Full-Text Search：
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《ACTA UNIVERSITATIS TRADITIONIS MEDICALIS SINENSIS PHARMACOLOGIAEQUE SHANGHAI》 1999-04
Add to Favorite Get Latest Update

Comparative Study on aging-retarding Effects of Herbal Formulas and Drugs to Tonify the Kidney, to Strengthen the Spleen, to Benefit Qi and to Harmonize Blood

ZHAO Wei-kang; LIN Shui-miao;CHEN Sha-wei; XU Ping-chu;JIN Guo-qin;ZHAO De-min;WEI Hong-chang(Institute of Geriatric Medicine, Shanghai University of Traditional Chinese Medicine)  
In exploration of the similar and different points in the aging-retarding effects of various types of the formulas and drugs to tonify the kidney strengthen the spleen, benefit qi and harmonize blood, the indexes related to senility were selected from neuroendocrine, immune function, anti -free radical, platelet aggregation and hepatic protein and pulmonary cAMP content, to test, compare and study simultaneously the aging-retarding effects of the above-mentioned formulas and drugs in naturally-aging rats, The results showed that the above-mentioned formulas and drugs can all enhance the spleen IL-2 activity, hepatic protein content, cerebral and hepatic SOD content and decrease hepatic LPO, serum E2 and platelet aggregation in the naturally-aging rats. But, the effect was most extensive and obvious in retarding aging of pituitary-gonad function in the old rats in the kidney-tonifying group, in rearding aging of the cerebral function in the qi benefiting group and was obvious in enhancing the pulmonary cAMP content in the old rat in the blood -harmonizing group. Various groups of the formulas and herbal drugs can all enhance the hepatic protein content, but the functional mechanisms are different.
【Key Words】： The Kidney-tonifying spleen-strengthening qi-benefiting and blood harmonizing herbal formulas and drugs naturally-aging rat retard aging
【Fund】： 国家中医药管理局基金!922185
【CateGory Index】： R285
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 4 Hits
1 LI Zhi-ping1 ZHAO Wei-kang2 XU Pin-chu2 CHEN Fang-min2 YAO Ming-zhong2 1. Biochemistry Teaching and Research Section of Shanghai University of TCM 2. Institute of Geriatrics, Shanghai University of TCM;Effects of Kidney-Tonifying and Spleen-Fortifying Ricipes on Expression of Senescence-Associated Genes in Liver of Aged Rats[J];Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai;2008-04
2 LI Hua1 YE Ting-jie1 LI Bo-qing2 YING Xin-ping21.Basic Medicine School,Shanghai University of Traditional Chinese Medicine2.Teaching Experiment Center,Shanghai University of Traditional Chinese Medicine;Effects of Cordyceps Polysaccharides on Fibroblasts Collagens in Photoaging Skin Induced by 8-MOP/UVA[J];Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai;2009-04
3 LIN Shui miao,ZHAO Wei kang,XU Pin chu,et al(8);Status and Action of the Theory of “Deficiency and Decline in Essence and Blood”in TCM Study on Senility Postponement[J];SHANGHAI JOURNAL OF TRADITIONAL CHINESE MEDICINE;2000-04
4 CHEN Fang-min, ZHAO Wei-kang, XU Pin-chu, et al Institute of Geriatrics, Shanghai University of TCM, Shanghai (200032);Comparative Study on the Regulatory Effects on Senescence Related Cell Cycle Gene Expression by TCM Prin- ciples of Tonifying Shen, Invigorating Pi Benefiting Qi, and Activating Blood Circulation[J];Chinese Journal of Integrated Traditional and Western Medicine;2003-11
【Citations】
Chinese Journal Full-text Database 2 Hits
