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《ACTA ATADEMIAE MEDICINAE SHANGHAI》 1996-01
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TIME COURSE OF THE EFFECT OF ELECTROACUPUNCTURE ON IL 1 AND β-ENDORPHIN OF SURGICAL TRAUMA RATS

Du Lina; Jiang Jianwei; Wu Gencheng;Cao Xiaoding(State Key Laboratory of Medical Neurobiology, Department of Neurobiologr,School of Basic Medical Sciences,Shanghai Medical University, Shanghai 200032)  
PURPOSE To study the effect of electroacupuncture(EA) on immuneneuroendocrinal function after surgical trauma in rats.METHODS The 3H-TdR incubated assay was applied to measure the LPS-induced releasing of IL-1 from peritoneal macrophage. Using the radiooimmunoassay to determine the level of plasma corticosterone(Cs) and β─Endorphin (End).RESULTS The results showed that the IL─1 release from peritoneal macrophage was increasing at 2, 4, 8, 12 hours after surgical trauma (P0.05, P0.001). At 1, 2, 4, 8, 12 hours,the plasma β─End and Cs were increased as compared with control group (P0.05,P0.001).Using EA of Zusan li and Lanwei points(2Hz) for 30 min, it was found that the IL─1 level was only increased at 1, 2, 4 hours after surgical travma, but at 8 hours the IL─1 level was recovered to normal. Compared with the data from the same time (1,2,4,8,12 hours) in the trauma group, the increment of concentration of β─End and Cs is lower in EA group.CONCLUSIONS The results suggest that EA could exert regulatory effect towards normal during stress caused by surgical trauma.
【Fund】: 攀登计划项目资助
【CateGory Index】: R245-0
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