Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Shanxi Journal of Traditional Chinese Medicine》 2015-04
Add to Favorite Get Latest Update

Experimental Study of Animal Acute Toxicity and Skin Stimulating by Zhenshi Jiuwei Ointment

CHEN Hong-yan;Hebei Province Hospital of Traditional Chinese Medicine;  
Objective:To reserch animal models ccute toxicity and skin stimulating induced by Zhenshi Jiuwei ointment,and evaluate the safety of the drug. Methods:To applyind Zhenshi Jiuwei ointment on the intact skin and the damaged skin of the rat models,The toxicity and body weight were observed. To applyind zhenshi Jiuwei ointment on the intact skin and the damaged skin of guinea pig models,By self-control of left andright side after single and multiple administration,to observe the skin stimulating reaction on the skin. Results: In acute toxic test,Zhenshi Jiuwei ointment had no acute toxicity to rats;and no significant effect on body weight,compared with control group. In skin stimulatiny test,there were no skin stimulation on the intact skin of guinea pigs,and had no erythema and edema;there had no obvious skin Stimulation on the damaged skin,and the skin stimulation disappeared after 24 h. Conclusion: In a certain dose,Zhenshi Jiuwei ointment has no acute toxicity on the rats,has no skin stimulating on the guinea pigs.
【CateGory Index】: R285.5
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 2 Hits
1 ZHANG Qing-qing, YU Sheng-min, HUANG Lin-yun, GUO Li-cheng, DENG Ru-ming(Guangxi Academy of Minority Nationality Medicine and Pharmacology,Guangxi Zhuang Medicine Hospital,Nanning 530001,China);Experimental Study On Skin Irritation of Zhuangyao Xianghua Hufu Gel[J];Lishizhen Medicine and Materia Medica Research;2013-02
2 ZHANG Xu-hui1, LIN Han2, DONG Jian-xun2, LI Jian-rong3, LU Yan-li3, ZHAO Guang-ming1, LI Yuan1,HUANG Feng1,KONG Xiao-li2(1.Beijing University of Chinese Medicine,Being 100029,China;2.Beijing Hospital of Chinese Medicine Affiliated to Capital Medical University,Beijing 100010,China;3.Insitute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China);Experimental Study of Animal Acute Toxicity and Cutaneous Stimulation Induced by Zhuhong Ointment[J];Chinese Journal of Information on Traditional Chinese Medicine;2012-09
【Co-citations】
Chinese Journal Full-text Database 1 Hits
1 MA Wei-na;GU Fu-gen;School of Pharmacy,Inner Mongolia Medical University;Affiliated Hospital of Inner Mongolia Medical University;;Research progress of pharmaceutical gel[J];Practical Pharmacy and Clinical Remedies;2014-12
【Secondary Citations】
Chinese Journal Full-text Database 7 Hits
1 DONG Jian-xun1, WANG Le-ping2, LI Jian-rong3, LUO Ling2, HE Rong3, PENG Bo3, XU Qi-hua3, GAO Jie3, LU Yan-li3(1Beijing Hospital of Chinese Medicine, Capital Medical University, Beijing 100010, China; 2Beijing University of Chinese Medicine, Beijing 100029, China; 3Institute of Chinese Materia Medica, China Academy of Chinese Medical Science, Beijing 100700, China);Toxic target organ and safe dose range of Zhuhong Ointment[J];China Journal of Traditional Chinese Medicine and Pharmacy;2011-06
2 WANG Le-ping1,DONG Jian-xun2,LUO Ling1,LI Jian-rong3,HE Rong3,PENG Bo3,XU Qi-hua3,LIN Han2,ZHANG Xu-hui1(1Beijing University of Chinese Medicine,Beijing 100029,China;2Beijing Hospital of Chinese Medicine,Capital Medical University,Beijing 100010,China;3Institute of Chinese Materia Medica,China Academy of Chinese Medical Science,Beijing 100700,China);Detecting the sensitive indicators NAG and RBP of toxicity for early kidney tubular injury caused by Zhuhong Ointment[J];China Journal of Traditional Chinese Medicine and Pharmacy;2011-10
3 Mao Kechen, Li Weimin, Li Yang, et al (Beijing Hospital of TCM, Beijing 100010);The Research on Quality Content of Zhuhong Gao[J];Chinese Journal of Information on TCM;2003-04
4 DONG Jian-xun1,LUO Ling2,LI Jian-rong 3,WANG Le-ping 2,HE Rong 3,PENG Bo 3,XU Qi-hua 3(1.Beijing Hospital of Chinese Medicine, Capital Medical University,Beijing 100010,China;2.Beijing University of Chinese Medicine,Beijing 100029,China; 3.Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China);Safety Study on Zhuhong Ointment of Promoting Dermal Ulcer Healing[J];Chinese Journal of Information on Traditional Chinese Medicine;2011-06
5 LIU Mei,DANG Xueliang,WANG Qingwei,YANG Mengmeng,ZHANG Yan Department of Pharmacy,Tangdu Hospital of Fourth Military University,Shaanxi Province,Xi'an 710038,China;Observation of skin irritation experiment in guinea pigs with Compound Resina Draconis Microemulsion[J];China Medical Herald;2011-31
6 Fang Hegui( Zhejiang hospital, Hangzhou, Zhejiang 310013);A External Dosage Form Suitable for Traditional Chinese Medicine——Gel Preparation[J];China Pharmaceuticals;2002-08
7 Lü Peiwen,Zhang Cang,Song Xiao yu,et al Beijing Hospital of Traditional Chinese Medicine,Beijing(100010),China;Clinical Study of Zhuhong(朱红) Ointment in Treating Chronic Skin Ulcer[J];Chinese Journal of Surgery of Integrated Traditional and Western Medicine;2003-05
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved