Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Shanghai Medica(University)》 2003-05
Add to Favorite Get Latest Update

The Effects of β-elemene on Caspase Activity and Expression of Survivin and Apoptosis of Human Gastric Carcinoma SGC-7901 Cell

GUAN Wen-ming,FAN Yu△,GUO Xue-liang△,LIN Geng-jin△,QIAN Li-ping△,XU Zu-de △△,LI Hua △△(Department of Internal Medicine,Second Hospital,Luohe,Henan Province,462000; △Department of Gastroenterology,Huashan Hospital,Fudan University,Shanghai 200040, △△Department of Pathology,Shanghai Medical Science,Fudan University,Shanghai 200032,China)  
Purpose To study the expression of Survivn and Caspase activity of human gastric carcinoma cell line SGC-7901 treated with β-elemene,and to investigate the mechanism of β-elemene to induce tumor cell's apoptosis. Methods After gastric cancer SGC-7901 cell were treated with different doses β-elemene,the protein and mRNA level of Survivn were detected by Western blot as well as Northern blot respectively,Caspase activity were evaluated by microplate reader,apoptosis were studied by TUNEL. Results β-elemene could down-regulate the level of protein and mRNA of Survivn,and elevate the Caspase activity,and induce gastric cancer SGC-7901 cell apoptosis.The effects were be relevant to the time and dose of β-elemene. Conclusions β-elemene could induce SGC-7901 cells apoptosis by down-regulation of expression of Survivin and up-regulation of Caspase activity.
【CateGory Index】: R735.2
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 4 Hits
1 CHEN Xiao~(1), WEI Fu-xiang~(2), QU Yan-hui~(1)(1. College of Sciences, Hebei University of Science and Technology, Hebei Shijiazhuang 050018, China; 2. Department of Environment Science and Engineering, Hebei University of Science and Technology, Hebei Shijiazhuang 050018, China; 3. Department of Pharmaceutical, Hunan College of Traditional Chinese Medicine, Hunan Changsha 410007, China);Extraction of Essential Oil from Curcuma by SFE-CO_2[J];Huaxue Shijie (Chemical World);2005-10
2 XU Tao,XU Rui-an(Institute of Molecular Medicine,Huaqiao University,Quanzhou 362021,China);Progress on Ati-Tumor Mechanism of Chinese Medicine and Its Active Ingredients[J];Journal of Huaqiao University(Natural Science);2009-04
3 Chen Kai1 Zhu Hong2∥1.The First Affiliated Hospital of Suzhou University(Suzhou Jiangshou 215006,China) 2.Basic Medical and Biological College,Suzhou University(Suzhou Jiangshou 215006,China);Effect of Chinese Compound Medicine Combined with 5-FU on Survivin and Caspase-3 of HepG_2 Cells[J];Journal of Sichuan of Traditional Chinese Medicine;2009-02
4 JIANG Yu-guang, LIN Hong-sheng;Research Progress on the Impact of Traditional Chinese Medicine on Survivin Gene[J];Bulletin of Chinese Cancer;2006-06
Chinese Journal Full-text Database 2 Hits
1 FAN Yu,LIN Geng jin,QIAN Li ping,LI Hua △ ,ZHU Hang △△ ,YAN Ji li △△△ (Department of Gastroenterology, △△ Department of Loboratory,Huashan Hospital,Fudan University, Shanghai 200040, △Department of Pathology,School;Effect of Elemene on the Telomerase Activity and Apoptosis of Gastric Cancer SGC?7901 Cell Line[J];Journal of Shanghai Medica(University);2001-01
2 SUN Deng jun,FANG Qin △ , WANG Ji shi △△ (Department of Pharmacy,Guiyang Medical College, Guiyang 550000, △ Department of Pharmacy, Affiliated Hospital of Guiyang Medical College, Guiyang 550000, △△ Department;Elemene Induces Apoptosis and Regulates Expression of Bcl-2 Protein in Human Hepatic Cancer 7402 Cells and Cervix Cancer Hela Cells[J];Journal of Shanghai Medica(University);2001-05
Chinese Journal Full-text Database 10 Hits