1 Mo Qizhong Fang Jim Gong Bin Wang JumciQian Xuping Kuang Xingwei Chen Rong(Shanghai Chinese Medical College)Wu Bohui (Shanghai Institute of Chemical Reagent);~(125)I-labelled-radioimmunoassay for the cyclic AMP[J];Nuclear Techniques;1986-09
2 Wang,Dao-yuan Zhou,De-he Cai,Guo-qiang (Shanghai Institute of Meterin Medico,Academia Sinica,Shanghai);PURIFICATION OF RIBONUCLEASE-INHIBITOR FROM HUMAN PLACENTA AND ASSAY IN ERYTHROCYTE[J];;1986-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 WANG Zhan-xiang, ZHANG Xiang, FEI Zhou, et al. (Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, P. R. China);Suppression effect of ribonuclease inhibitor on the growth of glioma cells[J];CHINESE JOURNAL OF CANCER;2000-01
2 Liao Han; Zhang Qiujun; Ma Jun; et al.(Shanghai University of Chinese Traditional Medicine, Shanghai 200032 );Effect of Bac-Chun-Fang on Cyclic Nucleotide Content in Tissues of Old Rats[J];LABELED IMMUNOASSAYS AND CLINICAL MEDICINE;1997-04
3 Jin Guoqin; Zhao Weikang; Xu Pingchu et al.(Department of Biochemistry, Shanghai University of Traditional Chinese Medicine, Shanghai 200032);Effect of Tonifying Kidney Chinese Medicine on Retarding Senile Change of Hypothalamus-Pituitary-Thyroid Axis Function in Old Rats[J];LABELED IMMUNOASSAYS AND CLINICAL MEDICINE;1998-01
4 Fang Jun; Guo Xin; Pan Yingyi et al.(Shanghai University of Traditional Chiners Medicine, Shanghai 200032);Effects of Ping Chuan Gu Ben Recipe on β-Adrenergic Receptor,Adenylate Cyclase and Cyclic Nucleotide in Pulmonary Tissue of Asthmatics Guinea Pig[J];LABELED IMMUNOASSAYS AND CLINICAL MEDICINE;1998-02
5 Ye Weixin (Toregji Medical University);The present situation and development on the research of radioimmunoassay methodology[J];Nuclear Techniques;1987-07
6 Cao Qian Wang Jigeng(Shuguang Hospital, Shanghai College of TCM, Shanghai 200021)Gong Bin Fang Jun(Shanghai College of Traditional Chinese Medicine,Shanghai 200032);The pharmacological effect of Epimedium Brevicornum Maxim and Radix Rehmannial Liquid studied with in vitro radioassay[J];Nuclear Techniques;1992-11
7 Yang Chunlong 1, Gong Guoji 2 and Tan Fujie 2 ( 1College of Basic Sciences, 2Dept of Plant Protection, Nanjing Agric Univ, Nanjing 210095);EFFECT OF DELTAMETHRIN ON CYCLIC NUCLEOTIDE LEVELS OF MYTHIMNA SEPARATA WALKER[J];JOURNAL OF NANJING AGRICULTURAL UNIVERSITY;1996-03
8 LUO Hui-lan1,CHEN Yong-sheng3,XIE Fang4,SUN Jin-jin2 1Cardiovascular Ward of Cadres,2Department of Cardiology,Air Force General Hospital,Beijing 100142,China 3Institute of Aviation Medicine,Beijing 100142,China 4Department of Nephrology,Second Hospital of Huangshi,Huangshi,Hubei 435002,China;Effect of repeated and prolonged +Gz exposure on endocrine function of vessel in a rabbit model of atherosclerosis[J];Medical Journal of Chinese People's Liberation Army;2012-09
9 Chen Kunhua; Fang Jun; Gong Bin;Mo Qizhong; Quan Hongpo;Sun Wanping(Shanghai University of Traditional Chinese Medicine, Shanghai 200032);The Enhancing Effect of Rabus of RubusChingii Hu the Lymphocyte Proliferation and its Relationship with Cyclic Nucleotides[J];SHANGHAI J.OF IMMUNOLOGY;1995-05
10 Zhao Weikang;Dai Xiangdong;Shento Shujun Institute of Geriatrics Shanghai University of Traditional Chinese Medicine(200032);Study on the Function of Heart-Benefitting Recipe to Animal Model of“Dementia”and Dysmnesia[J];Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai;1998-02
