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《Injury Medicine(Electronic Edition)》 2015-04
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Levels of Electrolytes in the Early Days of Neonates with Hypoxic Ischemic Encephalopathy (HIE) Predict the Outcome at Dismiss

MA Xing-wei;FANG Xiao-yi;LUO Dong-ling;CHEN Pei-qun;LIN Ni-yang;Pediatric Department of the First Affiliated hospital of Shantou University Medical College;  
Objective To explore the prognostic value of serum calcium,sodium and potassium levels of neonates with hypoxic ischemic encephalopathy(HIE),as well as the hospitalization days on the outcome of the patients.Methods 300 cases of neonates with HIE were included and grouped according to their clinical features.Serum levels of calcium,sodium and potassium were measured on the 2nd,3rd and 4th day after birth,respectively.Neonatal behavioral neurological assessment(NBNA) was done during days 12th~14th after birth to evaluate the outcome of the neonates.The cut off point is NBNA=35. 35 indicates a favorable prognosis whereas ≤ 35 implies a poor prognosis.Hospitalization days were documented when a HIE neonate was dismissed.50 cases of physiologic neonatal jaundice were used as the controls.Person analysis was performed to calculate the coefficients between levels of serum electrolytes and NBNA scores.Results Levels of serum calcium and sodium in neonates with HIE was positively correlated with the NBNA scores of them(P0.01).The levels of these serum electrolytes were also significantly different among the different groups of HIE neonates(P0.01).Conclusions Levels of serum calcium and sodium can be used to predict the outcomes of neonates with HIE,with the advantages of economic and easy to be measured.
【CateGory Index】: R742
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3 Huang Ying;Zhou Xiaoping;Liao Qianxiu;Department of Laboratory Medicine,Chengdu First People's Hospital;;The clinical value of cord blood cortisol determination in evaluating neonatal hypoxic-ischemic encephalopathy[J];实用检验医师杂志;2017-04
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