the apoptosis of PC12 cells induced by 6-hydroxydopamine (6-OHDA). Methods: Serum pharmacological method was used to make chanfuning serum. 6-OHDA and chanfuning serum were added into the medium of PC12 cells separately. MTT method was used to assay the cell's viability, and tyrosine hydroxylase (TH) and caspase-3 immunocytochemistry staining were used to evaluate the content of TH and count the number of apoptosis cells. Results: PC12 cell's viability and calibrated optic density of TH positive cells enhanced (P0.01), and the number of caspase-3 positive cells decreased(P0.01) significantly in chanfuning serum treated group compared with 6-OHDA treated group. Conclusion: Chanfuning serum may have direct nutritious effect, protect PC12 cells from injury induced by 6-OHDA, and produce anti-apoptosis effect to some extent.
【CateGory Index】: R285;
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 1 Hits
1 LI Yi-qun,SHEN Hui-feng(Department of Traditional Chinese Medicine,Renji Hospital affiliated to Medical College,Shanghai Jiaotong University,Shanghai 200127,China);Serum pharmacology test of external application of asthma plaster in guinea pigs[J];Pharmaceutical Care and Research;2008-04
Chinese Journal Full-text Database 7 Hits
1 WANG Xue Mei △, FU Hong, LIU Geng Xin (Institute of Integrated of Traditional Chinese and Western Medicine, Peking University, Beijing 100034,China);Effect of Herba Epimedii and Fructus Lycii on mitochondrial DNA deletion, activity of respiratory chain enzyme complexes and ATP synthesis in aged rats[J];Journal of Beijing Medical University;2002-01
2 Xu Jiping,et al(Research Group of Parkinson's Disease,Binzou.Medical college);CHAN FU NING PULVIS IN THE TREATMENT OF PARKINSON'S DISEASE[J];JOURNAL OF BINZHOU MEDICAL COLLEGE;1994-02
3 ZHOU Yi-can, CHEN Xiao-chun+ *, ZHU Yuan-gui, FANG fang, CHEN Li-min(Fujian Institute of Geriatrics, Union Hospital, Fujian Medical University, Fuzhou 350001, China);THE INFLUENCE OF GINSENOSIDE Rg1 ON JNK SIGNALINGCASCADE IN PD MOUSE SUBSTANTIA NIGRA NEURONS[J];Acta Anatomica Sinica;2003-05
4 Lan Zhang,Lin Li,Ya Li Li,Department of Pharmacology,Xuanwu Hospital,Capital University of Medical Sciences,Beijing Brain Aging Research Laboratory,Beijing 100053,China;Mechanism of the protection of stilbene glycoside which is the effective component of tuber fleeceflower root on nerve cells[J];Chinese Journal of Clinical Rehabilitation;2004-01
5 WANG Shao-Bin, LI Wei-Ping, HE Ting, WU Qiang, YIN Yan-Yan , MING Liang(Dept of Pharmacology, Anhui Medical University, HeFei230032);Protective effect of EA against cerebral ischemia-reperfusion injury[J];Chinese Pharmacological Bulletin;2004-03
6 RONG Juan 1 , CHEN Sheng di 1 ,LI Biao 2 , LIU Zhen guo 1 ( 1.Department of Neurology, 2. Department of Nuclear Medicine, Rui Jin Hospital, Shanghai Second Medical University, Shanghai 200025, China );6-Hydroxydopamine-induced apoptosis in PC12 cells and its probable molecular mechanism[J];Chinese Journal of Neuroscience;2001-04
7 TIAN Jiyu1, CHEN Jianzong1, CHEN Xiaoli2(1.Research Center of TCM,XiJing hospital,Fourth Military Medical University,Xi'an 710032;2.Dept.of Pharmacy,XiJing hospital,Fourth Military Medical University, Xi'an 710032);Protective effect of Prescription for Nourishing Liver- Kidney on Injured Cultured PC12 Cell in Vitro[J];Traditional Chinese Drug Research & Clinical Pharmacology;2004-01
Chinese Journal Full-text Database 10 Hits
1 LU Min1,SHEN Guo-ming2 (1.Tiantai Pingqiao Junior High school,Tiantai,Zhejiang 317203;2.College of Life Sciences,Zhejiang University,Hangzhou,Zhejiang,310058);Study on Diurnal Changes and Habitat-variability in Vegetative Organs of Carbohydrate Contents in Polygonum multiflorum Thuna[J];Northern Horticulture;2010-05