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 GUO Li-rong~1,LIANG Shuang~1,LI Feng~1,GUO Zhong-yu~1,LI Fang-fei~△,ZHU Shi-gong~2,LI Yang~(1*)(1.Department of Pathophysiology,School of Basic Medical Sciences,Jilin University,Changchun 130021,China;2.Department of Physiology,Medical Section of Beijing University,Beijing 100081,China);Effect of anti-aging oral preparation on free radical in senescent rats[J];Journal of Jilin University(Medicine Edition);2006-04
2 WU Zhao-xia1, WANG Xiao-hua1, LIU Hua1, DENG Hong-zhu2 1Department of Biochemistry, Guangzhou Medical College, Guangzhou 510182, China; 2Department of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China;Effects of the mixture of Rhizoma Curcumae and Oviducts Ranae on estrogen and its receptor expressions in ovariectomized rats[J];Journal of Southern Medical University;2008-05
3 LIANG Lei1, ZHANG Xu-hui2, ZHOU Yi3, HUANG Yu-juan1, DENG Hong-zhu1 1College of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China; 2Department of Oncology, Second People's Hospital of Guangdong Province, Guangzhou 510317, China; 3Department of Pharmacy, Guangzhou College of Medicine, Guangzhou 510182, China;Protective effect of Oviductss Ranae capsules on the reproductive organs of aged mice[J];Journal of Southern Medical University;2008-06
4 LIU Ying,CAO Jun-hao(Department of Laboratory,Wuhan General Hospital of Guangzhou Command,Wuhan,Hubei,430070,China);Progress on Aging Animal Model[J];Progress in Veterinary Medicine;2007-12
5 Li Zhigang,Lan Rongfang,Guanli,Liu Zhengxiang (Department of Cardiology , Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China);EFFECT OF GINSENOSIDE Rg_1 ON ENDOTHELIAL APOPTOSIS INDUCED BY OxLDL AND MOLECVLAR MECHANISM[J];Chinese Journal of Histochemistry and Cytochemistry;2002-03
6 ZENG Chang-chun1,LI Cheng-zhe2,MEI Wu-xuan2(1 College of photoelectricity in southern Normal University,Guangzhou Guangdong 510631; 2 The First Affiliated hospital of Guangzhou University of TCM,Guangzhou 510405);THE STUDY OF THE RELATION BETWEEN PHLEGM AND SENILITY[J];Gansu Journal of Traditional Chinese Medicine;2004-04
7 MENG Jihong,RAO Qing State Key Laboratory of Experimental Hematology,Institute of Hematology & Blood Diseases Hospital,Chinese Academy of Medical Science & Peking Union Medical College,Tianjin,300020,China;The Signaling Pathways Triggering Cellular Senescence[J];Journal of Medical Molecular Biology;2006-06
8 ZOU Xiang-yang~1,LI Lian-hong~2.(~1Department of Biology,Dalian Medical University,Dalian 116027;~2Department of Pathology,Dalian Medical University,Dalian 116027,P.R.China)Correspording anthor: ZOU Xiang-yang.E-mail: zouxiangyang@126.com;Cell Cycle Control and Tumor[J];International Journal of Genetics;2006-01
9 Chen Lin,Jiang Bo,Zhang Yali,et al.(Institute for Digestive Diseases,Nan Fang Hospital, Nan Fang Medical University, Guangzhou 510515 China);STUDY THE EXPRESSION OF CLAUDIN-1 IN HUMAN COLORECTAL CARCINOMA CELL LINES BY FQ RT-PCR AND WESTERN BLOT[J];Journal of Guangxi Medical University;2007-02
10 LIU Yu,LIU Lian-xin(Xuzhou College for Industrial Technology,Xuzhou 221140,China);Ingredient and pharmacology research progress of Oviductus Ranae[J];Strait Pharmaceutical Journal;2007-12
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 YAO Hui1, WANG Xiao-juan1, HUANG Li-ping2, DIAO Jian-xin3, DENG Hong-zhu1 1College of Traditional Chinese Medicine, 2Department of Gynecology and Obstetrics, Nanfang Hospital, 3Laboratory of Molecular Biology, College of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China;Effect of Oviductus Ranae on Cyclin D1, CDK6 and P15 expressions in the liver tissue of aged male rats[J];Journal of Southern Medical University;2010-05
