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《CHINESE JOURNAL OF NEUROANATOMY》 1997-03
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EFFECTS OF MOTONEURONOTROPHIC FACTOR ON ACUTE EXPERIMENTAL SPINAL CORD TRAUMA DUE TO IMPACT IN RATS

Zhou Changman; Xu Shaoding;Wang Xueming; Chen Biao(Departrnent of Anatomy, Beijing MedicaI College of PLA, Beijing)  
The effects of motoneuronotrophic factor(MNTF, 35 kD) on the spinal cord trauma was studied on 32 adult Wis-tar rats divided into 4 groups. The experimental model of cornplete (545 gcf) and incompleted (2l8 gcf) spinal cord trauma was made by means of Allen's method, and the MNTF experiment and control (salt solution) were rnade respectively. Four weeks after operation, Glees, Nissl staining and ChAT, GFAP immunohistochemical staining were used. The result sug-gested that the MNTF might promote the nerve regeneration in incornpleted spinal cord trauma,but un fortunately, there is no distinct effect on the complete trauma of spinal cord.
【CateGory Index】: R363
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