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《Chinese Journal of Neuroanatomy》 2002-01
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THE DISTRIBUTION OF BRAIN-DERIVED NEUROTROPHIC FACTOR IN BRAIN OF ADULT MONKEY

Li Liyan, Wang Tinghua *, Yang Zengwei ** , Cheng Yanhong *, Li Lang *** , Liu Zhongliang *** (Department of Histology and Embryology, *Reserch Institute of Neuroscience, *** Department of Anatomy, Kunming Medical College, Kun  
The distribution of brain derived neurotrophic factor(BDNF) in brain of adult monkey was studied by immunohistochemical method using specific antiserum of BDNF. The results were as following: The positive reaction of BDNF LI was observed in neurons and dendrites of layers Ⅲ~Ⅴ in cerebral cortex, Purkinje cell, Basket cell and Golgi cell of cerebellum, neurons of hippocampus, nucleus lentiformis, nuclei caudati, nuclei paraventriculares, nuclei pontis, nucleus nervi hypoglossi, nucleus dorsalis nervi vagi, nucleus vestibularis, nucleus olivaris caudalis and formatio reticularis. In addition, a few positive glias of BDNF LI were also observed in white matter of cerebum and cerebellum. The results suggest that BDNF LI may exist widely in the monkey brain, and may be concerned with various types of neurons. These data is useful to explore the role of BDNF in adult brain of primates.
【CateGory Index】: R329
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