2 ZHANG Ying,CHEN Jianzong,HOU Rong-rong,et al(Institute of Traditional Chinese Medicine,Laboratory of Integrated Traditional Chinese Medicine andWestern Medicine on Elderly Encephalopathy,Xijing Hospital,Fourth Military Medical University,Xi'an,Shaanxi,710032);Neuroprotective effects of TSG on Degeneration of Nigral Dopaminergic Neurons Induced by Paraquat and Maneb in Mice[J];Journal of Chengdu University of Traditional Chinese Medicine;2008-01
3 MENG Ning,KONG Kai,LI Shi-weng(School of Chemical and Biological Engineering,Lanzhou Jiaotong University,Lanzhou 730070,China);Advances in Studies on Chemical Constituents and Pharmaceutical Activities in Species of Epimedium[J];Acta Botanica Boreali-Occidentalia Sinica;2010-05
4 SUN Xin1,GU Yi2,LI Xiao-Feng1,LI Xiao-Bing1,CHEN Jian-Zong1 1Laboratory of Integrated Traditional Chinese Medicine and Western Medicine in Elderly Encephalopathy,Research Center of Traditional Chinese Midicine,Xijing Hospital,2Pharmaceutical Preparation Section of Stomatology Hospital,Fourth Military Medical University,Xi'an 710033,China;Effect of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside against MPP~+ induced apoptosis in PC12 cells[J];Journal of the Fourth Military Medical University;2009-24
5 SHI Chong, ZHANG Yu-xin, ZHANG Zuo-feng Department of Anatomy, North China Coal Medical College, Tangshan 063000, China;Effect of phosphorylated-ERK1/2 on inducible nitric oxide synthase expression in the substantia nigra of mice with MPTP-induced Parkinson disease[J];Journal of Southern Medical University;2009-01
6 LI Yong-mei1 ,LI Xia2,3,ZHOU Zhao-li3(1.146 of Warehouse,State Food and Drug Administration,Shijiazhuang 050071,China;2.Department of Pharmacy,Ocean College of Shandong University at Weihai, Weihai 264209,Shandong Province,China;3.Department of Pharmacology,Shenyang Pharmaceutical University,Shenyang 110016,China);Proventive effects of Polygonum multiflorum Thunb.extract on nigrostriatal dopaminergic system lesion induced by paraquat in mice[J];The Chinese Journal of Clinical Pharmacology;2007-05
7 SUN Zhi-yong1,2,ZHAO Yan-ling2,WANG Jia-bo2,LI Rui-sheng3,WEI Si-si1,2,JIANG Feng-juan1,2,XIAO Xiao-he2 1.Chengdu University of Traditional Chinese Medicine,Chengdu 610075,China 2.Integrative Medicine Center of 302 Military Hospital,China Military Institute of Chinese Materia Medica,Beijing 100039,China 3.Animal Laboratory Center,302 Hospital of PLA,Beijing 100039,China;Study on Hot Property of Aconiti Lateralis Radix Praeparata and Its Compatibility with Zingiberis Rhizoma Based on Animal Temperature Tropism[J];中草药(英文版);2012-04
8 QIU Guang,WU Xiao-qiong,LUO Xue-gang~*(Department of Anatomy and Neurobiology,Xiangya School of Medicine,Central South University,Changsha 410013,China;Effect of polygonum multiflorum thunb on BDNF expression in rat hippocampus induced by amyloid beta-protein(Aβ) 1-40[J];Journal of Central South University(Medical Sciences);2006-02
9 ZHA Sheng-hua,ZHANG Hong(Beijing Tongrentang Health Pharmaceutical Co.,Ltd.,Beijing 100085,China);Study on Preparation of 2,3,5,4"-Stilbene Glucosid from Polygoni Multiflori Radix[J];Research and Practice on Chinese Medicines;2011-06
10 ZHU Liming Department of Integrated Traditional and Westen Medicine, Luoyang City Locomotive Hospital of Henan Province ,Henan (471002);Clinical Observation on Effect of Naomaitai Capsule Combined with Yishenjiannao Decoction in Treating Alzheimer's Disease[J];Nei Mongol Journal of Traditional Chinese Medicine;2011-14
Chinese Journal Full-text Database 10 Hits
1 Zhan Hongsheng Zhejiang College of TCM,Hangzhou(310009);Experimental Method of Medicinal Serum and Its Application Prospects in the Study and Making of New Chinese Drugs[J];JOURNAL OF ZHEJIANG COLLEGE OF TCM;2000-02
2 LI Jun-yan,YANG Ming-hui,ZHAO Guan-ying(Institute of TCM,PLA General Hospital,Beijing 100853,China);Discussion on the fundamental pathogenesis of Parkinson’s disease (PD):kidney deficiency and blood stasis[J];China Journal of Traditional Chinese Medicine and Pharmacy;2008-09
