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《Journal of Shanghai Jiaotong University(Medical Science)》 2012-04
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Colposcopic cervical biopsy and pathology after loop electrosurgical excision procedure in diagnosis of cervical diseases

YANG Feng-yun,YANG Bo,GU Ping,HU Rong,ZHU Mei-juan,CAO Yun-gui,GAN Xiao-wei(Shanghai Jiading District Maternal and Child Care Service Center,Shanghai 201800,China)  
Objective To investigate the values of colposcopic cervical biopsy,pathology after loop electrosurgical excision procedure(LEEP) and the combined examinations of colposcopic cervical biopsy and LEEP in the early diagnosis of cervical precancerous lesions and cervical cancer.Methods Five hundred and fifty-four patients with abnormal findings in cervical cytology and/or human papillomavirus(HPV) test or with normal findings in these screening tests while having moderate to severe cervical columnar eversion were subject to colposcopic cervical biopsy and LEEP,and the pathological findings were compared before and after LEEP.Results The total coincidence rate of colposcopic cervical biopsy and pathology after LEEP was 49.82%.In patients diagnosed as cervical intraepithelial neoplasia(CIN) Ⅰ by cervical biopsy,14.36% were diagnosed as CINⅡ/Ⅲ after LEEP.In patients diagnosed as CIN Ⅱ/Ⅲ(including carcinoma in situ) by cervical biopsy,3.89% were diagnosed as invasive carcinoma after LEEP.Kappa coefficient was 0.62 in the consistency of diagnosis of CINⅡ/Ⅲ by two methods.Kappa coefficient was 0.80 in the consistency of diagnosis of CINⅡ/Ⅲ by colposcopic cervical biopsy and combined examinations of colposcopic cervical biopsy and LEEP,and that was 0.84 by pathology after LEEP and combined examinations of colposcopic cervical biopsy and LEEP.The total accuracy of colposcopic cervical biopsy was 81.77%,and the misdiagnosis rate of CINⅡ/Ⅲ was 20.64%.Conclusion Colposcopic cervical biopsy and pathology after LEEP are effective measures for diagnosis of CIN and microinvasive cervical carcinoma.Colposcopic cervical biopsy may misdiagnose high-level CIN and microinvasive cervical carcinoma,and the combined examinations can improve the accuracy of diagnosis.
【Fund】: 上海市嘉定区卫生局青年基金(ZD02 QNKYJJ20081106)~~
【CateGory Index】: R737.33
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【References】
Chinese Journal Full-text Database 3 Hits
1 GENG Xiao-hui.The First Maternal and Child Health Care Hospital of Huizhou City,Huizhou 516000,Guangdong Province,China;LI Hong-yan Chencun Hospital of Shunde District of Foshan City in Guangdong Province,Foshan 528300,Guangdong Province,China;Value of "See and Treat" Method in the Diagnosis and Treatment of Cervical Intraepithelial Neoplasia[J];Journal of International Reproductive Health/Family Planning;2013-03
2 LIAO Qingmei WANG Wei HUANG Haili Department of Gynecology,Shenzhen City Nanshan District Women and Children Health Care Hospital,Shenzhen 518000,China;Value in the diagnosis of colposcopic cervical biopsy and cervical loop electrosurgical excision procedure for cervical lesions[J];China Modern Doctor;2013-03
3 HUANG Bai-li1, LI Xiu-fang2 (1.Departments of Gynecology, Maternal and Child Health Hospital of Zhuji, Zhuji, Zhejiang 311800, P.R.China; 2.Department of Pathology, the First People's Hospital of Zhuji City, Zhuji, Zhejiang 311800, P.R.China);Significance of LPT, colposcopy and expression of PTEN and ki-67 in early diagnosis of cervical carcinoma[J];China Journal of Endoscopy;2013-05
【Citations】
Chinese Journal Full-text Database 4 Hits
1 Zhang Xun 1 ,Li Ling 1 ,Zhang Wen-Hua 2 ,Li Shu-Min 2;Evaluation of Cold Knife Conization(CKC)on Diagnosis and Treatment of Cervical Intraepit helial Neoplasia[J];Chinese Journal of Cancer;2003-09
2 LUO Chunfang,ZHANG Chun,WANG Hui,et al(The Third Hospital of Wuhan,Wuhan Hubei 430060,China);Colposcopy Colposcopically Directed Biopsy and LEEP in the Diagnosis of Cervical Intraepithelial Neoplasia[J];Journal of Practical Obstetrics and Gynecology;2009-09
3 SUI Long, WANG Qing, ZHENG Rui-lian,CHEN Min, XIE Feng, DIAO Wen-Jing, FEN You-ji (Diagnosis and Treat Center for Cervical Disease, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011,China );Reappraisal on mild cervical intraepithelial neoplasia based on punch biopsy and colposcopical diagnosis through cervical conization by LEEP[J];Fudan University Journal of Medical Sciences;2006-06
4 L Wei-guo, SHEN Yuan-ming, YE Feng,CHEN Huai-zeng, XIE Xing. Department of Gynecologic Oncology, Women′s Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China Corresponding author: XIE Xing, Email:xiex@mail.hz.zj.cn;The accuracy of diagnosing cervical intraepithelial neoplasia with colposcopically directed biopsy[J];National Medical Journal of China;2006-05
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Department of Obstetrics and Gynecology,The fourth People's Hospital of Tongling City, Tongling 244000, Anhui NIU Yu-min,ZHU Tao-hua;Analysis of Repeated Pregnancy and Childbearing with Cicatrical Womb[J];Journal of Anhui Health Vocational & Technical College;2009-02
2 Chaohu Vocational and Technical College,Chaohu 238000,Anhui XU Rong-rong;Primary Factor Analysis and Measures of the Rise in Caesarean Section Rate[J];Journal of Anhui Health Vocational & Technical College;2009-04
3 Department of ohstetrics and Gynecology, Anhui Provincial Xin'an Hospital, Hefei 230001, Anhui SUN Yang-chun;A Clinic Analysis on 67 Cases of Adenomyosis[J];Journal of Anhui Health Vocational & Technical College;2009-05
4 Department of gynecology and obstetrics in People's Hospital of Xuancheng,Xuancheng 242000,Anhui XU Qing-xian,CHENG Min;Clinical analysis of 96 cases of endometriosis[J];Journal of Anhui Health Vocational & Technical College;2010-03
5 ZHANG Ben-shun General Miner Hospital of Huaibei Mining Industry Company,Huaibei 235000,Anhui;Clinical Analysis of Conservative treatment to 17 Cases Placenta Increta[J];Journal of Anhui Health Vocational & Technical College;2011-04
6 QIAN Yu-jing Anhui Medical College Affiliated Hospital,Hefei 240022,Anhui;Study on the obsterics factors for neonatal asphyxia and its prevention[J];Journal of Anhui Health Vocational & Technical College;2011-04
7 Lin Cuncheng, Zheng Jianqiong, Huang Guosheng The Third Hospital of Wen Zhou ,Wen Zhou 325000;Correlation of psychological states and estrogen level in hystromyoma patients before operation[J];Anhui Medical Journal;2008-06
8 Fu Liutao The Fourth People's Hospital of Tongling,Tongling 244000;Analysis on perinatal outcomes of intrahepatic cholestasis pregnancy in 77 patients[J];Anhui Medical Journal;2009-11
9 Wang Ping Department of Gynecology and Obstetrics,Bengbu Third People's Hospital,Bengbu 233000,China;Clinical study of postpartum vaginal lactobacillus application[J];Anhui Medical Journal;2010-02
10 Fu Xiaobing Department of Obstetrics and Gynecology,Tiesiju central Hospital,Hefei 230000,China;Different time-limits the end of the analysis of the ICP occurrence of pregnancy[J];Anhui Medical Journal;2010-07
China Proceedings of conference Full-text Database 5 Hits
1 XU HUIJUN~1,YANJIANMIN~2,TAIGUOXIANG~1,LINJING~1 1.Hiser Medcial Center of Qingdao 266033;2.XiyuanHospital,China Academy of Chinese Medical Sciences;Clinic observation and study on Jiajianyijing tang in treating Premature ovarian failure[A];[C];2011
2 YANG Fan YANG Tai-zhu ZHU Qi LUO Hong TIAN Yu CHEN Jiao (Department of Diagnostic Ultrasound, The 2~(md)HUAXI Hospital of Sichuan University, ChengDu, 610041);Sonographic diagnosis of ovarian fibromas[A];[C];2008
3 ;妇科住院腹部手术疾病分类构成帕累托图及住院时间分析[A];[C];2010
4 ;A study on effects of the recipe of Yiqi Huoxue Shengjion mice taking cesarean section[A];[C];2009
5 Yin Ge-ping, ZhuTong-yu,Chen Ming,Yang Shu-jun,Li Juan,Zhao Xiao-li,Zhao Xiu-e(Department of Gynecology,Jinan Militrary General Hospital,Jinan 250031,China.);Expression and significance of Survivin and Ki67 markers before and after loop electrosurgical excision procedure of cervical intraepithelial neoplasia[A];[C];2012
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 TANG Wei-qing,YANG Xiu-li,CHEN Shu-kui(Department of Gynecology and Obstetrics,Affiliated Hospital of Guangdong Medical College,Zhanjiang 524001,China);Clinical features of cervical intraepithelial neoplasia and diagnostic significance of colposcopy:report of 263 cases[J];Journal of Guangdong Medical College;2011-01
2 LI Liping,SU Luxian,WU Chengyong,et al(Meizhou People's Hospital,Guangdong Meizhou 514003,China);Analysis the Epidemiologic Distribution of Human Papilloma Virus(HPV) Genotypes in Meizhou Area[J];Hebei Medicine;2011-12
3 XU Guo-rong1,ZENG Ying2,XIONG Shu-hua2 (1.2007 Grade of Medical Department,Graduate School of Nanchang University; 2.Department of Oncology,Jiangxi Maternal and Child Health Hospital,Nanchang 330006,china);Value of Colposcope in Diagnoses of Early Stage Cervical Cancer and Precancerous Lesion[J];Practical Clinical Medicine;2009-04
4 CHENG Jianying WANG Haixia ZHAO Junhong Department of Obstetrics and Gynecology, Jinshan Hospital, Fudan University, Shanghai 200540;Comparison of Three Methods in the Diagnosis of Cervical Intraepithelial Neoplasia[J];Chinese Journal of Clinical Medicine;2009-02
5 WANG Ling WU Hong YAO Hongxia XU Jing First Maternal and Infants Hospital of Tongji University,Shanghai 200040,China;Clinical Application of See-and-Treat Strategy for Diagnosis and Management of High-grade Squamous Intraepithelial Lesions[J];Chinese Journal of Clinical Medicine;2010-02
6 HUANG Yan,LI Chunmei,LIANG Baoquan,et al(West China Second University Hospital,Sichuan University,Chengdu Sichuan 610041,China) Corresponding author:LI Chunmei;Relationship between Characterictics of Cervical Images by Electronic Colposcopy and Pathological Results after Biopsy in 260 cases of Cervical Diseases[J];Journal of Practical Obstetrics and Gynecology;2012-05
7 DENG Xiu-juan,WU Hai-gen.2009 Grade of Medical Department of Graduate School,Nanchang University,Nanchang,330006;The Expression and its Clinical Significance of Ki67 and PTEN in Ovarian Serous Tumor[J];The Practical Journal of Cancer;2011-04
8 ZHANG Guanyu1,XU Lili1,WANG Jianqin1,SUN Fengjuan2,HAN Jiping2 1.Department of Pathology,Liaohua General Hospital of Liaoyang City,Liaoning Province,Liaoyang 111003,China;2.Department of Obstetrics and Gynecology,Liaohua General Hospital of Liaoyang City,Liaoning Province,Liaoyang 111003,China;Liquid-based cervical cytology and expression of Ki-67 and PTEN in the clinic significance of cervical intraepithelial neoplasia[J];China Medical Herald;2011-28
9 LIANG Chun-yan,HUANG Yan-ping (Department of Obstetrics and Gynecology,the First People's Hospital of Shaoguan,the Affiliated Shaoguan Hospital of Guangdong Medical College,Shaoguan 512000,China);Clinical Value of Vaginal Cancer Diagnosis of Early Mirror with Pre-cancerous[J];Guide of China Medicine;2010-19
10 XU Gen'er,XIA Xiaoqin(Zhejiang Fuyang Maternal and Child Health Care Hospital,Hangzhou,Zhejiang 311400,P.R.China);Clinical analysis of 209 cases of cervical biopsy punched under the instruction of colposcopy[J];China Journal of Endoscopy;2009-01
【Secondary Citations】
Chinese Journal Full-text Database 6 Hits
1 ZHAO Lifen,ZHU Xiaohua,WU Xiaomin (The Central Hospital of Lishui City,Lishui Zhejiang 323000,China);Loop Electrosurgical Excision Procedure for the Treatment of Cervical Intraepithelial Neoplasm:a Valuable Study of 212 Cases[J];Journal of Practical Obstetrics and Gynecology;2006-08
2 HE Chunnian,XU Cuiqing,ZHAO Huanfen,et al.(Hebei Provincial People's Hospital,Shijiazhuang Hebei 050051,China);Pathological Grading and Treatment to CIN and Cervical Squamous Cell Carcinoma[J];Journal of Practical Obstetrics and Gynecology;2007-08
3 SUI Long, WANG Qing, ZHENG Rui-lian,CHEN Min, XIE Feng, DIAO Wen-Jing, FEN You-ji (Diagnosis and Treat Center for Cervical Disease, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011,China );Reappraisal on mild cervical intraepithelial neoplasia based on punch biopsy and colposcopical diagnosis through cervical conization by LEEP[J];Fudan University Journal of Medical Sciences;2006-06
4 SHEN Keng, LANG Jinghe, HUANG Huifang,et al. Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, China;Evaluation of cervical conization in diagnosis and management of cervical intraepithelial neoplasia[J];Chinese Journal of Obstetrics and Gynecology;2001-05
5 FAN Qingbo *, TAY Sun Kuie,SHEN Keng. *Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, China;Loop electrosurgical excision procedure: a valuable method for the treatment of cervical intraepithelial neoplasia[J];Chinese Journal of Obstetrics and Gynecology;2001-05
6 L Wei-guo, SHEN Yuan-ming, YE Feng,CHEN Huai-zeng, XIE Xing. Department of Gynecologic Oncology, Women′s Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China Corresponding author: XIE Xing, Email:xiex@mail.hz.zj.cn;The accuracy of diagnosing cervical intraepithelial neoplasia with colposcopically directed biopsy[J];National Medical Journal of China;2006-05
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