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《Journal of Shandong University(Health Sciences)》 2008-08
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CT perfusion imaging and determination of Glu and GABA content in acute cerebral infarction

MAN Xiao,LENG Zhen-pu,PANG Zai-ying,DU Yi-feng (Department of Neurology,Provincial Hospital Affiliated to Shandong University,Jinan 250021,China)  
Objective To investigate the application of computed tomography perfusion imaging(CTPI)combined with determination of Glu and GABA in the plasma in diagnosis of acute cerebral infarction(CI).Methods 57 patients with acute cerebral infarction onset within 24 hours were examined by conventional CT and CTPI.CTPI yielded a set of relative cerebral blood flow(rCBF),mean transmit time(MTT) and time to peak(TP).By mean of high-performance liquid chromatography,the levels of Glu and GABA in the plasma of all patients were determined.Results Conventional CT scan showed a low-density signal in 26 of 57 patients.CTPI revealed normal perfusion in 3 patients and hypo-perfusion in 54 patients.The regional cerebral blood flow(rCBF),time to peak(TP),and mean transit time(MTT)were obviously changed in 54 patients by CTPI.The ischemic lesion side as compared with the opposite side,and the core of the ischemic lesion as compared with the peripheral zone were significantly changed(P0.05).A linear correlation analysis showed that there were positive correlations between infarction volume and plasma levels of Glu and GABA(r=0.88,P0.01;r=0.47,P0.01) and the infarction volume.Conclusion CTPI combined with determination of Glu and GABA in plasma can be used in diagnosis of early stage of cerebral infarction and measurement of infarct volume,so it is great for prognosis and treatment.
【CateGory Index】: R743.3
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Chinese Journal Full-text Database 2 Hits
1 SHEN Xia,HAN Xian-jun,CUI Gui-yun,et al.Department of Neurology, Affiliated Hospital of Xuzhou Medical College, Xuzhou 221002, China;Clinical applied value of computed tomography perfusion imaging in early stage of ischemic stroke[J];Journal of Clinical Neurology;2007-03
2 ZHANG Yong-hai,BAI Jun-hu,ZHANG Ming,YANG Guo-cai,TANG Gui-bo,FANG Jun,SHI Wei,LI Xing-hua,LIU Su-ping,LU Qing,TANG Jun. Department of Radiology, Qinghai Provincial People′s Hospital,Xining 810007,China;A study of whole brain perfusion CT and CT angiography in hyperacute and acute cerebral infarction[J];Chinese Journal of Radiology;2005-07
Chinese Journal Full-text Database 6 Hits
1 ZHOU Zhipeng,DENG Yanxian, QIU Weijia,et al.Department of Radiology,Affiliated Hospital of Guilin Medical College 541001,P.R.China;The DSA and CT Perfusion Evaluation of New Model of Artery Occlusion in Monkey[J];Journal of Clinical Radiology;2008-11
2 LIU Xiao-dong,YAO Xiao-ping,XIE Wen-xia,et al.Department of Radiology,Workers General Hospital of Tongling Nonferrous Metals Group,Tongling 244000,Anhui,China;Comparative Study on Quantitative CT Values of Fresh and Olden Lacunar Cerebral Infarction[J];Chinese Journal of General Practice;2010-02
3 ;Clinical and imagic analysis of acute cerebral vascular disease with onset of seizure[J];Journal of Medical Imaging;2005-11
4 YAO Zhen-wei ZHANG Fang FENG Xiao-yuan Department of Radiology.Huashan Hospitar,Fudan University;Evaluation of Rabbit Cerebral Mini-embolic Ischemia Model with CT Perfusion[J];Chinese Computed Medical Imaging;2008-04
5 YU Qin,RAN Long-fu;CT diagnosis advancement of acute cerebral infarction[J];Practical Journal of Clinical Medicine;2009-01
6 JIANG Bao-dong* FENG Xiao-yuan LIU Cheng LI Ke YU Fu-hua *Department of Radiology,Huashan Hospital,Fudan University,Shanghai 200040,China;Study on imaging parameters of multi-slice spiral CT long coverage angiography in intracranial and cervical arteries[J];Chinese Journal of Radiology;2006-09
Chinese Journal Full-text Database 10 Hits
1 Wang Aicheng Wangyulai Libai et al(Dongfang Hospital, Beijing University of TCM; General hospital of PLA);Positron Emission Tomography (PET) on Related Encephalic Regions of Syndrome of Stagnation of Liver Qi[J];China Journal of Traditional Chinese Medicine and Pharmacy;2005-08
2 Zhong Xiaolan~1 Lv Zhiping~1 Qian Lingjia~2 Liu Xiaohua~2 Tan Qinxiang~1 Zhang Xiaogang~1(()~1Southern Medical University,Guangzhou 510515;()~2 Institute of Hygiene Environmental Medicine,Tianjin 300050);Differential Expression of Serum Proteome on Stagnation on Liver-QI Syndrome Model Rats[J];China Journal of Traditional Chinese Medicine and Pharmacy;2006-07
3 WANG Tong-sheng,XIE Ming,ZHANG Yan-xia,YAN Yue(Beijing University of Chinese Medicine,Beijing 100029,China);Changes of ethology and monamine transmitter in stagnation of liver qi model rats and intervention of bupleurum root[J];China Journal of Traditional Chinese Medicine and Pharmacy;2008-10
4 LIU Ji hong reviewing, CAO Wei xin checking (Department of Clinical Nutrition, Ruijin Hospital of Shanghai Second Medical University, Shanghai 200025, China);Effects of n-3 fatty acids on prevention and therapy of tumor[J];Parenteral & Enteral Nutrition;2004-01
5 CHEN Jian-wei 1,LI Xiang 1,CHEN Jin 2,ZHAO Wu-sheng 2 (1.Nanjing University of Traditional Chinese Medicine,Nanjing 210029,China; 2.Institute of Criminal Science & Technology in Jiangsu,Nanjing 210024,China);Comparative Analysis of Inorganic Elements of Fingernail of Homo sapiens L.in the Normal Healthy Adult and the Patients with Liver-qi Depression[J];Trace Elements Science;2001-11
6 HOU Anji1,HU Yan1,ZHOU Wei1,ZHANG Hongwei1,TANG Zhijiao2 1 Dept.of Oncology,the 7th Peoples' Hospital Shanghai,Shanghai 200137,China 2 Dept.of Medical Experiments,School of Medicine,Wuhan University,Wuhan 430071,China;Expression of c-fos and Caspase-3 Protein in Geriatric Rats Hippocampus CA3 Area Induced by Chronic Unpredictable Mild Stress[J];Medical Journal of Wuhan University;2008-01
7 WANG Zhe~ 1,* ,HU Sui-yu~ 2 ,LEI De-liang~ 3 , SONG Wei-xi~ 2 (1.Department of Combined Traditional Chinese Medicine, Second Xiangya Hospital, Central South University, Changsha 410011; 2.Institute of Combined Traditional Chinese and Western Medicine, Xiangya Hospital, Central South University, Changsha 410008; 3.Department of Anatomy and Neurobiology, Xiangya School of Medicine, Central South University, Changsha 410078, China);Effect of chronic stress on PKA and P-CREB expression in hippocampus of rats and the antagonism of antidepressors[J];Journal of Central South University(Medical Sciences);2006-05
8 Chen Song,Li Jiabang,Zhu Shuangluo,et al (Institute of Combined Traditional Chinese and West Medicine,Xiangya Hospital,Central South University,ChangSha 410008);The experiment Observation of Alteration of Activity of T-and B-Lymphocytes And Influence of Dispersing Stagnated Hepato-qi Treatment[J];Journal of Hunan College of Traditional Chinese Medicine;2001-02
9 Chen Zeqi,Li Xuewen,Chen Guolin,et al(Department of TCM of Xiangya Hospital, Hunan Medical University,Changsha 410008);ANALYSIS OF SERUM CONTENT OF GASTRIN IN PATIENTS WITH SYNDROME OF LIVER-QI STAGNATION[J];JOURNAL OF HUNAN COLLEGE OF TRADITIONAL CHINESE MEDICINE;1998-01
10 Tang Yiting Chen Jiaxu(Beijing University of Traditional Chinese Medicine, Beijing 100029);Regulative Effects of Three TCM Formulas on Hypothalamus-Pituitary-Adrenal Axis in the Rats with Chronic Restrained Stress[J];Journal of Beijing University of Traditional Chinese Medicine;2002-03
【Secondary Citations】
Chinese Journal Full-text Database 5 Hits
1 Man Xiao, Leng Zhenpu, Pang Zaiying, et al. Department of Neurology, Shandong Provincial Hospital, Jinan 250021,China;The value of combined application of CT perfusion imaging and CT angiography in the diagnosis of hyperacute ischemic cerebrovascular disease[J];Journal of Clinical Neurology;2004-02
2 Chen Xingrong; Shen Tianzhen (Department of Radiology, Huashan Hospital, Shanghai Medical University, Shanghai 200040);Imaging of Cerebral Infarct[J];CHINESE JOURNAL OF MEDICAL COMPUTED IMAGING;2000-01
3 LU Jie, LI Kuncheng, DU Xiangying Department of Radiology, Xuanwu Hospital, the Capital Medical University, Beijing 100053, China;The preliminary study of CT cerebral perfusion imaging in transient ischemic attacks[J];Chinese Journal of Radiology;2002-04
4 GUAN Xiaoting *,LIU Xiang, LONG Jie, et al. *Department of Neurology,Beijing Tiantan Hospital,Beijing 100050,China;CT perfusion imaging and CT subtraction angiography in diagnosing acute ischemic cerebrovascular disease[J];Chinese Journal of Neurology;2000-05
5 CHEN Wei wei, QI Jian pin *, XIAO Ming, SONG Jin mei (Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China);Consistency between two methods for penumbra assessment by CT perfusion in hyperacute cerebral ischemia[J];Chinese Journal of Medical Imaging Technology;2005-02
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