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《上海大学学报(英文版)》 2008-01
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Evaluating effects of gypenosides and soyasaponins on differentiation of neural stem cells as an in vitro model

WU Jie WEN Tie-qiao Laboratory of Neural Molecular Biology,School of Life Sciences,Shanghai University,Shanghai 200444,P.R.China  
Neural stem cell has a potential to differentiate into neurons,astrocytes and oligodendrocytes.It provides an in vitro model to screen herbal medicines on the cellular differentiation and development level.In this work,active component from gypenosides and soyasaponins was prepared to investigate their effects on the differentiation of neural stem cells..Both gypenosides and soyasaponins promote the differentiation of neural stem cells.This method provides speed and practicality for screening effective herbal medicine.It is well suited for studying the mechanism of cell differentiation and development.
【Fund】: the National Basic Research Program of China(Grant No.2006CB500702);; the National Natural Science Foundation of China(Grant No.30570590);; the Science Foundation of Shanghai Municipal Commission of Science;; Technology(Grant No.03JC14030)
【CateGory Index】: R285.5
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