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《ACTA BIOCHIMICA ET BIOPHYSICA SINICA》 1995-03
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Influence of Exhaustive Exercise on Fluidity and Complex I of Heart Inner-mitochondrial Membranes in Rats

ZHANG Yong,;LI Jing-Xian; CHEN Jia-Qi and ZHANG Feng-De(Research Institute of Sports Medicine, Tianjin Institute, of Physical Education, 300381;Department of Biology, Naki University,Tianjin 300071)  
Rats running with incremental intensity fo exhaustion were used as a model to investigate the influence of exhaustive exercise on heart inner-mitochondrial membranes(IMM). It was found that, in exhausted rats, the mioroviscosity of IMM increased by 74.4%(meaning a decrease of fluidity), the activity of NADHCoQ rednotase in the respiratory chain declined by 38.4%and the lipid peroxidation metabolite, malondialdehyde (MDA) increased by 39.4%in mitchondria. The result suggested that the exercise-induced increase of lipoperoxide may be responsible for changes of membranous molecular dynamics and function of complex I.
【CateGory Index】: Q731
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