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《Shanghai Journal of Stomatology》 2004-04
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The effect of static magnetic field on bone morphogenetic protein-2 in periodontal membrane of the rat

QIN Ke,QIU Li-hong, ZHONG Ming,WANG Zhao-yuan.( College of Stomatology, China Medical University.Shenyang 110002, Liaoning Province, China)  
PURPOSE: The purpose of this study is to evaluate the effect of static magnetic field on the expression of BMP-2 in the periodontal membrane of rat. METHODS: 35 female rats of wister were randomly divided into three groups, which were the normal group, experimental control group and experimental group. The experimental rat' s cheeks were put into magnet with the intensity of magnetic field being 0.12 tesla. The rats were sacrificed at 2 days, 4 days, 7 days, respectively. Immunohistochemical assays were used to evaluate the changes of BMP-2 expression in the periodontal membrane of the maxillary molars. RESULTS: BMP-2 was mainly found in the plasma of fibroblast, osteoblast, cementocyte, odontoblast separately. There were more BMP-2 in the experimental group treated with static magnetic field. There were significant differences between the experiment group of 4 day and 7 day and the control group. CONCLUSIONS: Static magnetic field stimulated BMP-2 secreted by the cell of periodontal membrane and played an important role in repairing and remodeling of periodontitis.
【Fund】: 辽宁省教育厅基金(20122170)
【CateGory Index】: R781.4
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