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《Acta Universitatis Medicinalis Secondae Shanghai》 2002-03
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Therapeutic Efficacy of Astragalus in Patients with Chronic Glomerulonephritis

SHI Jun-feng, ZHU Han-wei, Zhang Chong, et al(Department of Nephrology, Xinhua Hospital, SSMU, Shanghai 200092, China)  
To investigate the therapeutic efficacy of astragalus injection on proteinuria as well as to observe the relationship between the efficacy of T - lymphocyte subsets and cytokine receptors in patients with chronic glomerulonephritis. Methods Changes in proteinuria, serum CD3, CD4 and CD8 levels, of CD4/CD8 ratio and serum SIL- 2R, SIL- 6R were determined in 30 patients with chronic glomerulonephritis, before and after treatment with astragalus injection (40ml/d) for 3 weeks. Results Proteinuria dropped from (2328.10 ± 3 157.18)mg/24h to (1 017. 21 ± 765. 39)mg/24h (P 0.01) , CD4 le-vels were lowered from 45.54% ± 8.99% to 40.77% ± 8.30% (P 0.05) , CD8 levels were increased from 25.33% ± 9. 53% to 27. 74% ± 8. 24% (P 0.01) , and the ratio of CD4/CD8 fell from 2. 56 ± 2. 36 to 1. 70 ± 0. 92 (P 0. 05) . There were also significant decreases in serum SIL - 2R from (673.08 ± 451.87)ng/L to (548.95 ± 342.86)ng/L (P 0.05) and SIL - 6R from (43.22 ± 14.39)ng/ L to (36.18± 9.51)ng/L (P 0.05) . Conclusion Astragalus injection can be used safely to alleviate proteinuria and adjust cellular immunological functions in certain patients with chronic glomerulonephritis.
【CateGory Index】: R692.31
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Chinese Journal Full-text Database 2 Hits
1 Chen Zhesheng, Sun Mingjie, et al.(Capital Institute of Medicine, Beijing, 100054);Study on Direct Activation of Radix Astragali seu Hedysari on Human Lymphocyte, and Macrophage and Neutrophil of Mice[J];Chinese Traditional Patent Medicine;1993-06
2 liying,Xie yunhui,etal.Kunming General Hospital of PLA,Kunming 650 0 32;Effects of Astagalus Essence on Serum IL- 6and IL- 8in Patients with Chronic Nephritis Cao[J];ZHEJIANG JOURNAL OF INTEGRATED TRADITIONAL CHINESE AND WESTERN MEDICINE;2000-10
Chinese Journal Full-text Database 10 Hits
1 CHEN Wei dong,JIA ping,ZHANG Yan (Department of Nephrology,Affiliated Hospital of Bengbu Medical College,Anhui 233004 ,China);Effect of Astragalus menbranaceus in treatment of primary nephrotic syndrome[J];Journal of Bengbu Medicinae College;2001-03
3 Wang Xingchi,Liu Weimin,Zhang Jing (Yanxin Peoples Hospital,Yangxin,Shandong 251800);TREATMENT OF ASTRAGALUS MEMBRANCES ZHUSHEYE FOR HEMORRHAGIC FEVER WITH RENAL SYNDROME——A CLINICAL OBSERVATION OF 91 CASES[J];Journal of Binzhou Medical College;2001-01
4 AI Ming-xian,WU Xian-hua, LI Zuo-pin, et al. (Medical College,Hubei Institute for Nationalities,Enshi 445000,China);Protective Effects of 91WID on Leukocyte of ~(60)Co-ray Irradiated Mice[J];Journal of Hubei Institute For Nationalities Medical Edition;2004-01
5 ZHAO Guoqing ,XU Shizheng,LI Suping,et al. Department of Dermatology,People′s Hospital of Wchan University,Wuhan 430060,China.;Mixture injection of Chinese herbal drugs in the treatment of BXSB mouse systemic lupus erythematosus[J];Chinese Journal of Rheumatology;2001-03
6 Wang yong,Hu zhiqian,Chen zhigang,Zhang lingzhen,Wang yuanhe,Department of General Surgery,Chang Zheng Hospital,Second Miliary Medical University.Shanghai 200003;EFFECT OF ASTRAGALUS ON CELLULAR IMMUNE FUNCTION OF RATS WITH OBSTRUCTIVE JAUNDICE[J];JOURNAL OF HEPATOBILIARY SURGERY;2000-01
7 CHEN Zuhong People's Hospital of Beihai City, Guangxi, Beihai 536000;Clinical observation of Danqi Baoshen Jiangtang decoction in treating diabetic nephropathy[J];Hebei Journal of Traditional Chinese Medicine;2005-02
8 Wan Yunli (Tanggu Hospital of Tianjin City, Tianjin, 300450);Therapeutic Observation on Therapy of Supplementing qi and Activating Blood Circulation for 36 Cases of Early Diabetic Nephrosis[J];Henan Traditional Chinese Medicine;2005-01
9 JIN Jiansheng,ZHENG Xiangxiong,LIN Qingyou,et al Department of nephrology,Union Hospital,Fujian Medical University,Fuzhou (350001);Effect of Radix Astragali on sFasL and T Cell Subsets in Patients with Uremia[J];Chinese Journal of Integrated Traditional and Western Nephrology;2002-03