2 LIU Yaling 1,FANG Xiang 1,SHI Li 1,YAN Qingwen 1,FENG Wenting 1,ZHANG Yonghua 1,ZHAO Chunyang 1,LU Shenglou 1,LIU Hong 1,2(1.College of Chemistry and Chemical Engineering,Hainan Normal University,Haikou 571158,China;2.Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education,Haikou 571158,China);Protective Effec of Topical Use of Miquel Oxyphylla Cream on Photoaging Skin in Mice[J];Journal of Hainan Normal University(Natural Science);2011-04
3 MA Zhuo-fei1,ZHENG Ying2,LIN Yan-ming1(1.Youjiang Medicine College for Nationalities,Baise 533000,Guangxi,China;2.Ruikang Hospital Affiliated to Guangxi University of Traditional Chinese Medicine,Nanning 530001,Guangxi,China);Review of Recent Study on Chinese Herb's Mechanism of Resisting Skin Photoage[J];Journal of Liaoning University of Traditional Chinese Medicine;2012-01
4 ZHANG Bin1,ZHANG Lu1,LI Shasha1,JIANG Xiao1,ZHU Hongxia1,HUANG Zhigang2(1.School of Traditional Chinese Medicine,Southern Medical University,Guangzhou 510515,Guangdong,China;2.Jiuhui Pharmaceutical Co Ltd.,Huizhou 516007,Guangdong,China);Connection of Plant Polysaccharide with Cosmetics[J];Journal of Liaoning University of Traditional Chinese Medicine;2013-01
5 ZHANG Chen;ZHANG Jin;HUANG Jin;ZHAN Fei;LI Jiebin;Basic Medical College of Guangzhou University of Chinese Medicine;Guangzhou University of Chinese Medicine Clinics;;Analysis Based on Stem Cells Kidney Essence Theory and Mechanism of Aging[J];Liaoning Journal of Traditional Chinese Medicine;2014-09
6 LU Jin bao,ZHOU Ru qian, LIU Ren ren,XUE Ren hua Directed by LIN Shui miao,ZHAO Wei kang Institute of Geriatrics,Shanghai University of Traditional Chinese Medicine;Investigation and Analysis of Kidney Deficiency and Patterns in the Elderly[J];Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai;2002-01
7 LI Zhi-ping1 ZHAO Wei-kang2 XU Pin-chu2 CHEN Fang-min2 YAO Ming-zhong2 1. Biochemistry Teaching and Research Section of Shanghai University of TCM 2. Institute of Geriatrics, Shanghai University of TCM;Effects of Kidney-Tonifying and Spleen-Fortifying Ricipes on Expression of Senescence-Associated Genes in Liver of Aged Rats[J];Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai;2008-04
8 CHEN Chuan CHI Hui-ying YU Zhi-hua CHEN Jiu-lin Shanghai Geriatric Institute of Traditional Chinese Medicine;Effect of "Shoushen Granule" on Vascular Pathology and Oxidative Stress in Rats with Atherosclerosis[J];Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai;2012-03
9 Shi Yunfeng,Hu Bing,An Hongmei(Hualong Hospital Attached to Shanghai University of Traditional Chinese Medicine,Shanghai,200032);Study of Cell Aging and Traditional Chinese Medicine and Pharmacology[J];Journal of Shaanxi College of Traditional Chinese Medicine;2007-02
10 ZHOU Yan-yan;GUO Yu-hui;ZHOU An-fang;XU An-li;ZHAO Min;Hubei University of Chinese Medicine;China Three Gorges University;;The Influence of the deficiency of kidney and spleen-Yang on the brain hippocampus cells cycles and on FOXO3a protein expression of model mice[J];Lishizhen Medicine and Materia Medica Research;2014-02
China Proceedings of conference Full-text Database 1 Hits
1 Zhangchen,Huangjin,Zhangjin,Zhanfei (School of Basic Medical Sciences,Guangzhou University of Traditional Chinese Medicine,Guangzhou 510405,China);Based on stem cells "kidney essence" theory and mechanism of aging[A];[C];2013
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved