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《Laboratory Medicine》 2019-12
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Epidemiological characteristics of 7 common viruses among 0-12-year-old upper respiratory tract infection children in Songjiang district of Shanghai

GONG Ruhan;LIU Qingzhong;CHEN Shu;LIN Lihui;LUO Jialing;CUI Zelin;Department of Clinical Laboratory,Shanghai General Hospital,Shanghai Jiaotong University;  
Objective To investigate the epidemiological characteristics of common upper respiratory tract infectious viruses among children in Songjiang district of Shanghai,and to provide a reference for clinical treatment. Methods The nasopharyngeal secretion samples of 2 242 children with upper respiratory tract infection in Shanghai Jiaotong University Shanghai General Hospital(South Campus) from 2016 to 2018 were collected. Direct immuno?uorescence assay(DFA) was used to determine in?uenza virus type A(IVA) and in?uenza virus type B(IVB),adenovirus(ADV),parainfluenza virus(PIV) 1,PIV2,PIV3 and respiratory syncytial virus(RSV). Results Among the 2 242 children with upper respiratory tract infection,427 cases were positive for 7 kinds of respiratory tract infectious viruses,and the positive rate was 19.05%. The positive rates of 28 d,29 d-2 years and 3-5 years(top 3) were 28.57%,25.66% and 24.56%,respectively. The positive rate of RSV was the highest in inpatient children(16.26%) and outpatient children(10.19%). RSV mostly occurred in autumn and winter,PIV3 mostly occurred in spring,summer and autumn,and ADV occurred all year round. IVA and IVB were more common in spring and winter. Conclusions RSV is the most common virus in 0-12-year-old children with upper respiratory tract infection in Songjiang district of Shanghai,and most viral upper respiratory tract infections have a characteristic of seasonal epidemic. Clinic should do prevention and control according to the epidemiological characteristics of viruses.
【Fund】: 上海申康医院发展中心资助项目(16CR3098B);; 上海市青年临床医技人才(临床检验专业)培养资助计划(沪医卫基〔2016〕04号)
【CateGory Index】: R725.6;R446.6
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