1 Zhang Chen,Lv Shuqin,Zhang Yani,et al Changhai Hospital,Second Military Medical University,Shanghai (200433);Inhibition Effect of Chinese Traditional Medicine Injections on Human Hepatom Cell Lines in Vitro[J];Journal of Zhejiang College of Tcm;2005-06
2 Wang Huaijin,Zhao Jinbo,Yang Xiaoyan,et al The Second Affiliated Hospital of Dalian Medical University;The clinical study of treatment of cerebral metastatic cancers with Elemene[J];JOURNAL OF DALIAN MEDICAL UNIVERSITY;1999-02
3 REN, Yun-Fenga,b CHENG, Kang-Mina,b LIU, Gui-Fenga,b SUN, Yan-Honga SHEN, Yu-Mei,a (a Radiopharmaceutical Centre, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800) (b Graduate School of the Chinese Academy of Sciences, Beijing 100049);Synthesis, Radiosynthesis and Anticancer Activity of β-Elemene Tricarbonyl Rhenium Complex[J];Acta Chimica Sinica;2008-04
4 QI Xiao-jun WANG Feng;Effect of TACE with β-elemene and Lipiodol on Apoptosis and Proliferation of VX2 Carcinoma of Rabbits[J];Contemporary Medicine(Chinese Journal of Interventional Radiology);2008-04
5 QI Da guang(Beining City People Hospital,121300,Beining,China) YI Fu xin,QIU Jian wu, et al (Department of Neurosurgery,First Affiliated Hospital of Jinzhou Medical College, 121000,Jinzhou,China.);Study on Immunotherapy of elemene cooperated with anti-CD3-anti-glioma against tumor[J];Journal of Jinzhou Medical College;2001-02
6 CAO Yang,CHEN Wen-na,ZHAO Dan-yu,MA Xian-de(Liaoning Univeristy of TCM,Shenyang 110032,Liaoning,China);An Experimental Study on the Motirational Effect of Elemene on Apoptosis of the Cell A549 of Pulmonary Cancer[J];Journal of Liaoning University of Traditional Chinese Medicine;2008-04
7 XU Tao,XU Rui-an(Institute of Molecular Medicine,Huaqiao University,Quanzhou 362021,China);Progress on Ati-Tumor Mechanism of Chinese Medicine and Its Active Ingredients[J];Journal of Huaqiao University(Natural Science);2009-04
8 NIE Ke,LI Xin(Shandong University of TCM,Jinan 250355,China);Mechanism studies of inhibiting proliferation effect of Chinese medicine on gastric cancer BGC cell[J];Journal of Shandong University of Traditional Chinese Medicine;2007-04
9 Yu Jiechang, Lu Weiyan, Xu Jingjuan, et al. (Department of Medicine , Jiangnan College, Wuxi, 214063);Inhibitory Effect of Elemene on the Proliferation of Human Tumor Cells in vitro[J];Shanghai J.of Immunology;1997-06
10 FAN Yu,LIN Geng jin,QIAN Li ping,XU Zu de △ ,LI Hua △ (Department of Gastroenterology,Huashan Hospital,Fudan University,Shanghai 200040, △Department of Pathology,School of Basic Medical Sciences,Fudan University,Shanghai 200032);Effects of β-elemene on the Telomerase Activity and Expression of Proliferating Cell Nuclear Antigen and DNA Content in Gastric Cancer and Precancerous Conditions in Rats[J];Journal of Shanghai Medica(University);2001-05
Chinese Journal Full-text Database 10 Hits
1 WANG Xiao-lan et al(College of Animal S&T,Shihezi University of Xinjiang,Shihezi,Xinjiang 832000);Identification of Staphylococcus in Milk[J];Journal of Anhui Agricultural Sciences;2006-10
2 QI Yong-hua et al(College of Animal Science,Henan Institute of Science and Technology,Xinxiang,Henan 453003);Isolation,Identification & Drug Sensitivity Test of the Pathogenic Bacteria of Cow Mastitis[J];Journal of Anhui Agricultural Sciences;2006-14
3 CAI Sheng rong,FANG Zhi bin,HUANG Kai quan,WANG Yuan xun (Department of Integrated Traditional and Western Medicine, Anhui College of Traditional Chinese Medicine, Anhui Heifei 230038, China);Research on Relativity between Hemorrheology Indexes and the Levels of Endothelin and Thromboxane B_2 in Rats with Lung Qi Deficiency Syndrome[J];Journal of Anhui Traditional Chinese Medical College;2003-05
4 WANG Tao1*, JIN Ge2, WANG Shu mei1, et al 1 Department of Respiratory Medicine, the First Affiliated Hospital, Henan Medical University, Zhengzhou 450052, P R China 2 The School of Basic Medical Sciences, Henan Medical University, Zhengzhou 450052,;Induced differentiation of human lung adenocarcinoma cells by cinnamic acid[J];CHINESE JOURNAL OF CANCER;2000-08
5 ZHAO Ai-guang 1* ,YANG Jin-kun 1 ,ZHAO Hai-lei 1 ,LIU Li-kun 2 1.Department of Oncology,Longhua Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 200032,P.R.China2.Shangxi Chinese Medicine Institu te,Taiyuan 030;Apoptosis Induction by Sijunzi Deco ction in Human Gastric Cancer Xenografts in Nude Mice[J];Chinese Journal of Cancer;2001-02
6 JIANG Ying li, SONG Jin dan* Key Laboratory of Cell Biology, Ministry of Public Health, China Medical University, Shenyang 110001, P.R.China;Apoptotic Induction of Xinjiang Shikonin on Human Colorectal Cancer CCL229 Cell[J];Chinese Journal of Cancer;2001-12
7 Zhou Hong -Yu 1 ,Shen Jian-Kang 1 ,Hou Ju-Sheng 2 ,Qiu Yong -Ming 3 ,Luo Qi-Zhong 3;Experimental Study on Apoptosis Ind uced by Elemene in Glioma Cells[J];Chinese Journal of Cancer;2003-09
8 Lan Hong, Lu You-Yong Beijing Laboratory of Molecular Oncology,Beijing Institute for Cancer Research,School of Oncology, Peking University, Beijing,100034, P.R.China;Effect of Allitridi on Cyclin D1 and p27~(Kip1) Protein Expression in Gastric Carc inoma BGC823 Cells[J];Chinese Journal of Cancer;2003-12
9 Yuan Shu-Lan, Wang Xiu-Jie, Wei Yu-Quan Key Laboratory of Biotherapy of Human Diseases,Ministry of Education,West China Hospital, Sichuan University, Chengdu,Sichuan,610041, P.R.China;Anticancer Effect of Tanshinone and Its Mechanisms[J];Chinese Journal of Cancer;2003-12
10 ZENG Xiao Li1, TU Zhi Guang2 1.Clinical Laboratory of Anzhen Hospital,Capital University of Medical Sciences, Beijing,100029, P.R.China 2.Department of Clinical Biochemistry,Chongqing University of Medical Sciences, Chongqing,400016, P.R.China;Induction of Differentiation by Ginsenoside Rh_2 in Hepatocarcinoma Cell SMMC-7721[J];Chinese Journal of Cancer;2004-08
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 WANG Luo-lin~(1*),NING De-shan~2,CHEN Lu-lin~2,DENG Hong-zhu~3(1.Guangdong Institute of Traditional Chinese Medicine,Guangzhou 510095,China;2.Guangzhou Hanfang Modern Chinese Medicine Research & Development Co.,Ltd.,Guangzhou 510240,China;3.Department of TCM,Southern Medical University,Guangzhou 510515,China);Study on Preparation of Yifuning Soft Capsule[J];Chinese Journal of Experimental Traditional Medical Formulae;2007-04
China Proceedings of conference Full-text Database 2 Hits
1 WANG Chao-jin YUAN Jin-feng LI yan-lei (College of Food Science and Technology,Shanghai Ocean University,Shanghai 200090,China);Study on acetylcholinesterase biosensor based on sol-gel material[A];[C];2008
2 YUAN Jin-feng WANG Chao-jin~* (College of Food Science and Technology,Shanghai Fisheries University,200090);Modification of superficial material on acetylcholinesterase biosensor[A];[C];2007
【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
1 Xu Xuejun, Zhou Zicheng, Luo Yuanhui, Lu Rong, Men Rongfu, Fang Dianchun (Department of Gasenterology, Southwest Hospital, Third Military Medical University, Chongqing, 400038);Elemene induced apoptosis of SMMC 7721 cells of human hepatocellular carcinoma[J];ACTA ACADEMIAE MEDICINE MILITARIS TERTIAE;1999-04
2 WANG Huimin *, SHI Jian, LIU Junhua, et al. *Affiliated Hospital of Nantong Medical College, Nantong 226001;Detection of telomerase activity using telomere repeat amplification protocol microtiter plate hybridization[J];Chinese Journal of Laboratory Medicine;1999-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved