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《》 2005-03
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The diversity of KIR gene content and haplotype analysis in Xinjiang Uygur and Yunnan Yi populations in China

CHI Yong-bin, ZHANG Lei, YANG Jue-qin, YAO Fang-juan, XU Ling-di, Fan Li-an (Shanghai Institute of Immunology, Shanghai Second Medical University, Shanghai 200025, China)  
To detect the diversity of KIR gene content and the combination of haplotypes in Xinjiang Uygur,Yunnan Yi populations in China, DNA samples from randomly unrelated healthy individuals in Xinjiang Uygur, Yunnan Yi minority are genotyped by SSP/PCR method. All results were compared with each other, and significance of values were assessed by χ2 analysis. Sixteen KIR genotypes have been detected in Uygur population, among which AH (5, 2) was the most common genotype, with the frequency of 22.7%, the later were AF (1, 2) and M(2, 8), with the frequency of 13.7%, 9.09%, respectively. Among Yi population, 21 genotypes have been detected, among which AJ (2, 2) was the most common genotype, with the frequency of 33.3%, the next was AF (1, 2), with the frequency of 17.5%. Furthermore, 8 new genotypes have been found among Xinjiang Uygur, Yunnan Yi minority populations, seven of these genotypes could not be analyzed with the existing 23 heplotypes. These findings suggest that there are distinctive frequencies of KIR gene content and haplotypes, as well as the genotypes in Chinese Xinjiang Uygur, Yunnan Yi minorities.
【Fund】: 国家自然科学基金资助项目(30371350) 上海市科委重点项目(02DJ14054)
【CateGory Index】: Q987
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【References】
Chinese Journal Full-text Database 1 Hits
1 ZHANG Yan1,LIU Sheng1,YE Shi-Hui1,LIU Meng-Li1,SHEN Chun-Mei1,QI Jun1,WANG Bo2 1Department of Blood Group Research,Shaanxi Blood Center,Xi'an 710061,China,2Department of Epidemiology,School of Preventive Mediline,Fourth Military Medical Universty,Xi'an 710033,China;Analysis of killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia[J];Journal of the Fourth Military Medical University;2009-17
【Citations】
Chinese Journal Full-text Database 1 Hits
1 ZHANG Lei 1, Katharine C.H su 2, Xiao-Rong LIU 2, YANG Jue-qin 1, YAO Fang-juan 1, XU Ling-di 1, Bo Dupont 2, FAN Li-an 1. 1(Shanghai Second Medical University, Shanghai Institut e of Immunology, Shanghai,200025 P.R. China. ); 2 (Memorial Sloan-Ketteri ng Cancer Center, New York, U S A);Killer Ig-like receptor gene content diversity and haplotype analy sis in Chinese Han population in Shanghai[J];Chinese Journal of Medical Genetics;2003-05
【Co-citations】
Chinese Journal Full-text Database 6 Hits
1 SU Pincan1,YANG Tonghan2,ZOU Hai3,et al.1.Institute of Blood Transfusion,Chinese Academy of Medical Sciences,Chengdu 610081,China;2.Yunan Kunming Blood Center;3.Sichuan Umbilical Cord Blood Bank;Polymorphism of killer cell immunoglobulin-like receptors gene in Yunnan Han population,China[J];Chinese Journal of Blood Transfusion;2008-04
2 HE Cheng-tao1,LI Li1,2,ZHANG Jian-qiong3,et al.(1.Department of Laboratory Medicine,Clinical Medical College of Southeast University,Nanjing 210009;2.Department of Immunology Laboratory,Zhongda Hospital,Southeast University,Nanjing 210009;3.Key Laboratory of Developmental Genes and Human Diseases,Ministry of Education,Nanjing 210009,Jiangsu,China);Polymorphism of killer-cell immunoglobulin-like receptor gene family in Han blood donors in Jiangsu[J];Chinese Journal of Clinical Laboratory Science;2009-03
3 ZHANG Lei,FAN Li-an,YANG Jue-qin,YAO Fang-juan,XU Ling-di(Shanghai Institute of Immunology,Shanghai Second Medical University,Shanghai 200025,China);Diversity of KIR2DL5 Gene Subtype Content and Haplotype Analysis in Chinese Han Population in Shanghai Arca[J];;2004-03
4 XU Jin-huan,ZHANG Jian-qiong,PAN Ning,JIANG Wei,MIAO Feng-qin,XIE Wei(Basic Medical Science School,Southeast University,Nanjing 210009,China);Polymorphism of the immunoglobulin-like receptors gene in killer cells of Chinese Han population[J];Current Immunology;2009-04
5 ZHENG Rui-rui, YE Yun-bin, CHEN Qiang;Killer Cell Ig-like Receptor and Tumor Immunotherapy[J];Bulletin of Chinese Cancer;2006-01
6 JIANG Kan~*, ZHU Fa-ming, ZHANG Wei, L Qin-feng, HE Ji, FU Qi-hua, YAN Li-xing. The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China;The establishment of PCR-SSP method for killer cell immunoglobulin-like receptor gene family and its application[J];Chinese Journal of Microbiology and Immunology;2005-12
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 GONG Wei juan,YANG Jue qin,ZHANG Lei,YAO Fang juan,FAN Li an.Shanghai Second Medical University,Shanghai Institute of Immunology,Shanghai 200025,China;Association of killer cell immunoglobulin-like receptor gene polymorphisms with seronegative spondylarthropathies[J];Chinese Journal of Rheumatology;2003-08
2 XU Ling-di,LU Yu,ZHANG Lei,YANG Jue-qin,YAO Fang-juan,FAN Li-an,Shanghai Institute of Immunology,School of Medicine,Shanghai Jiaotong University,Shanghai 200025,China;Association of killer cell immunoglobulin like receptor (KIR) gene polymorphism with Behcet's disease[J];Chinese Journal of Rheumatology;2006-03
3 LU Bei-yan,HU Yu-hong,LI Wei (The First Affiliated Hospital, Jiamusi University,Jiamusi 154003,China);Alternation in biologic characteristics of natural killer cells in pregnancy induced hypertension[J];Heilongjiang Medicine and Pharmacy;2005-04
4 Zhang Jian (The International Peace Maternity and Child Health Hospital of the China Welfare Institute, Shanghai 200030);Etiological Study of Early Recurrent Spontaneous Abortion[J];Clinical Medical Journal of China;2003-04
5 VAN Wei-hua (Shanghai Institute of Immunology, Shanghai Second Medical University, Shanghai 200025, China);Structure and function of NK cell receptor KIR2DL4[J];Immunological Journal;2003-S1
6 YIN Xiao-lin(Department of Haematology, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China);Evolution,expression,and function of killer immunoglobulin-like receptor gene[J];Immunological Journal;2004-S1
7 ZHANG Lei,FAN Li-an,YANG Jue-qin,YAO Fang-juan,XU Ling-di(Shanghai Institute of Immunology,Shanghai Second Medical University,Shanghai 200025,China);Diversity of KIR2DL5 Gene Subtype Content and Haplotype Analysis in Chinese Han Population in Shanghai Arca[J];;2004-03
8 ZHOU Guang-Jin, YU Long, ZHAO Shou-Yuan(Institute of Genetics, Fudan University, Shanghai 200433, China);The pseudogenes of human genome[J];Chinese Bulletin of Life Sciences;2004-04
9 Zhao Xiangyu,Huang Xiaojun.Peking University Institute of Hematology,People's Hospital,Beijing 100044,China.;Research into the expression of KIR on NK and T cells after HLA-mismatched hematopoitic cell transplantation[J];Chinese Journal of Practical Internal Medicine;2006-08
10 LOU Zi-chang(Department of Politics and History,Wenshan Teachers' College,Wenshan,Yunnan 663000,China);A Reconsideration of the Dominant Race in Ancient Dian kingdom's[J];Journal of Wenshan Teachers College;2006-02
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