3 PU Xiao Ping 1, LI Xiao Rong 1, LI Hui Nong 1, TU Peng Fei 2, SONG Zhi Hong 2, LI Chang Ling 1 (1. Department of Molecular and Cellular Pharmacology, 2. Department of Natural Medicines, Peking University School of Pharmaceutical Sciences, B;Campneoside Ⅱ of Cistanche tubulosa (Schenk) R. Wight protects neurons from apoptosis induced by neurotoxin 1 methyl 4 phenylpyridinium (MPP +)[J];Journal of Beijing Medical University;2001-03
4 HE Qihua, ZHOU Huifang, XUE Bing, NIU Dongbin, WANG Xiaomin △ (Neuroscience Research Institute, Peking University, Beijing 100083,China);Neuroprotective effects of Tripterygium Wilforddi Hook F monomer T_(10) on glutamate induced PC12 cell line damage and its mechanism[J];Journal of Beijing Medical University;2003-03
5 LI Hai-long,SHU Yan,HOU Rong-Rong,et al(Xijing Hospital,The No.4 Army Medical University,Xian 710032,China);Neuroprotective Effects of Gastrodin on PQ and MB Induced Dopaminergic Neurons Damage in C_(57) BL mice[J];Journal of Chengdu University of Traditional Chinese Medicine;2010-01
6 LU Qi,HUANG Jian-jun,ZHANG Lan-hui,et al. The first Affiliated Hospital of Anhui TCM,Hefei,Anhui 230031,China;Study of proton magnetic resonance spectroscopy on early diagnosis in idiopathic parkinson's disease[J];Chinese Journal of CT and MRI;2009-05
7 WANG Ming-wei * 1,GU Ping 1,LIU Li 2,WANG Yan-yong 1,CUI Dong-sheng 2 (1.Department of Neurology, No.1 Hospital, Hebei Medical University, Shijiazhuang 050031,China; 2.Central Laboratory,No.1 Hospital);Protective effect of Ginkgo biloba L. extract on PC12 cell damage induced by rotenone and MPP~+ in vitro[J];Academic Journal of Second Military Medical University;2005-02
8 TIAN Ji Yu 1, CHEN Jian Zong 1, CHEN Xiao Li 2, YANG Hao 3 1Department of Traditional Chinese Medicine, 2Department of Pharmacy, Xijing Hospital, 3PLA Institute of Neurobiology, Fourth Military Medical University, Xian 710033, China;Effects of Cistanche on apoptosis of PC12 cells[J];Journal of The Fourth Military Medical University;2004-10
9 XIANG Yang, CHEN Nan-Nan, ZHANG De-Jie,HUANG Shi-Lin,LI Yue-Meng Department of TCM & Hematology, 210th Hospital of Chinese PLA, Dalian 116021, China;Establishment of serum pharmacology testing method for Compound Realgar Natural Indigo Tablets[J];Journal of The Fourth Military Medical University;2005-17
10 XI Shu-Fang~1, CHEN Jian-Zong~1, WANG Bai-Ren~2, YANG Hao~2, GAO Jian-Yuan~3, TIAN Ji-Yu~1, KANG Xiao-Gang~1~1Research Center of Traditional Chinese Medicine, Laboratory of Integrated Traditional Chinese Medicine and Western Medicine for Encephalopathy in Elderly, Xijing Hospital, Fourth Military Medical University, Xi'an 710033, China, ~2PLA Institute of Neurobiology, ~3Department of Geriatrics, Xijing Hospital, Fourth Military Medical University, Xi'an 710033, China;Protective effect of EGB761 on embryonic rat mesencephalic dopaminergic neurons in vitro from MPP~+-induced injury[J];Journal of the Fourth Military Medical University;2006-01
【Secondary References】
Chinese Journal Full-text Database 6 Hits
1 WEN Xiao-dong;REN Ding;WANG Chun-ling;KONG De-yan;WANG Kai-hua;Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine;Guangxi University of Chinese Medicine;;Effects of Chinese herbal medicine Pabing Ⅱ Formula on quality of life of patients with Parkinson's disease at early-stage[J];China Journal of Traditional Chinese Medicine and Pharmacy;2013-10
2 ZHAO Ying,LIU Qing-shan,XU Si-fan(Minzu University of China,Chinese Minority Traditional Medical Center,Beijing 100081,China);The Application of Serum Pharmacology in Reproductive System[J];Lishizhen Medicine and Materia Medica Research;2011-04
3 YE Shuifen;CAI Jing;College of Integrative Medicine,Fujian University of Traditional Chinese Medicine;;A Review of JAK/STAT Signal Transduction Pathway and Chinese Medicine in The Treatment of Parkinson's Disease[J];Journal of Practical Traditional Chinese Internal Medicine;2013-13