10 XU Gang,YAN Juzhen,SHI Lei, et al.Department of Nephrology,the Hangzhou Second Hospital, Hangzhou 310015,China.;The status of plasma selenium in patients with chronic renal failure and its clinical significance[J];Journal of Clinical Internal Medicine;2003-02
Chinese Journal Full-text Database 10 Hits
1 WANG Hai-Yan △, LI Jing-Zi, PAN Ji-Sheng, ZOU Wan-Zhong, LI Xiao- Mei,ZHANG You-Kang, ZHU Shi-Le, HUANG Hai-Chang, WANG Shu-Xian (Institute of Nephrology, Peking University First Hospital, Beijing 100034,China);The effect of Astragali and Angelica on nephrotic syndrome and its mechanisms of action[J];Journal of Beijing Medical University;2002-05
2 SUN Xing-wang1, CAO Ling2, YU Guo-hua1, TANG Xue-qing1, GUO Qing-xi1, ZHANG Xuan1, WANG Wei1, XU Kai1 (1 Department of Pathology, 2Department of Nephrology, The Affiliated Hospital, Luzhou Medical College, Luzhou 646000, China);Effect of sodium tanshinone Ⅱ-A sulfonate on proliferation and cyclin E expression in human renal interstitial fibroblasts in vitro[J];Acta Academiae Medicinae Militaris Tertiae;2007-07
3 Li Dan-ming,et al. (.Department of Physiology, Lanzhou medical college, Lanzhou,730000);Effects of Dangshen and Danshen on contractile activity of isolated aortic muscle strips in abbits[J];JOURNAL OF GANSU COLLEGE OF TRADITIONAL CHINESE MEDICINE;2000-02
4 Ning Yaoyu,Ke Meizhen,Zhou Xiaoling,et al(Department of Pathophysiology,Guangxi Medical University,Nanning\ 530021);EFFECTS OF AEROSOL INHALATION OF HOUTTUYNIA CORDATA THUNB EXTRACT ON THE IMMUNOLOGICAL FUNCTIONS IN RATS[J];ACTA ACADEMIAE MEDICINAE GUANGXI;1997-04
5 Gui Huazhen ,etal Departmentof pathophysiology, Guiyang Medicalcollegen;The Influence of Man Shen Kang on the matrix Components of Fibrotic Kidney[J];Journal of Guiyang Medical College;1999-04
6 Pei Ren-jiu; Xiao Ling; Fan Xiao-pin;Liu Xi-jun(Dept. of clinical pharmacology,Fuzhou General Hospital of Nanjing Armed Forces,Fuzhou);The Effects of Matrine on Mouse Immune Functions[J];STRAIT PHARMACEUTICAL JOURNAL;1998-02
7 Chen Hong(Fuzhou Meifeng Pharmaceutical Factory)Yu Xiangbin;Fang Chuanzhi;Liu Xijun(Fuzhou General Hospital of Nanjing Military Fuzhou);The Study for in Vivo Effects of Matrine on Lipopolysaccharides (LPS)[J];STRAIT PHARMACEUTICAL JOURNAL;1999-04
8 Zhou Yunfeng, Wu Yong, Ouyang JingpingDept. of Pathophysiology, School of Medicine, Wuhan University,Wuhan 430071, China;Effects of Astragalus Polysaccharide on Insulin Signal Transduction in Renal Tissue of Type 2 Diabetic Rats[J];Journal of Hubei Medical University;2005-02
9 Zhang Cui, Zhu Yu (1.Dept. of Traditional Chinese medicine. Heilongjiang Institute of Commerce, Harbin, 150076,China: 2.No. 211 Hospital of the PLA People's Liberation Army, Harbin, 150080. China);Effect of Heamorheology Change on Patients Suffering from Chronic Renal Corpulse Nephritis[J];Journal of Heilongjiang Commercial College (Natural Sciences Edition);2000-01
10 Li Wenguang, Zhan Zhinong, Zhou Zhenjian (Laboratory of microbiology and Immunity, Hainan Medical College) Haikou 571101;ANTIBACTERIAL EFFECTS OF RADIX SOPHOPRAE FLAVES-CENTIS TABLET IN VITRO[J];Journal of Hainan Medical College;2001-02
【Secondary References】
Chinese Journal Full-text Database 2 Hits
1 ZHONG Yue-ping(The Maternal and Child Care Service Centre of Qinzhou,Guangxi Zhuang Autonomous Region,Guangxi Qinzhou 535000,China);Clinical Application of Radix Astragali Preparation in Pediatrics[J];Journal of Pediatric Pharmacy;2009-05
2 YUAN Yi1,WANG Jia-chun2,WANG Zheng3,CHU Zhi-yong2,WANG Xu-hui1,SHEN Yue2,ZHANG Shu2,LUAN Jie2(1.Department of Pharmacy,Central Hospital of Putuo District,Shanghai,200062,China;2.Naval Medical Research Institute of PLA,Shanghai 200433,China;3.Qingfengge Pharmaceutical Science and Technology Co.Ltd,Shanghai 200092,China);Study on mechanism of action of Zhixiao Tongmaining granules on diabetic nephropathy[J];Journal of Pharmaceutical Practice;2009-04
【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
1 .TangDeshen,TangBin,LiuHuafeng,etal.RenalInstitute,AffiliatedHospitalofGuangdongMedicalColege,Zhanjiang524001;DeterminationofIL┐8fromserumandurineinpatientswithchronicrenalfailure[J];CHINESE JOURNAL OF NEPHROLOGY;1996-06
2 Gao Mei,et al. Department of Immunology, Beijing Medical University, Beijing 100083, China;The enhancing effect of Polyporus Umbellatus Polysccharide on immunological functions of mice[J];Chinese Journal of Immunology;1991-03
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