Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Pharmaceutical Research》 2013-03
Add to Favorite Get Latest Update

Research on hypolipidemic effect of synbiotics in Hyperlipidemia rats

CHENG Xiu-fang,LIU Hong,WANG Cong-cong,LI Dan,XIE Li-min,GU Wei(Shandong Boly-lely Biongineering Co.,Ltd.,Taian 271000,China)  
Objective To investigate the hypolipidemic effect of synbiotics composed of two strains of probiotics(Streptococcus thermophilus,Lactobacillus plantarum)and two kinds of prebiotics in Hyperlipidemia rats.Methods Build lipid metabolism disorder model using Wistar rats,set up three dose groups respectively 2.25,0.45,0.09 g·kg-1,a model group and a normal group,Gavage 30 days,Detect the level of total cholesterol(TC),triglyceride(TG)and high-density lipoprotein cholesterol(HDL-C)of rat serum using Biochemical kit,and detect the liver spleen and kidney index.Results Synbiotics had no effects on feed intake and liver spleen kidney index.Three synbiotics dose groups(treatment group)could significantly reduce the levels of total cholesterol(TC)and triglyceride(TG)compared with the control group.TC and TG of rats in the model group compared with normal groups were significantly increased(P0.01),showed that the model was established,three synbiotics dose group(treatment group)of TC and TG than that in the model group significantly decreased(P0.01).Conclusion Synbiotics had good function of reducing blood lipid.
【CateGory Index】: R96
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 5 Hits
1 ZHANG Hao, HUA Wei, GUO Ben-heng, JIANG Neng-qun, BU Yong-shi (School of Food Science and Technology, Southern Yangtze University,Wuxi 214036; Shanghai Bright Dairy R&D Center,Shanghai 200072; Shanghai Fisheries University, Shanghai200090);Bile tolerance, bile salt-deconjugation and cholesterol-assimilating ability of lactobacillus plantarum strains[J];Industrial Microbiology;2003-02
2 JI Xu,HOU Hong-man,WANG Xiu-ling,SUN Si(College of Bio & Food Technology,Dalian Polytechnic University,Dalian 116034,China);Mechanism on L.casei ZP-W cholesterol-lowering in vitro[J];China Dairy Industry;2010-04
3 Xiao Linlin et al;Cholesterol-degrading Activity of Lactobacillus casei Isolated from Tibet Koumiss[J];Food Science;2003-10
4 WANG Yi-Ming1 FAN Xiao-Bing2 HANG Xiao-Min2 LI Kun-Bao1 YANG Hong 1** (College of Life Science and Biotechnology,Shanghai Jiao Tong University,Shanghai 200240) 1 (Shanghai Jiao Da Onlly Co.,Ltd,Shanghai 200030) 2;in vitro Selection of Probiltic Lactobacillus from the Human Feces and Their Mechanism on Cholesterol-lowering[J];Microbiology;2006-06
5 Ping Yu,Haisen Sun,Jianrong Li,Xiaohui Wang,Haixia Lu College of Food Science and Biotechnology,Zhejiang Gongshang University,Hangzhou 310035,China;Cholesterol-degrading by Lactobacillus plantarum LpT1 and LpT2 in vitro[J];Acta Microbiologica Sinica;2011-04
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 TIAN Hong-lei et al(School of Food Science,Shihezi University,Shihezi,Xinjiang 832000);Study on the Intervention of Lactobacillus TZ-5 on Blood Lipid Level of Rats with High-fat Diet[J];Journal of Anhui Agricultural Sciences;2012-12
2 JIAO Yuehua1,2,ZHANG Lanwei1,YI Huaxi1,ZHANG Lili1,MA Wei3(1.College of Food Science and Engineering,Harbin Institute of Technology,Harbin 150090,China;2.Center of Drug Safety Evaluation,Heilongjiang University of Chinese Medicine,Harbin 150040,China;3.Heilongjiang Entry-exit Inspection and Quarantine Bureau,Harbin 150001,China);Cholesterol removing ability and bile tolerance of lactic acid bacteria isolated from fermented yak milk[J];Journal of Northeast Agricultural University;2012-02
3 FAN Li-ping et al(Department of Biotechnology,Hangzhou Wanxiang Polytechnic,Hangzhou,Zhejiang 310023);Isolation,Identification and Characteristics of Lactobacillus plantarum Strains[J];Journal of Anhui Agricultural Sciences;2012-35
4 BO Xin,LI Jing-xia,YE Lei(Teachers' college,Beijing Union University,Beijing 100011,China);Experiments on Anti-aging Effect of the Tibetan Kefir Yoghourt[J];Journal of Beijing Union University;2013-03
5 LI Xiu-juan1,SHEN Jun-zi2,LIU Ning2,YANG Liu2(1.Physical Education Department,Hefei University of Technology,Hefei 230009,China;2.School of Biotechnology and Food Engineering,Hefei University of Technology,Hefei 230009,China);Effect of probiotics on TC and TG in experimental hyperlipidemic mice[J];Journal of Hefei University of Technology(Natural Science);2008-12
6 Zhu Jihong Collage of Life-science,Heilongjiang University(150080);Application And Prospect of Lactobacillus in Medicine Field[J];Heilongjiang Medicine Journal;2007-01
7 LI Li1),ZHANG Xinping2),WANG Qiushui3),ZHANG Yan1),WANG Haiyu1),CHEN Dongfang1) 1) Henan Center for Disease Control and Prevention,Zhengzhou 450016 2) Department of Clinical Medicine,Medical School,Hebi Vocation and Technology College,Hebi 458000 3) Central Blood Bank of Leshan,Leshan 614000;Effects of compound capsule containing bifidobacterium and lactobacillus acidophilus on immunity function of mice[J];Journal of Zhengzhou University(Medical Sciences);2010-04
8 ZHOU Jian-zhong1,HUANG Kai-hong1,DONG Ming-sheng2,JIANG Han-hu2(1.Institute Agro-product Processing,Jiangsu Academy of Agricultural Sciences,Nanjing 210014,China;2.College of Food Science and Technology,Nanjing Agricultural University,Nanjing 210095,China);Comparison of Microbial Community Structures of Kefir and Tibetan Kefir Grain[J];Jiangsu Journal of Agricultural Sciences;2008-05
9 JU Hua,LIU Shu-liang,AO Ling,WANG Yi(Department of Food Science,Sichuan Agricultural University,Ya'an 625014,China);Study on characteristics of growth,screening and identification of cholesterol-reducing Lactic acid bacteria[J];China Dairy Industry;2007-08
10 JI Xu,HOU Hong-man,WANG Xiu-ling,SUN Si(College of Bio & Food Technology,Dalian Polytechnic University,Dalian 116034,China);Mechanism on L.casei ZP-W cholesterol-lowering in vitro[J];China Dairy Industry;2010-04
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 GONG Zheng1;XUE Ping-hai1;YAN Shi-fa2;CAO Wen-wei (1. School of Biological science,Liaoning Normal University,Dalian,116029;2.Dept.of Biological and Chemical Science,Benxi College of Metallurgy,Benxi,Liaoning,117022,China);On Research Situation on Bacteriocins Produced from Lactic Acid Bacteria[J];Journal of Benxi College of Metallurgy;2004-02
2 MEI Lin,MA Li-li,XUAN Kang-kang(Anhui Agricultural University,Hefei 230036,China);Cholesterol-reducing Lactic Acid Bacteria Screening and Research[J];Packaging and Food Machinery;2009-05
3 CHEN Jun, CHANG Shan, ZHANG Ya ping,XIAO Guang xia (Institute of Burn Research,Southwest Hospital,Third Military Medical University, Chongqing 400038,China);Study on factors involved in adherence of bifidobacteria to intestinal epithelial cells in rats[J];Acta Academiae Medicine Militaris Tertiae;2002-02
4 JIN Yu-fang,ZHANG Li-shi(Shichuan Province Institute of Natural Medicine,Chengdu 610000 China);Pharmacodynamic and Toxicological Effects of Lideiyipian[J];Trace Elements Science;2001-09
5 WANG Li ying(The Ist people hospital of Changzhou, Jiangsu, Changzhou 213003);Study on Hepatic Protection and Decrease of Enzyme of Erzhi Pill[J];Strait Pharmaceutical Journal;2002-01
6 HANG Feng1, GUO Benheng1, REN Lu1, GONG Guangyu1, WANG Yinyu1, CHEN Wei2, ZHANG Hao2(1Technical Center, Bright Dairy & Food Co.Ltd., Shanghai 200072,China; 2State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, Jiangsu,China);Application of mixture design to optimizing compound emulsifiers for ultra-high temperature cow milk[J];Journal of the Chemical Industry and Engineering Society of China;2009-04
7 ZHENG Jian(Dept. of biol. , Huanggang Normal University, Huangzhou 438000,Hubei);Lactic acid bacteria's influence on blood lipids[J];Journal of Huanggang Normal Universirt;2002-03
8 SHI Ru-ling 1,2 ,ZHAO Chao-xian 1 ,ZHU Hai-bao 1 ,YANG Yuan 1 ,WANG Su-ling 1 ,JIANG Ling-ling 1* (1.Department of Biochemistry,Hebei Medical University,Shijiazhuang 050017; 2.Department of Biochemistry,Xinxiang Medical College,Xinxiang 453003,China);Increase of bile acid biosynthesis enhances the expression and activity of D-bifunctional protein in rat liver[J];Basic & Clinical Medicine;2006-07
9 CHEN Kai ,ZHANG Yan Fang,WANG Qian,SHAN Li Mei,JIANG Yu Ge,MU Shao Feng,LIU Shu Hong,WANG Hai (Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences,Beijing 100850);Characteristics of Hypercholesterolemia and Atherosclerosis in Rabbits Quails and Rats Fed with High Cholesterol Diet[J];Pharmaceutical Journal of Chinese People's Liberation Army;2001-03
10 Guo Songnian 1, Tian Shumei 2, Bai Hongtao 3 1. Northwest Sci Tech University of Agriculture and Forestry (Yangling 712100) 2. Xi'an Oils & Fats Research & Design Institute, State Adminstration of Grain Reserve (Xi'an 710082) 3. Dalian Dacheng Lianghong Food Co. Ltd. (Dalian 116633);Lactic acid bacteria and their fermenting food[J];Cereal and Food Indastry;2005-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved