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《世界针灸杂志(英文版)》 2010-03
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Study on efficacy and safety of acupuncture for treatment of functional constipation

ZHANG Chao-xian QIN Yong-mei Department of Gastroenterology,The First Affiliated Hospital of Xinxiang Medical College,Weihui 453100,Henan Province,China WANG You-jing  
Objective To explore clinical efficacy and safety of acupuncture in treatment of functional constipation.Methods One hundred and twenty cases were randomly divided into an observation group and a control group,60 cases in each group.The patients in the observation group were treated with acupuncture at Tiānshū(天枢 ST 25),Shàngjùxū(上巨虚 ST 37),Zúsānlǐ(足三里 ST 36),Dàchángshū(大肠俞 BL 25),etc.,and the control group was treated with oral administration of Macrogol 4000 and Mosapride.Defecation frequency,stool property,constipation symptom score,accompanying symptom score,gastrointestinal transit time and adverse reaction were observed before treatment,at the end of treatment and 4 weeks after treatment in the two groups.Results Compared with those before treatment,defecation frequency was increased significantly at the end of treatment in the two groups,while stool property,constipation symptom score,accompanying syndrome score and gastrointestinal transit time all were decreased significantly(all P0.01),with no significant difference in these indexes between the two groups at the end of treatment (all P0.05).Compared with the end of treatment,the above-mentioned indexes did not significantly recur in the observation group 4 weeks after the treatment (all P0.05),but the therapeutic effects were unstable with decreased to some extent in the control group (all P0.05).No serious adverse reaction was found in the two groups.Conclusion In the patients with functional constipation,acupuncture can significantly increase defecation frequency,change stool property,alleviate constipation and accompanying symptoms,and shorten gastrointestinal transit time with better safety and tolerance,and the therapeutic effect is more stable than that of Macrogol 4000 and Mosapride.
【CateGory Index】: R246
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