4 YUAN Hui-li~1,2,WANG Xuan~1,ZHANG Li-juan~1,LIANG Zhi-gang~1,WANG Xiao-min~1 (1.Key Laboratory of Neurodegenerative Diseases of the Ministry of Education,Capital Medical University,Beijing 100069,China;2.Beijing Health School,Beijing 100053,China);Mechanism and research progress of Chinese traditional medicine in the prevention and treatment of parkinsons disease[J];Chinese Pharmacological Bulletin;2010-07
5 ;A research overview of the mechanism of acupoint application in treating bronchial asthma[J];Clinical Journal of Chinese Medicine;2012-24
6 Lv Xiliang(Workers' Hospital of Henan Province,Zhengzhou 450002,China);Chinese Medicine Treatment of Parkinson's Disease and Pharmacological Activities of Medication[J];Asia-Pacific Traditional Medicine;2013-07
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Feng Wei,Shi Yinyu,Shen Peizhi,etal Orthopedics Instituteof Shanghai University of TCM (2 0 0 0 3 2 );ln Vitro Study of Sera Contained in Bushenfang and Rouganfang (China herbs) on Proliferation Dynamics of Chondrocytes[J];Journal of Zhejiang College of Tcm;2001-04
2 PU Xiao Ping 1, LI Xiao Rong 1, LI Hui Nong 1, TU Peng Fei 2, SONG Zhi Hong 2, LI Chang Ling 1 (1. Department of Molecular and Cellular Pharmacology, 2. Department of Natural Medicines, Peking University School of Pharmaceutical Sciences, B;Campneoside Ⅱ of Cistanche tubulosa (Schenk) R. Wight protects neurons from apoptosis induced by neurotoxin 1 methyl 4 phenylpyridinium (MPP +)[J];Journal of Beijing Medical University;2001-03
3 Jin Daozhong,Liu Zhengqing,Ma Zhijian,Zhang Zhijun,Cai Weijun,Weng Xiaodan. Department of Anatomy,Xiangya Medical College,Central South University,Changsha 410078 China;Effect of cerebral ischemia on Willis cycle in the Kunming mouse[J];Anatomy Research;2002-03
4 CHEN Ying, CHEN Xiao\|chun\+ * (Fujian Institute of Geriatrics, Union Hospital, Fujian Medical Univirsity, Fuzhou\ 350001,China);Bcl-2 FAMILY:THE IMPORTANT REGULATING PROTEINS DURING GINSENOSIDE RG1 PROTECTION AGAINST APOPTOSIS OF NIGRA NEURONS[J];Acta Anatomica Sinica;2002-05
5 Lu Yunru , Deng Qiaohong , Che Qiufang , et al. (College of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029);Quantitative Determination of 2,3,5,4' Tetrahydroxy stilbene-2-O-β-D glucoside in Polygonum Multiflorum and Its Preparation[J];JOURNAL OF BEIJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE;1998-06
6 CHENG Xi qun,CAI Ding gang,ZHENG ZhenHua Shan Hospital,School of Medicine, Fudan University Institute of Chinese and Western Medicine Integration,School of Medicine,Fudan University;Influence of Liver-Nourishing and Wind-Extinguishing Formulas and Drugs on Rotating Behavior in Parkinson Rats[J];Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai;2001-02
7 MIAO Jian Ting, LI Zhu Yi , LIN Hong,et al.Center of Neurology, Tangdu Hospital,Fourth Military Medical University,Xi'an 710038,China;Ultrastructural changes of focal neurons after amyloid-beta protein injected into meynert nucleus in rat[J];Modern Rehabilitation;2002-03
8 TANG Hui dong, CHEN Xue hua, CHEN Sheng di.Rui jin Hospital, Shanghai Second Medical University, Shanghai 200025,China;Effects of nerve growth factor on Aβ_(25. 35) induced hippocampal neuron injury[J];Modern Rehabilitation;2002-13
9 Heng-Bing Zu,Department of Neurology,Jinshan Ho spital,Fudan Univer-sity,Shanghai 200540,China Sheng-Di Chen 1 ,Liang Liang 2 ,Jie-Yi Xu 2 ,1 Department of Neurology,2 Laboratory of Clinical Neurology,R uijing Hospital,Shanghai Second Me di-cal University,Shanghai 200540,China;Significance of IL-1αand S100βexpression induced by Amyloid-βprotein 40 in the pathogenesis of Alz heimer's disease[J];Chinese Journal of Clinical Rehabilitation;2003-28
10 XU Du Juan, WU Qiang, YANG Yan, CHEN Ming Zhu (Institute of Clinical Pharmacology,Anhui Medical University,Hefei 230032);Antitumor activity of AST and its mechanism of action[J];Chinese Pharmacological Bulletin;2003-07
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved