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《CHINESE JOURNAL OF NEUROANATOMY》 1998-02
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RESPONSES OF HABENULAR NEURONS TO BOTH BARORECEPTIVE AND NOXIOUS STIMULATIONS

Zhao Hua; Hua Shucheng; Fang Jiazhi; Wang Shao (Department of Physiology, Norman Bethune University of Medical Sciences, Changchun)  
Recently, we reported that excitatory stimulation of habenular nucleus (Hb) resulted in a parallel changes in both blood pressure and pain threshold. The present study was designed to observe the effects of baroreceptive and noxious stimulation on neuronal discharges of Hb recorded extracellullary by glass microelectrodes in anesthetized rats. The baroreceptor was stimulated by intravenous injection of phenylaphrine (1~2 mg/kg b. w. ). The results showed that 75% pain-excitatory units were excited, whereas 63% pain-inhibitory units were inhibited by baroreceptive stimulation, suggesting that most of the Hb neurons receive information from both peripheral nociceptive and baroreceptive afferents. After intracerebroventricular administration of morphine, the spontaneous and evoked discharges of Hb neurons in response to both noxious and baroreceptive stimulation were obviously changed. The responsiveness of baroreceptor-excited units were enhanced, whereas that of baroreceptor-inhibited units were reduced respectively in parallel with the decrease in blood pressure. The present results indicated that morphine may strengthen the activities of Hb neurons in response to changes in blood pressure, and the correlative changes in pain threshold and blood pressure may be involved in the processing of defence cardiovascular reaction.
【CateGory Index】: R363
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【References】
Chinese Journal Full-text Database 1 Hits
1 ;可卡因对大鼠痛阈和缰核痛相关神经元放电的影响[J];Chinese Journal of Applied Physiology;2006-02
【Citations】
Chinese Journal Full-text Database 5 Hits
1 Wang Shao Xia Yinghong(Department of Physiology, Bethune Uuniversity of Medical Sciences) The vassopressor effect induced by exciting habenula is observed. In order to judge whether habenula participates the process of blood pressure regulation and to distinguish this function from the pain response in habenula or not, the experiment is carried out.Rising arterial blood pressure by norepinephrine (0.06 mg i. v. ) can increase the unit spontaneous firing rat from habenula in rats.And the unit spontaneous firihg rate is lowered by decreased arterial blood pressure with sodium nitroprus side (0.018 mg i. v. ) . After administration of morphine or fentanyl, the response of increasing spontaneous firing rate from habenula to pain stimulus disappears, but the increased firing rate induced by the increased blood pressure exists as before. It is suggested that habenula is involved in the activities of cardiovascular regulation. Hsbcnula Spontaneous firing rate vassopressor effect;Effects of Arterial Blood Pressure on Firings from Habenula[J];;1989-03
2 LIU WEI-MIN;WANG SHAO Department of Physiology, Norman Bethune University of Medical Sciences, Chang Chun;EFFECT OF STIMULATION OF BASOLATERAL AMYGDALOID NUCLEUS ON UNIT DISCHARGES OF NEURONS OF HABENULAR NUCLEUS[J];Acta Physiological Sinica;1987-04
3 LI ZHONG-SI;LIU XI-YI Department of Physiology,Zhanjiang Medical College,Zhanjiang 524023;DEPRESSOR EFFECT OF NUCLEUS ARCUATUS STIMULATION IN CHRONIC STRESS-INDUCED HYPERTENSIVE RAT[J];Acta Physiological Sinica;1992-02
4 ZHAO HUA AND WANG SHAO (Department of Physiology, Norman Bethame University of Medical Sciences, Changchun 130021);DIFFERENT EFFECT OF L-GLUTAMATE MICROINJECTION INTO MEDIAL OR LATERAL HABENULAR NUCLXU ON PAIN THRESHOLD[J];ACTA PHYSIOLOGICA SINICA;1995-03
5 Zhao Hua,Yang Wei,Wang Shao,Jin Yuxiang (Department of Physiology, Department of Anatomy,Norman Bethune University of Medical Scienees,Changchun 130021);RELATIONSHIP BETWEEN BLOOD PRESSURE AND PAIN THRESHOLD CHANGES ENDUCED BY EXCITING RESPECTIVELY MEDIAL AND LATERAL HABENULAR NUCLEUS[J];CHINESE JOURNAL OF APPLIED PHYSIOLOGY;1995-04
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 PU QINGGONG FU JIYI WANG SHAO LI LUOYIKG (Department of Physiology, Bethune Medical College, Changchun);EFFECT OF PREOPTIC AREA AND AREA HYPOTHALAMUS LATERALIS ON "PAIN" UNIT DISCHARGE IN LATERAL HABENULAR NUCLEI[J];Acta Zoologica Sinica;1982-04
2 Fang Jiazhi, Wang Shao;Influence of nucleus habenula on discharging from painrelating neurons in periaqueductal gray matter[J];;1984-06
3 Wang Shao;The effect of nucleus accumbens stimulation on discharging in the periaquaeductal grey matter in acupuncture analgesia[J];;1985-01
4 Kao Changqing Wang Shao;Effects on discharging from lateral habenular nucleus by naloxone microinjection into nucleus accumbens[J];;1985-01
5 Liu Minzhi et al;Effect Of hippocampus stimulation on spontaneous discharges of pain-sensitive neurons of habenular nucleus[J];;1985-02
6 Wang Shao;Role of the descending pathway from the forebrain through the habenula in acupuncture analgesia[J];;1987-01
7 Tang Zhigang and Wang Shao;Excitation of the habenular nucleus with acetylcholine and its effect on the pain threshold in rats[J];;1987-05
8 PAN Yu zhen 1,XIA Ying hong 1,YAN Li 1,WANG Shao 1,WU Shui sheng 2 (1 Dept.of Physiology,School of Basic Medical Sciences,Jilin University,Changchun 130021 China; 2 Dept.of Medicine,First Hospital,Jilin University) 〔;Effect of losartan on arterial blood pressure and unit dischargings of habenular neurons in rat[J];Journal of Norman Bethune University of Medical Science;2001-01
9 JIN Yu xiang 1, CHEN Jia feng 2, HU Bo 1, ZHANG Li young 1 HAN Li chun 3, WANG Shao 2 (1.Institute of Cytology and Genetics, Northeast Normal University, Changchun 130024, China; 2.Department of Physiology, Norman Bethune University of Medica;Effect of insulin and glucagon on unit discharge of neurons in rat medial habenular nucleus[J];JOURNAL OF NORTHEAST NORMAL UNIVERSITY (NATURAL SCIENCE EDITION);2000-03
10 Li Suje,et al ( Department of physiology );Effect of visceral and somatic stimuli on unit-discharges of pain-related neurons in lateral habenular nucleus[J];Journal of First Military Medical University;1985-03
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Guo Hui, Chi Huanfang, Wang Shoubiao, et al Department of Anatomy, Qingdao Medical College, Qingdao 266021;OBSERVATION OF NERVE FIBER CONNECTIONS BETWEEN LOCUS COERULEUS AND DORSAL COLUMN NUCLEI IN RATS[J];;1997-01
2 ZUO Ming Xue (Department of Biology, Beijing Normal University, Beijing 100875, China);EFFERENT PROJECTIONS OF THALAMICAL AUDITORY NUCLEI IN RING DOVE[J];ACTA ZOOLOGICA SINICA;1998-01
3 Gao Tian-li, Bao Xiao-feng, Ma Yu-ling (Department of Biology,Peijing University; Laboratory of Cardiovascular Disease,Xi Yuan Hospital, Academy of TraditionalChinese Medicine);Studies on the Role and the Conduction Pathway of Electric Acupuncture at Points “nei guan” and “shen men” in the Treatment of Experimental Arrhythmia[J];Acta Scicentiarum Naturalum Universitis Pekinesis;1980-04
4 He Hongbin, Zhao Fuqiang, Wang Qilin (Biomedical Engineering Department of Capital University of Medical Scieces ,100054);Adaptive Noise Cancelling Algorithm Used for Detectionof Evoked Potentials[J];BEIJING BIOMEDICAL ENGINEERING;1997-03
5 ;THE EFFECT OF STIMNLATING AND DESTROYING HABENULA ON THE ANIMAL PAIN THRESHOLD[J];;1980-04
6 XU Hai-yan, YU Lei, LI Hua-li , ZHAO Hua , LIU Yong-feng, ZHANG Cheng-wei ( Department of Physiology, School of Basic Medical Sciences, Jilin University, Changchun 130021, China; Department of AnestheSiology, Second Hospital, Jilin University, Changchun 130041, China);Electrophysiology of functional relationship between dorsal raphe and habenular nucleus[J];Journal of Jilin University(Medicine Edition);2006-01
