Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Acta Universitatis Medicinalis Secondae Shanghai》 1991-03
Add to Favorite Get Latest Update

The Inhibitory Effects of Salvia Miltiorrhiza and Aristolochia on Matrix Production in Fibroblasts

Zeng Minde, et al Shanghai Instite of Digestive Disease, Shanghai Second Medical University, Shanghai  
The ~3H-hydroxyproline, P-Ⅲ-P and fibronectins produced by fibroblasts in 10% FCS BME with Salvia miltiorrhiza, Aristolochia, colchicine or dexamethasone were determined. The contents of ~3H-hydroxyproline incorporating into the fibroblasts cultured with different drug were 1/3-1/2 of that in the culture without drug(P0.05). The collagen synthesis rates of cultures with drugs were 3.6-9.5%, while that of the control culture was 13.7%. The fibronectines produced by fibrobiasts cultured with Salvia miltiorrhiza, Aristolochia or colchicine were half in amount as that produced by the control (P0.005). The amounts of P-Ⅲ-P in the cultures with Salvia miltiorrhiza or colchicine were decreased to one third of the control (P0.01). This study indicates that Salvia miltiorrhiza and Aristolochia can considerably inhibit both fibroblasts and their synthesizing activity of matrix.
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 6 Hits
1 Chen Xiaonan, Zhu Xi, Fang Zhiming Medical School of Hangzhou Teachers College, Hangzhou(310012);The Effect of Radix Salvia Mitorrhiac Injection on the Blood Serum TNF of Alcoholic Liver Injury Rat[J];Journal of Zhejiang College of Tcm;2004-03
2 FANG Zhi-ming,CHEN Xiao-nan(Department of Basical Medical Science,Hangzhou Teachers College,Hangzhou,Zhejiang 310036,China);The effect of radix salvia mitorrhiac injection agent on IL-6 of serum in rats with alcoholic liver injury[J];Journal of Hangzhou Teachers College(Medical Edition);2006-02
3 Li Peng,Jiang Hongbing,Gong Yaping. College of Stomatology West China University of Medical Science 610041;The inhibitory effects of Danshen on adhesion and proliferation of Bcacd885 and Tca8113[J];JOURNAL OF MODERN STOMATOLOGY;1999-02
4 LIANG Li, LUO Shao-jun, TANG Shao-ming,et al (Institute of Plastic Surgery in Guangdong Medical College, Zhanjiang 524001,China);Effects of aristolochic acid on hypertrophic scars in the rabbit ears[J];Practical Journal of Clinical Medicne;2005-01
5 Liu Min, Peng Mingxing, Liu Ming et al. Department of Pediatric Surgery, First University Hospital, West China University of Medical Sciences, Chengdu, P.R.China 610041;THE EXPERIMENTAL STUDY OF THE EFFECT OF INSULIN AND DANSHEN ON CULTURE OF FIBROBLAST IN VITRO[J];CHINESE JOURNAL OF REPARATIVE AND RECONSTRUCTIVE SURGERY;1998-01
6 YU Li-ping,CHEN Xiao-nan,FANG Zhi-ming (Medical school of Hangzhou Teachers College,Hangzhou 310012,China);Effect of Radix Salvia Mitorrhiac Injection on the blood serum ALT and AST of Alcoholic Liver Injury Rat[J];China Journal of Basic Medicine In Traditional Chinese Medicine;2004-07
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Zhong Jinyi, Li Shiru, Sun Fengyun, et al Medical College of Qingdao University, Qingdao\ 266021;THE COOPERATIVE INHIBITION EFFECT OF GRAPE PROCYANIDIN AND RIDIOTHERAPY ON SARCOCARCINOMA S180 OF MICE[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;1999-05
2 BAO Fang ying 1,WANG Jun 2 (1.Anhui Agr Technical Tearchers College,Anhui Fengyang 233100; 2.Wuhu District Hygiene School,Anhui Wuhu 241000);Relationship Between Sex Hormone Change and Sex Gland Growth in Rona Nigromaeulata Breeding Period[J];JOURNAL OF ANHUI AGROTECHNICAL;2000-02
3 Zhang Yi, Xu Zhaochang, Lu Minglian, Chu Yunhong (Department of Chemistry, Bengbu Medical College, Anhui);STUDY OF A CHEMILUMINESCENT IMMUNOASSAY FOR TESTOSTERONE IN BLOOD SERUM[J];Journal of Bengbu Medical College;1993-04
4 LI Chun-Wang JIANG Zhi-Gang ZENG Yan YAN Cai-E (Institute of Zoology,The Chinese Academy of Sciences,Beijing\ 100080,China) ZHANG Lin-Yuan XIA Jing-Shi TANG Bao-Tian (Beijing Milu Park,Beijing\ 100076,China);Velvet tissue estradiol concentrations in Père david's deer,sika deer and fallow deer[J];Acta Zoologica Sinica;2003-01
5 Huang Xingming,Min Xiaoxia,Huang Yurong(Department of Nuclear Medicine of Chengdu Sixth People's Hospital,chengdu 610051);Value of Measurement of Serum FSH、LHⅡ and E2 levels for menopausal women[J];Journal of North Pharmacy;2011-05
6 Han Peizhen; Jin Yueying; Zhang Yingzhen et al.(Instiute of Radiation Medicine, CAMS & PUMC, Tianjin 300192);The Coated Antibody Count RIA for Estradiol and Progesterone[J];Labeled Immunoassays and Clinical Medicine;1998-03
7 SUN You-xiang, XU Li-gen, JIAO Yan (National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050, China);The Establishment of 3,5,3'-Triiodothyronine Working Standard for Immunoassay[J];Labeled Immunoassays and Clinical Medicine;2002-02
8 HAN Cui-hua, LIU Qing, QI Bing, et al. (Department of Nuclear Medicne, 304th Hospital, PLA,Beijing 100037, China);The Changes of β-endorphin,Thyroid Hormone and Cortisol in Military Stress[J];Labeled Immunoassays and Clinical Medicine;2002-03
9 ZHU Cheng-yi, YUAN Xiao-ping (Department of Nuclear Medicine, The First Affiliated Hospital, College of Medical Sciences, Zhejiang University, Hangzhou 310003,China);Effects of Different Incubation Periods on Results of Laminin Measured by RIA[J];Labeled Immunoassays and Clinical Medicine;2002-04
10 XU Li-gen, SUN You-xiang, JIAO Yan (National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050, China);The Establishment of Thyroxine Working Standard for Immunoassay[J];Labeled Immunoassays and Clinical Medicine;2003-01
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 WU Yong-Fang YING Yun MAO Sun-Bo (Wuhan Postgraduate Medical College, Wuhan, 430016);A CLINICAL TRIAL OF THE EFFECTIVENESS OF HYDROXYCAMPTOTHECIN COMBINED WITH SALVIA MITORRHIZA FOR CANCERS OF THE DIGESTIVE SYSTEM[J];Chinese Journal of Cancer;1990-03
2 Zhang Buzheng (Kunming General Hospital of Chengdu Military Region, Yunnan);The Effective Observation and the Mechanism Research on Acute Renal Failure Treated with Danshen[J];;1991-02
3 Jin Shugen (The Affiliated Shuguang Hospital of Shanghai University of TCM, Shanghai);Clinical and Experimental Research on Chronic Hepatic Disease Treated with Rougan Kangxian Decoction[J];China Journal of Traditional Chinese Medicine and Pharmacy;1994-04
4 Yie Yongan(Affiliated Dongzhimen Hospital, Beijing University of Traditional Chinese Medicine and Pharmacology, Beijing);Preliminary Exploration on Hepatic Disease Induced by Alcohol Viewed from TCM[J];China Journal of Traditional Chinese Medicine and Pharmacy;1997-05
5 Niu Dadi,et al Laboratory of Cardiopulmonary Endocrinology;TAURINE INHIBITS VASCULAR SMOOTH MUSCLE CELL PROLIFERATION OF RAT[J];;1993-04
6 Zhang Jinfeng,et al (Department of Chinese Medical Herbs,Affiliated Hospital,Binzhou Medicd College);PRELIMINARY STUDY OF RHIZOMA ZEDOARIAE INHIBITING FIBROBLASTS PROLIFERATION IN VITRO[J];JOURNAL OF BINZHOU MEDICAL COLLEGE;1997-02
7 Liuxianwen, et al.;observation on 189 tragomaschalia cases'clinical results treaed by pu Ye Xiang spray[J];;1994-03
8 Yang Zili, Wang Zhengguo, Zhu Peifang, Bai Tao, Wu Hen (Research Institute of Field Surgery, Daping Hospital, Third Military Medical University, Chongqing,630042);Changes of nitric oxide during cellular damage by endotoxin and its significance[J];ACTA ACADEMIAE MEDICINAE MILITARIS TERTIAE;1997-03