7 Pan Yuzhne;Huang Min;Wu Jianqun et al(Department of physiology);Elcectro-acupuncture analgesia produced by septal area inhibiting habenula activity with GABAA[J];JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE;1996-05
8 Wang Li Lin Haoran Zhang Weimin (Department of Biology, Zhongshan University, Guangzhoiu 510275);EFFECTS OF DIFFERENT HYPOTHALAMIC PEPTIDES AND NEUROTRANSMITTERS ON GONADOTROPIN AND GROWTH HORMONE SECRETION IN COMMON CARP ( Cyprinus carpio L.)[J];ZOOLOGICAL RESEARCH;1997-01
9 WANG Guang-ying, WANG Shou-kun (College of Animal Science, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China);Controlling of reproductive hormones on poultry broodiness[J];;2005-01
10 LIU Wu-yi,FANG Di-an (1.Department of Scientific Research, Fuyang Teachers College , Fuyang, Anhui, 236032,China); (2.Animal Science and Technology school of Anhui Agriculture University, Hefei, Anhui, 230036,China);Review of the Study on Fowl Prolactin[J];Journal of Fuyang Teachers College Natural Sciences;2005-01
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 ZHANG Chun-xiao,ZHANG Wen-jie,LIU Yong-feng,WANG Shao1(Department of Physiology,School of Basic Medical Sciences,Jilin University,Changchun 13021,China);EFFECTS AND POSSIBLE MECHANISM OF COCAINE ON THE NEURONS OF LATERAL HABENULAR NUCLEUS[J];Chinese Journal of Applied Physiology;2007-04
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 PU QINGGONG FU JIYI WANG SHAO LI LUOYIKG (Department of Physiology, Bethune Medical College, Changchun);EFFECT OF PREOPTIC AREA AND AREA HYPOTHALAMUS LATERALIS ON "PAIN" UNIT DISCHARGE IN LATERAL HABENULAR NUCLEI[J];Acta Zoologica Sinica;1982-04
2 ;THE EFFECT OF STIMNLATING AND DESTROYING HABENULA ON THE ANIMAL PAIN THRESHOLD[J];;1980-04
3 Liu Minzhi et al;Effect Of hippocampus stimulation on spontaneous discharges of pain-sensitive neurons of habenular nucleus[J];;1985-02
4 FU JIYI;FU QINGGONG AND WANG SHAO(Department of Physiology,Bethune Medical College);EFFECT OF STIMULATION OF SEPTAL REGION ON PAIN-RELATED NEURONS OF LATERAL HABENULAR NUCLEUS OF RATS[J];Acta Physiological Sinica;1982-04
5 SUN XIANG-YING;YAO TAI(Department of Physiology,Shanghai First Medical College,Shanghai);INHIBITORY EFFECT OF ELECTRIC NEEDLING ON THE DEFENCE REACTION PRODUCED BY HYPOTHALAMIC STIMULATION IN AWAKE RABBITS[J];Acta Physiological Sinica;1985-01
6 KAO CHANG-QING;WANG SHAO(Department of Physiology,Bethune Medical College,Changchun);EFFECT OF STIMULATION OF NUCLEUS ACCUMBENS AND NALOXONE MICROINJECTION ON NOCEPTIVE UNIT DISCHARGES IN THE LATERAL HABENULAR NUCLEUS[J];Acta Physiological Sinica;1985-01
7 SUN XIANG-YING;YAO TAI Department of Physiology, Shanghai Medical University;PERIAQUEDUCTAL GREY MATTER PARTICIPATES IN THE INHIBITORY EFFECT OF ELECTRICAL NEEDLING ON DEFENCE REACTION[J];Acta Physiological Sinica;1986-05
8 LI HUI-LIN;WANG QING;WANG QI;GU YUN-HUI Department of Physiology, Beijing Medical University,Beijing;FUNCTIONAL RELATIONSHIP BETWEEN PRESSOR EFFECT OF SUBSTANTIA NIGRA AND DEPRESSOR EFFECT OF NUCLEUS ARCUATUS HYPOTHALAMI[J];Acta Physiological Sinica;1988-01
9 YANG SHAO-NIAN;WANG SHAO Department of Physiology,Norman Bethune University of Medical Science, Chang Chun;THE ROLE OF THE VENTRAL MEDULLA OBLONGATA IN THE VASOPRESSOR REACTION INDUCED BY HABENULAR NUCLEUS STIMULATION[J];Acta Physiological Sinica;1988-03
10 Zhai xiaozhung Chen gongbai Mo wang-ing Jiang cheng-chuan Li shengchang Xu meifen (Research Laboratory of Clinical Neurophysiology,Institute of Neurology,Shanghai First Medical College);ROLE OF AMYGDALA IN ACUPUNCTURE ANALGESIA——EXPERIMENT REPORT IN ANIMALS[J];Acupuncture Research;1981-03
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