9 Luo Sufang, Zhang Peiwen,Li Ruisong Department of Pharmacology, First Military Medical University;Dilating action of 3 , 4', 5 - trihydroxystibene - 3 -β -mono-D-glucoside on rabbit' s blood vessels[J];Journal of First Military Medical University;1992-01
10 Wang Yaozhong,Huang Zikai,Zhang Peiwen Department of Pharmacology Department of Information, Nanfang Hospital;3,4’,5,trihydroxystibene-3-μ-mono-D-glucoside inhibited rabbitaorta strip contraction induced by histamine released from platelet[J];ACAD J ISI MED COLL PLA;1994-03
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 Liu Yuling , Chen Xiaying , Chen XuLin, et al.Department of Experimental Surgery Laboratory of the First Clinical College in Anhui Medical University , Hefei , 230032;Effect of salvia miltiorrhizae on water content in rats during early postburn stage[J];;2006-03
2 ZHANG Ling1,2,LI Jun1,HUANG Yan1,et al (1.School of Pharmacy,Anhui Medical University,Hefei 230032 China;2.The 4th Affiliated Hospital of Anhui Medical University,Hefei 230022 China);Protective effects of TFC on alcohol-induced acute liver injury in mice and its mechanisms[J];Anhui Medical and Pharmaceutical Journal;2011-10
3 QIAN Yan, LING Chang quan, JIN Yan (Dept. of Traditional Chinese Medicine, Changhai Hospital, Second Military Medical University, PLA, Shanghai 200433,China);INFLUENCE OF GANFUJIAN GRANULE ON COLLAGEN SEDIMENT IN RAT LIVER FIBROSIS[J];Journal of Anhui Traditional Chinese Medical College;2002-04
4 Chen Liangliang,Huang JianfeiZhejiang Provincial TCM Hospital,Hangzhou(310006);Review on the Research of the Effect of Danshen and Its Extract on Tumor Metastasis[J];Journal of Zhejiang University of Traditional Chinese Medicine;2006-04
5 HAN Xiang-bei 1,2,ZHU Tong-tong1,GUO Ya-xiong1,LI De-long1,XU Duo1,CHENG Hong1,ZHANG Wan-xian1*,ZHAO Li-jing1,ZHAO Li-juan1 (1.Department of Pathophysiology,School of Basic Medical Sciences,J ilin University,Changchun 130021,China; 2.Department of Endocrinology,People's Hospital of Jilin Province,Changchun 130021,China);Immunoregulatory effects of Curcumae on acute liver injury induced with CCl_4 in mice[J];Journal of Jilin University(Medicine Edition);2010-05
6 ZHU Xiong Xiang, TANG Chao Wu, CHEN Bi Department of Burn Surgery, Center of Plastic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710033, China;Effect of burn patient's serum and Salvia miltiorrhiza on chemiluminescence magnitude of normal blood polymorphonuclear neutrophils[J];JOURNAL OF THE FOURTH MILITARY MEDICAL UNIVERSITY;1999-10
7 WANG Chun-xia, HOU Lian-bing, MA YunDepartment of Pharmaceutics, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China;Changtong oral liquid for prevention of postoperative intestinal adhesion: an experimental study[J];Journal of First Military Medical University;2005-02
8 WANG Jun dong,LI Shu qin,SHEN Rui ling,WANG Jian ling (College of Animal Science and Veterinary Medicine, Shanxi Agricultural University, Taigu,030801,China);Effects of Four kinds of Chinese Medicinal Recipes on Part Characteristic in Broiler[J];Progress In Veterinary Medicine;2002-04
9 Yuan Gao, Xu-Kang Cheng, Dan Chen Department of Ophthalmology, Wuhan No.1 Hospital, Wuhan 430022, Hubei Province, China;Investigation of prevention effect of tanshinone ⅡA on human pterygium fibroblasts[J];International Journal of Ophthalmology;2011-06
10 Li Zhijun, XIN Jianjun. Affiliated Hospital of Chinese and western medicine school,Anyang City,Henan Province 455000;Therapeutic effect of acupoint injection in treating 42 patients with diabetic neuropathy[J];Hebei Journal of Traditional Chinese Medicine;2001-11
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved